Save
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

anticoagulant

clinical med quiz

QuestionAnswer
inhibits synthesis of vitamin K dependent clotting factors by the liver that stimulate prothrombin production coumadin
activates antithrombin which indirectly blocks thrombin -made from pig or bovine mucosa heparin
thrombin inhibitor, processed heparin, chemically consistent lovenox
INDIRECTLY inhibits factor Xa arixtra
DIRECTLY inhibit factor Xa xarelto
direct thrombin inhibitor pradaxa
prevent platelets from clumping together to form a clot by various mechanisms antiplatelets
inhibits an enzyme that causes platelet clumping aspirin (NSAIDS)
inhibits two enzymes that cause platelets to clump aggrenox
used only in the hospital as part of combination therapy for acute coronary disease monoclonal antibodies / glycoprotein inhibitors: ReoPro, Integrilin, Aggrastat
block ADP receptors on the platelet surface to prevent clumping Thienopyridines: ticlid, plavix, effient
can cause coagulation disorders Thienopyridines: ticlid, plavix, effient
plavix effect can be reduced by PPI's Thienopyridines: ticlid, plavix, effient
dont dissolve clots dont thin blood anticoagulants
work by interfering with the bodys ability to clot by reducing the activity of certain proteins (clotting factors) anticoagulants
given to prevent clotting or treat existing clots by stabilizing them & preventing embolisms anticoagulants
monitor PT & INR coumadin
takes 96+ hrs for onset of action coumadin
therapeutic ranges: 2-3 for most 2.5 -3.5 for higher risk (valves, MI) coumadin
if > 4.0 high bleeding risk & no more therapeutic benefit coumadin
given orally coumadin & xarelto
reversed by vitamin K or fresh frozen plasma coumadin
unpredictable blood levels & highly individual response heparin
requires frequent monitoring of aPTT heparin
risk of HIT when body form antibodies against, check platelets heparin
given IV or SQ heparin
reversed by protamine heparin
MORE predictable plasma levels & therapeutic response lovenox
longer half-life so can be given daily or BID lovenox
monitoring PTTs is not needed or accurate lovenox
given SQ lovenox & arixtra & heparin
partially reversed by protamine lovenox
predictable plasma levels & therapeutic response arixtra & xarelto
do not require lab monitoring arixtra & xarelto & lovenox
monitor platelets arixtra & heparin
no antidote, may need dialysis arixtra & pradaxa
has to be taken twice daily pradaxa
no lab monitoring possible pradaxa
dangerous due to no reversal agent & delayed recovery of normal clotting, wait it out pradaxa
Created by: pgrams19
Popular Nursing sets

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards