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lab animals history

Names

QuestionAnswer
there were cravings on the wall. More diagrams of dissection and castrations of young boys Egyptian Pharoahs
responsible for Hippocratic oath for the doctors to do no harm. First person to realize cleanliness and sterility for surgery . Created operation room, table (raised or elevated) importance of putting it at adequate light Hippocrates
Did many different animal dissections. Discovered significance anatomical differences. First to perform operations and tests. Wrote three different type of books called Generation of Animals, History of Animals, and Parts of Animals. Aristotle
Dissections of different parts of species and did them in public Erasistratus
From the Dark century. Greek physician in Rome. First person to require living experiments on live animals. Galen
First person to describe circulation of blood. His college – they suggested to do animal surgery before doing it on people for better results Ibn al-Nafis
Anatomist- performed in depth human dissection. Wrote a book called the Structure of the Human Body also a professor at a university. Encouraged all physicians to do human dissections. Velasius
published the book “the movement of the heart and blood” real thorough description of circulation 60% to 70% is accurate. Sir William Harvey
published manuscript describing first ever intravenous injection. Used feather quills as a needle and gave iv injections to a dog’s heart. Wren
First ever to measure blood pressure on a horse. Blood pressure changes. Stephen Hales
Published paper – lungs is a pneumatic organ with air Bordeau
founder of experimental physiology in France Claude Bernard
founder of microbiology. Idea of germ theory of meds Louis Pastuer
. Laughing gas – nitric acid (no pain). Looked for other anesthetics such as ether. The gas absorbed to the blood to brain, depressing the nvs. 100% general anesthesia no pain! Rapid recover. Called a fraud John Morton
chrolyphly had similar properties of the ether: chloroform. James Simpson
first to grad vet school Cornell. Stayed as professor. GI system. Discovered mechanism of Salmonella. Justified the use of animals in meds. Most vocal component to say they need live animals D. E. Salmon
anti-toxin for diphtheria. Did a lot of work with Tetanus. Mechanism of action of how Tetanus is transmitted. Developed a vaccine for Bovine turbacillosis. Effective in cows developed a similar vaccine for humans: failed Emil von Behring
finding fountain of youth. Aging men to animals > castration. Changes association to age. First steroid abuser. If castrated animals lose male things – collected the testes and injected hisself with the testosterone. Brown-Sequard
was very first vet hired for lab animals in male clicnics. Lab animals were more commonly used. what the housing, feeding. Made a plan for how to keep them in the lab (mice, dogs) Simon D. Brimhall
studied diabetes used dos as model found out that if they had that diabetes: he collected pancreas. Lack of pancreas developed diabetes. From regular dogs put it on diabetic dogs it overcame the diabetes Banting & Best
Found Streptomycin antibiotic. Was the first to ever to affect human turbolictosis. Developed 20 different antibiotics. Made the term antibiotics. Selman Waksman
Developed the polio vaccine. Regular lab animals failed. First to use: Monkeys more similar to humans. Allowed success learned how to breed, survive and live them. Using cultured reeses monkeys tissue source of vaccine 1955 in public Jonas Salk
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