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MedSurge-KIDNEY
MedSurge-KIDNEY INJURY/DISEASE review
| Question | Answer |
|---|---|
| Prerenal, acute kidney injury(AKI) characteristics? | ↓ cardiac output, initial cause of most acute renal failure, hypovolemia, renal vascular obstruction, anaphylaxis |
| Intrarenal, acute kidney injury(AKI) characteristics? | tubular obstruction by myoglobin, nephrotic drugs, acute glomerulonephritis |
| Postrenal, acute kidney injury(AKI) characteristics? | mechanical outflow obstruction, prostate cancer, renal stones, bladder cancer |
| Acute tubular necrosis results primarily from? | renal ischemia and nephrotoxic injury & necrosis |
| Renal ischemia leads to acute tubular necrosis by disrupting the? | basement membrane |
| AKI, staging acronym? | RIFLE - Risk / Injury / Failure / Loss / End-Stage Kidney Disease |
| Reversal of oliguria occurs with fluid replacement in pt. with? | prerenal oliguria |
| Urine in prerenal oliguria content? | high specific gravity, low sodium concentration |
| Urine in intrarenal oliguria content? | low specific gravity, low high concentration |
| Urine specific gravity consistently 1.010 and osmolality @ 300 mOsm/kg is about the same as ___ and indicates _____? | plasma; tubules are damaged and unable to concentrate urine |
| Because the kidneys cannot synthesize ammonia needed to excrete H+, ____ ____ occurs. | metabolic acidosis |
| Characteristics of acute renal failure include? | urinary output of 3 - 5 L/day, ↓ Na+ / K+ levels, and fluid weight loss |
| S/S of AKI in the oliguric phase? | muscle weakness and abdominal cramping due to hyperkalemia, urine output @ 300mL/day, peripheral edema |
| Cardiac conduction abnormalities in oliguric phase include | peaked T waves, depressed ST segment, prolonged PR and QRS intervals |
| Most common cause of death in AKI is? | infection |
| During catabolism of body protein serum urea? | increases |
| Calcium-phosphorus imbalances in chronic kidney disease (CKD) results from? | deficiency of active VitD and high phosphorus levels |
| Calcium-phosphorus imbalances can lead to? | bone remodelling and weakened bone matrix |
| Aluminum accumulation is believed to contribute to? | osteomalacia |
| Osteitis fibrosis involves? | replacement of Ca in the bone with fibrous tissue, resulting from increased levels of parathyroid hormone from hypocalcemia |
| An appropriate snack for CKD? | hard candy |
| The syndrome that includes all S/S seen in various body systems in CKD is? | uremia |
| Azotemia is? | an elevation of blood urea nitrogen (BUN) and serum creatinine levels |
| Characteristics of hemodialysis? | requires vascular access, lowers serum triglycerides, intensified anemia, repaid fluid and creatinine loss |
| Characteristics of peritoneal dialysis? | increased hyperlipidemia, portable system, less cardio stress, more protein loss, fewer dietary restrictions |
| The dialysate for peritoneal dialysis contains? | dextrose in a higher concentration than in blood |
| Phases of peritoneal dialysis? | fill(inflow), dwell, drain |
| Temporary catheters vascular access site, characteristics? | usually used for access for continuous renal replacement therapy, most prone to infection |
| Native AV fistula, characteristics? | least likely to thrombose, 4 - 6 weeks healing time |
| Arteriovenous (AV) graft, characteristics? | 2 - 4 weeks healing time, may lead to distal ischemia |
| Evaluation of patency of an AV graft is performed by? | auscultating for the presence of bruits at the site |
| The most common indication for continuous renal replacement therapy is? | fluid overload |
| A major contraindication to kidney transplant is? | extensive vascular disease |