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Genes & DNA & RNA

Freshman Honors Biology - The Human Genome BioTechnology Protein Synthesis & RNA

QuestionAnswer
RNA ribonucleic acid; a natural polymer that is present in all living cells and that plays a role in protein synthesis
transcription the process of forming a nucleic acid by using another molecule as a template; particularly the process of synthesizing RNA by using one strand of DNA as a template
translation the portion of protein synthesis that takes place at ribosomes and that uses the codons in mRNA molecules to specify the sequence of amino acids in polypeptide chains
protein synthesis the formation of proteins by using information contained in DNA and carried by mRNA
ribose a 5-carbon sugar present in RNA
mRNA messenger RNA; a single-stranded RNA molecule that encodes the information to make a protein
rRNA ribosomal RNA; an organelle that contains most of the RNA in the cell and that is responsible for ribosome function
tRNA transfer RNA; an RNA molecule that transfers amino acids to the growing end of a polypeptide chain during translation
RNA polymerase an enzyme that starts (catalyzes) the formation of RNA by using a strand of a DNA molecule as a template
termination signal a specific sequence of nucleotides that marks the end of a gene
genetic code the rule that describes how a sequence of nucleotides, read in groups of three consecutive nucleotides (triplets) that correspond to specific amino acids, specifies the amino acid sequence of a protein
codon in DNA, a three-nucleotide sequence that encodes an amino acid or signifiesa start signal or a stop signal
anticodon a region of tRNA that consists of three bases complementary to the codon of mRNA
genome the complete genetic material contained in an individual
euchromatin a region of DNA that is uncoiled and undergoing active transcription into RNA
intron a segment of a strucural gene that is transcribed but not translated
exon in a structural gene, one of the segments that are ultimately transcribed and translated when the gene is expressed
pre-mRNA a precursor mRNA; the first strand of mRNA produced by gene transcription that contains both introns and exons
transcription factors regulatory proteins that bind to DNA and stimulate the transcription of certain genes
enhancers DNA sequences that recognize certain transcription factors that can stimulate transcription of nearby genes
length polymorphisms variations in the length of the DNA molecule between known genes
variable number tandem repeats (VNTR) sequences of DNA that repeat many times in tandem
polymerase chain reaction (PCR) a scientific technique that quickly produces copies of a DNA fragment
primers artificially made pieces of single-stranded DNA that are 20 to 30 nucleotides long that must be present for DNA polymerase to initiate replication
restriction enzymes bacterial proteins that recognize specific short DNA sequences, and cu the DNA in or near the sequence
gel electrophoresis technique that separates nucleic acids or proteins according to their size and charge
DNA fingerprint the pattern of bands that results when an individual's DNA sample is radiolabeled and exposed to X rays after being fragmented, replicated, and separated
genetic engineering a technology in which the genome of a living cell is modified for medical or industrial use
recombinant DNA DNA molecules that are artificially created by combining DNA from different sources
plasmid a circular DNA molecule that is usually found in bacteria and that can replicate independent of the main chromosome
clone an exact copy of a DNA segment, a whole cell, or a complete organism
vector DNAs that can replicate within a cell and carry foreign DNA
probe strand of RNA or single-stranded DNA that is labeled with a radioactive element or fluorescent dye and that can base-pair to specific DNA, such as the donor gene in recombinant DNA
Human Genome Project research effort undertaken to sequence all of our DNA and locate within it all of the functionally important sequences, such as genes
proteome an organism's complete set of proteins
single nucleotide polymorphisms (SNP) unique spots where individuals differ by a single nucleotide
bioinformatics a combination of biological science, computer science, and information technology used to enable the discovery of new biological insights and unifying principles
proteomics study of all of an organism's proteins, including their identities, structures, interactions, and abundances
two-dimensional gel electrophoresis a method that separates the proteins in a sample into individual spots
gene therapy a technique in which a genetic disorder is treated by introducing a gene into a patient's cells
cloning by nuclear transfer procedure in which a nucleus from a body cell is introduced into an egg cell to generate an organism identical to the nucleus donor
telomeres repeated DNA sequences at the ends of chromosomes that shorten with each round of cell division
DNA vaccine a vaccine made from the DNA of a pathogen but does not have disease-causing capability
bioethics the study of ethical issues related to DNA technology
Created by: xox.saras.xox
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