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Lecture 9
Lecture 9: Muscles
| Question | Answer |
|---|---|
| Epimysium | outermost layer of muscle composed of dense irregular connective tissue |
| Perimysium | layer of fibrous connective tissue that wraps the muscle fascicle |
| Muscle Fascicle | groups of muscle fibers contained within the perimysium |
| Endomysium | layer of areolar connective tissue that surround an individual muscle fiber |
| Myosatellite Cells | capillaries that bring nutrients to the fiber and muscle stem cells |
| Sarcolemma | cell membrane of the muscle |
| Sarcoplasm | cytoplasm of muscle |
| Glycosomes | vesicles containing glycogen |
| Myoglobin | similar in function to hemoglobin |
| Sarcomere | functional unit of the muscle; smallest contractile unit of the muscle |
| Myofilaments | thick filaments of myosin and thing filaments of actin |
| A-Band | darkest band where actin and myosin overlap; equal to the length of the myosin filament |
| H-Band | lighter than A-band; middle part of myosin that doesn't overlap with actin |
| I-Band | lightest band; part of actin which doesn't overlap with myoisin |
| Z-Line | structural protein which anchors actin |
| M-Line | holds myosins in register |
| Thing Filaments | composed of F-actin and 300-400 G-actins )globular proteins) |
| Nebulin | protein which maintains the position of G-actin |
| Tropomyoisin | double stranded protein that covers the active site of each G-actin |
| Active Site | site where actin binds to myosin |
| Troponin | formed by 3 globular subunits, T, I, and C |
| Tail | attached to the M line |
| Head | composed of two globular subunits; site of contact between the thin and thick filaments |
| ATPase | enzyme that catalyzes the decomposition of ATP to ADP |
| Hinge | connects tail to head |
| Titin | elastic filament associated with the thick filament, helps the muscle spring back after contraction |
| Sarcoplasmic Reticulum | equivalent of smooth endoplasmic reticulum in other cells; |
| Terminal Cisternae | expansion of SR in proximity of the I and A band junctions |
| Calsequestrin | protein that reversibly binds to CA within the terminal cisternae |
| Transverse Tubules | tubes contiguous with the sarcolemma and invaginate within the sarcoplasm |
| Triad | formed by a pair of terminal cisternae and a t-tubule |
| Neuromuscular Junction | synapses between a somatic motor neuron and a skeletal muscle cell |
| motor end plate | region of the sarcolemma at the NMJ |
| Alpha motor neuron | cell body located in the ventral horn of the gray matter of the spinal cord |
| End Plate Potentials | EPSP depolarization of the motor end plate |
| Excitation-Contraction coupling | sequence of events by which transmission of an action potential leads to sliding of myofilaments |
Created by:
rlmurp09
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