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Campbell ch. 17
Chapter 17 gene to protein
| Term | Definition |
|---|---|
| gene expression | the process by which DNA directs the synthesis of proteins. |
| transcription | the synthesis of RNA using information from DNA |
| mRNA | carries a genetic message from the DNA to the ribosome. |
| translation | the synthesis of a polypeptide using the information in the mRNA. Change in language, from nucleotides to amino acids. |
| ribosome | site of translation. complex particles that facilitate the orderly linking of amino acids into polypeptide chains. |
| template strand | The strand of DNA 3' to 5' contains the pattern for the RNA to transcribe |
| codons | nucleotide sequences, 3 at a time. customarily written 5' to 3' |
| RNA polymerase | enzyme that separates the two strands of DNA apart and joins together RNA nucelotides, which elongates the RNA polynucleotides. |
| promoter | area where RNA polymerase binds and initiates transcription. |
| transcription factors | a collection of proteins that mediate the binding of RNA polymerase and the initiation of transcription. (p53) |
| TATA box | promoter DNA sequence, allows the RNA polymerase to bind to the strands |
| 5' cap | attaches to the 5' end |
| poly A tail | attaches to the 3' end. |
| poly A tail and 5' cap | help the mRNA to leave the nucleus in eukaryotic cells, protects from DEGRADATION and also helps the ribosome bind. |
| intron | non-coding region of nucleic acid that lie between coding regions |
| exon | eventually expressed by being translated into amino acid sequences. |
| spliceosome | interacts with certain sites along the intron, releasing the intron which degrades it joining the two exons. |