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Lecture 4
Lecture 4: Action Potential
| Question | Answer |
|---|---|
| Membrane Potential | differences in electrical charges between the inside and outside of the cell membrane |
| Depolarization | membrane potential becomes more positive |
| Hyperpolarization | membrane potential becomes more negative |
| Ionotropic Receptors | ligand binds to a protein which changes conformation opening a channel allowing one or more ions to pass through it |
| Graded Potential | local change of membrane potential resulting from a stimulation |
| EPSP | excitatory post synaptic potential, depolarizing graded potential |
| IPSP | inhibatory post synaptic potential, hyperpolarizing graded potential |
| Spread of Depolarization | local currents created depolarize adjacent membrane areas and allow the wave of depolarization to spread |
| Longitudinal Resistance | created by the cytoplasm which resists the spread of current |
| Transverse REsistance | positive charges that enter the cell will leave it through the leakage channels |
| Action Potential | brief reversal of membrane potential |
| Absolute Refractory Period | 1 ms, sodium channel inactivated, no stimulus no matter how intense can generate another AP |
| Relative Refractory Period | depends on the outward movement of potassium, sodium channels are closed but a strong stimulus can generate and AP |
| Nodes of Ranvier | segments of the axon where there is no myelin |