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Med immunology 1
| Question | Answer |
|---|---|
| ________ refers to all the mechanisms used by the body as protection against environmental agents that are foreign to the body. | Immunity |
| What are the four major subdivisions of immune systems? | Reticuloendothelial system, extracellular fluid, bloodstream, lymphatic system |
| What is: the network of connective tissue fibers that interconnects other cells and meshes with the connective tissue network surrounding organs and it is where phagocytic cells inhabit? | Reticuloendothelial system (RES) |
| What are two branches of immunity? | Innate, Adaptive |
| Which branch of immunity is specific immunity? | adaptive(acquired) |
| Which branch of immunity is non-specific? | Innate |
| What are first line of defense? | Physical(skin), Chemical(sweat, urine, tears etc), genetic barriers |
| ________ is a surface protection composed of anatomical and physiological barriers that keep microbes from penetrating sterile body compartments. | first line of defense |
| ________ is a cellular and chemical system that comes immediately into play if infectious agents make it past the surface defenses. | second line of defense |
| What are second line of defense? | inflammatory response, Interferons, Phagocytosis, Complement |
| ________ includes specific host defenses that must be developed uniquely for each microbe through the action of specialized white blood cells. | Third line of defense |
| What are third line of defense? | antibodies, T cells, accessory cells and cytokines |
| Which line of defense includes B-cell and T-cell? | Third line of defense |
| which line of defense is (are) under innate immunity? | First line and second line |
| Phagocytosis is ________ line of defense | second |
| skin is ______ line of defense | first |
| Which component of white blood cells is most abundant? | Neutrophils/maicrophage |
| Which components of white blood cells is least abundant? | basophil, mast cells |
| Which components of white blood cells contribute innate immunity? | neutrophils, eosinophils, basopils, mast cells, monocytes(macrophages) |
| which component of white blood cells contribute adaptive immunity? | lymphocytes |
| what is the other name of secondary response? | anamnestic response |
| what is the biggest difference between innate and adaptive immunity? | memory |
| what trigger specific immune responses? | antigens |
| which lymphocytes are involved in Humoral immunity? | B cells |
| Which lymphocytes are involved in cell mediated immunity? | T cells |
| Which lymphocytes produce antibodies? | B cells |
| Which lymphocytes directly attack the foreign entity? | T cells |
| What substances constitute antigens? | components of bacterial cell walls, capsules, pili, flagella, proteins of viruses, fungi, protozoa, food and dust |
| _________ is also called immunoglobulins, and soluble proteins that bind antigen. | antibody |
| Millions of antibodies are produced by a complex genetic recombinational mechanism called ______________. | Clonal Selection |
| Upon contact with antigens, B cells become active and produce __________, _________. | Plasma cells, memory cells |
| __________ produce antibodies. | plasma cells |
| Antigen-binding sites are also called ___________. | variable region |
| What are two types of acquired immunity? | naturally acquired, Artificially acquired |
| Which acquired immunity is this? "acquired through the normal life experiences not induced through medical means" | natural immunity |
| Which acquired immunity is this? is that produced purposefully through medical procedures. also called immunization)" | Artificial immunity |
| What type and subtype of immunity? "the consequence of a person developing his own immune response in microbe when the person is exposed to a particular pathogen" | Natural active immunity |
| What type and subtype of immunity? "the consequence of one person receiving preformed immunity made by another person. For example, breast feeding." | Natural passive immunity |
| What type and subtype of immunity? "consequence of a person developing his own immune response to a microbe after vaccination" | Artificial active immunity |
| What type and subtype of immunity? "occurs when one person receives preformed immunity made by another person, like injecting antibodies produced by other person" | Artificial passive immunity |
| What is called when the body produces antibodies and cytotoxic T cells that target normal body cells? | autoimmunity |
| List examples of autoimmune disorders | Systemic lupus erythematosus, Pheumatoid arthritis, Pheumatic fever, Type1 diabetes, Glomerulonephritis, Multiple Sclerosis |