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Pharmacology Nurses

Chapter 22 Drugs for Lipid Disorders

Three Types of Lipids Triglycerides, Phospholipids, Steroids
Cholesterol 1.The most widely known of the steroids 2.Promotes Atherosclerosis 3.Serves as the building block for a number of essential biochemicals, including vitamin D, bile acids, cortisol, estrogen, and testosterone. 4. Excretion via bile only way of removal.
Total Cholesterol < 200 = Desirable 200-239 = Borderline High Risk > 239 = High Risk
The American Heart Association recommends: less than 300 mg of dietary cholesterol per day.
Lipoproteins Lipid molecules are not soluble in plasma to transport the body forms complexes called lipoproteins, that have a protein carrier (apoprotein)
HDL (High Density Lipoprotein) (HAPPY) 1. contains the most apoprotein 2. manufactures in the liver and small intestine and assist in the transport of cholesterol away from the body tissues (reverse cholesterol transport) <40 = LOW 40-59= Borderline High Risk >60 = Desirable
LDL (Low Density Lipoprotein) (LAME) Contains the highest amount of cholesterol < 100 = desirable 100-129 = near above optimal 130-159 = Borderline high risk 160-189 = High Risk >190 = Very High Risk
VLDL (very Low Density Lipoprotein) Through a series of steps, VLDL is reduces in size to become LDL. is the primary carrier of triglycerides in the blood.
Hyperlipidemia High Levels of lipids in the Blood, a major risk of cardiovascular disease.
Hypercholesterolemia 1.Elevated blood cholesterol. 2.Type of Hyperlipidemia
Created by: nelcyoviedo