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Bio Chapter 6

Test 2

QuestionAnswer
tumor mass of cells with no function
metastatic cells can travel throughout the body via the.. circulatory system or the lymphatic system
lymphatic system collects fluid that leaks from capillaries
cancer cells differ from normal cells... 1) they divide when they shouldn't 2) invade surrounding tissues 3) move to other locations in the body
risk factors for cancer tabacco/alcohol use
asexual reproduction -offspring are identical to the original cell or organism -involves inheritance of all genes from one parent
sexual reproduction -offspring are similar to parents, but show variations in traits -involves inheritance of unique sets of genes from two parents
duplicated chromosomes are held together at the: and are called: centromere sister chromatids
chromatin DNA wraps around histone proteins
semiconservative replication two identical daughter molecules, each with one parental strand and one new strand
DNA polymerase the enzyme that replicates DNA
mitosis the division of the genetic material in the nucleus
cytokinesis the division of the cytoplasm
meiosis gametes are produced by a variation of the cell division
meiosis yeilds: nonidentical daughter cells that have only one set of chromosomes, half as many as the parent cell
three stages of the cell cycle 1)interphase 2)mitotic phase 3)cytokinesis
mitotic spindle composed of microtubules produced by centrosomes
centrosomes structures in the cytoplasm that: -organize microtuble arrangement -contain a pair of centrioles in animal cells
aster a radial array of short microtubules that extends from each centrosome
mitosis -prophase -metaphase -anaphase -telophase
cytokinesis division into separate cells
mutation change in the sequence of DNA
proto-oncogenes genes that enable cells to regulate cell division
oncogenes normal proto-oncogenes that have mutated
tumor suppressor genes genes for proteins that stop cell division if conditions are not favorable
angiogenesis tumor gets it's own blood supply
contact inhibition cells do not like to pile on each other
anchorage dependence loss of this enables a cancer cell to move to another location
immortalized cells no longer have a fixed number of cell divisions
multiple hit model process of cancer development requires multiple mutations
biopsy surgical removal of cells or fluid for analysis
needle biopsy removal is made using a needle
laparascope surgical instrument with a light, camera, and a small scalpel
chemotherapy drugs that selectively kill dividing cells
radiation therapy use of high-energy particles to destroy cancer cells
clone a group of genetically identical individuals from the same parent
somatic cell any cell other than a gamete
humans have __ pairs of chromosomes 23
__ pairs of autosomes 22
__ pair of sex chromosomes 1
locus position of a gene
meiosis a specialized form of cell division in gonads to produce gametes
gametes are: somatic cells are: haploid diploid
meiosis beings with interphase
recombinant chromosomes combine DNA inherited from each parent
chiasma the site of attachment and crossing over
random alignment each pair of chromosomes sorts maternal and paternal homologues into daughter cells independently of the other pairs
nondisjunction failure of chromosomes or chromatids to separate during meiosis
trisomy 21 involves the inheritance of three copies of chromosome 21
Adults produce ____ in their ____ by _____ gametes, gonads, meiosis
Zygote sperm cells fertilize egg cells to form single-celled zygotes
embryo formed by repeated cell divisions
fetus what the embryo grows into
genes segments of DNA that code for proteins, analogous to words in an instruction manual for building a human
chromosomes analogous to pages in the instruction manual
mutations mistakes in copying DNA
alleles different versions of genes
segregation in meiosis, one member of each homologous pair goes into a gamete
independent assortment randomly determines which member of a pair of chromosomes goes into a gamete
random fertilization produces more diversity: 64 trillion possibilities!
monozygotic twins only two humans that are genetically identical
phenotype physical traits of an individual
genotype description of the alleles for a particular gene in an individual
homozygous both alleles for a gene are identical
heterozygous the gene has two different alleles
recessive the phenotype of an allele is seen only when homozygous
dominant the phenotype is seen when homozygous or heterozygous
cystic fibrosis a recessive human genetic disease
heritability proportion of the variation within a population due to genetic differences among individuals
mean sum up all the phenotypic values and divide by the number of individuals, same as average
variance a measure of how much variability there is in the population
polygenic traits quantitative traits with continuous variation
polygenic inheritance skin color is affected by at least three genes
artificial selection ex. only the cow giving the most milk was allowed to breed
high heritability likely to be inherited
natural experiments situations in which either the overlap in genes or environment is removed
incomplete dominance two copies of the dominant allele are required to see the full phenotype
codominance neither allele is dominant to the other; heterozygote shows both traits at once
multiple allelism more than two alleles found in the population
Rh factor (completely dominant) positive: you have Rh factor negative: you do not have Rh factor
pleiotropy one gene influencing many characteristics
hemophilia the inability to clot blood normally due to the absence of a clotting factor
sex-linked genes genes located on the sex chromosomes
X-linked located on the X chromosome
Y-linked located on the Y chromosome
X-linked recessive traits only females can be carriers of
Barr body early female embryos randomly inactivate one of the X chromosomes in each cell
pedigree reveals modes of inheritance
PCR polymerase chain reaction in DNA fingerprinting
how to fingerprint DNA DNA is mixed with nucleotides, specific primers, Taq polymerase, and then is heated
restriction enzymes what DNA is cut into fragments using
VNTR (variable number tandem repeats) cut around DNA sequences
gel electrophoresis separates DNA fragments on basis of their sizes
agarose gel electric current is applied to
probs reveal locations of fragments containing VNTRs
Created by: copage
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