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BMS resp. meds
| Term | Definition |
|---|---|
| Albuterol (type & trade name) | Short acting Beta2 Agonist; Proventil, Ventolin |
| Levabuterol (type & trade name) | Short acting Beta2 Agonist; Xopenex |
| Salmeterol (type & trade name) | Long acting Beta2 Agonist; Serevent |
| Formoterol Fumarate (type & trade name) | Long acting Beta2 Agonist; Foradil Aerolizer |
| ipratropium (type & trade name) | Cholinergic Antagonist; Atrovent |
| tiotropium (type & trade name) | Cholinergic Antagonist; Spiriva |
| theophylline (type & trade name) | Methylxanthine; Theo-Dur, Uniphyl, Theolair, Elixophyllin |
| aminophylline (type & trade name) | Methylxanthine; Truphylline |
| fluticasone (type & trade name) | inhaled corticosteriod; Flovent |
| budesonide (type & trade name) | inhaled corticosteroid; Pulmicort |
| nedocromil (type & trade name) | inhaled anti inflammatory; Tilade |
| Cromolyn (type & trade name) | Mast cell stabilizer; Intal *one of the fastest to treat asthma |
| omolizuman (type & trade name) | monoclonal antibody; Xolair |
| montalukast (type & trade name) | leukotriene antagonist; Singulair |
| zileuton (type & trade name) | leukotriene antagonist; Zyflo |
| 3 bronchodilators | Beta2 agonists, cholinergic antagonist, & methylxanthine |
| short acting Beta2 agonists side effects (2) | tachycardia w/ too much use; dry mouth/ throat |
| how do bronchodilators work | stimulate beta2 adrenergic receptor allowing smooth muscle of bronchi to relax |
| how cholinergic antagonist work | block parasympathetic nervous system so sympathetic nervous system takes over= bronchodilation & decrease pulmonary secretions |
| s/s of toxicity for methylxanthines (4) | tachycardia, N/V/D, restless, dysrhytmias *caffeine potentiates these symptoms |
| 5 anti inflammatory meds | corticosteroids, leukotriene antagonist, inhaled anti inflammatory, mast cell stabilizers, monoclonal antibodies |
| how corticosteroids work | decrease inflammation by PREVENTING synthesis of mediators |
| how inhaled anti inflammatory works | INHIBITS RELEASE of inflammatory mediators |
| how mast cell stabilizers work | prevent mast cell membrane from opening when an allergen bind to IgE |
| how monoclonal antibodies work | binds w/ IgE receptor site on mast cell & basophil, preventing allergens from releasing mediators from mast cell & basophils |
| how leukotriene antagonist works | prevent leukotriene synthesis OR block leukotriene receptor |
| what should you monitor on pt taking singulair | Liver function |
| Medications for Pneumonia (5) | Ticarcillin, Azithromycin, Levofloxacin, Ciprogloxacin, Vancomycin |
| guaifenesin (type & trade name) | mucolytic; Robitussin |
| acetylcysteine (type & trade name) | mucolytic; Mucomyst, Mucosil |
| what do mucolytics do | reduces viscosity (thickness) of secretions by increasing respiratory tract fluids -mobilization & expectoration of mucous |
| IV loading dose for Theophylline | 5-6 mg/ kg |
| PO loading dose for Theophylline | 5 mg/ kg |
| common side effects for Theophylline | restless, tremors, tachycardia, heart burn, headache, mild diuresis, insomnia, nausea, momentary change in sense of smell (IV) |
| serious side effects when giving Theophylline too rapidly IV | hypotension, fainting/ light headed, palpitations, tachycardia, hyperventilation, N/V, angina- like pain, seizures, cardiac standstill |
| what to monitor on pt taking Theophylline (5 things) | Respirations (rate, rhythm, depth), Heart (rate & rhythm, lung sounds, ABGs, cyanosis |
| things to teach pt for Theophylline (3) | Avoid caffeine, stop smoking, increase fluid intake |
| PO Albuterol dose | 2-4 mg 3-4 times per day |
| Inhalation Albuterol dose | 1-2 inhalations q4-6 hours |
| Nebulization Albuterol dose | 2.5- 10 mg q1-4 hours PRN |
| common side effects for Albuterol | headache, nausea, tremors, restless, dizzy, throat dryness, pharyngitis, BP changes/ hypertension, heartburn, transient wheezing, unusual/ bad taste or smell change |
| serious side effects of Albuterol | palpitations, extra heart beats, tachycardia, chest pain, BP change- high then low, |
| monitor on pt taking Albuterol | respirations (rate, depth, rhythm), heart (rate, rhythm), breath sounds, ABGs, Potassium |
| things to teach pt on Albuterol | how to use inhaler correctly, avoid caffeine, do not take more than 2 inhalations at one time, mouth dryness/ irritation can be diminished by rinsing mouth with water ASAP after inhalation |