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Averse reactions associated with any category of diuretics: CARDIOVASCULAR: Orthostatic Hypotension, Electrolyte Imbalances DERMATOLOGIC: Rash and Photosensitivity
Diuretic Contraindications Mannitol: (an osmotic diuretic) ^ ICP Potassium Sparing Diuretics: hyperkalemia
Diuretic Interactiona Antihypertensive drug use with diuretics -> hypotension If hypokalemia is present, diuretics -> digoxin toxicity
Loop Diuretics Furosemide (Lasix)
Bumetanide (Bumex) Diuretic may cause electrolyte imbalances, photosensitivity, hypotension
Furosemide (Lasix) Diuretic Ototoxicity
Osmotic Diuretics Create diuresis by increasing blood osmolality which attracts fluid from other compartments (third spacing, cerebral fluid, intraocular) Used to decreased intracranial pressure (ICP) and (IOP)
Mannitol (Osmitrol) Cerevrak edema, Decreased ICP, Monitor Strict Input and Output
Potassium Sparing Diuretics (sodium and water retention) which results in potassium retention
Triamterene (Dyrenium) both drugs decrese excretion of potassium
Sprinolactone (Aldactone) antagonizes the action of aldosterone Hypokalemia, prophylaxis of hypokalemia * may cause hyperkalemia, gynecomastia: man boobs
Amiloride prevention of hypokalemia
Triamterene (Dyrenium) prevention of hypokalemia, may cause hyperkalemia
Thiazides and Related Diuretics Promotes diuresis when renal function is not imapaired Often medications of first choice for essential hypertension
Thiazides Chlorothiazide (Diuril) Hydrochlorithiazide (HCTZ)
Diruetecs: The client with increased intracranial pressure: Inspect Mannitol: solution for crystals Monitor: Urine output/hourly, B/P, P, R every 30-60min. , *Neurological assessments
Diuretics: Client risk for Hypokalemia Monitor clients on potassium-sparing diuretics for hyperkalemia
Diretics: Warning signs of fluid and electrolyte imbalance: Dry Mouth, thirst Weakness, lethargy, confusion Restlessness, muscle pains or cramps GI disturbances, oliguria Hypotension, tachycardia Seizures
Electrolyte Imbalance: Hyponatremia Confusion
Electrolyte Imbalance: Hypokalemia Muscle Cramps
Electrolyte Imbalance: Hyperkalemia Parathesias, muscle weaknes, flaccid paralysis
Diuretics: Client Education: Take drug with food or milk if GI upset occurs Take the drug early in the morning
Created by: yyolanda