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NPB 101

Lecture 3

QuestionAnswer
What are fenestrated arteries? Arteries with small pores in them that let small ions diffuse freely through the walls
What are the two ways that materials can leave the fenestratd arteries? Lipid-soluble materials can diffuse through the endothelial cell wall. Water-soluble material can diffuse through the fenestrated pores
How do materials leave the capilaries and reach the peripheral nerves? They go through the fenestrated capillary, then leak through the coverings around the axons and go into the extraceullular spaces
What two major arteries carry blood to the brains? The internal carotid artery in front of the bones of the neck, and the basilar artery on the sides of the bones in the neck
What happens two the two major arteries in the brain when they get to the brain? They branch out into arterioles and then into capillaries so that they can spread the blood evenly to the brain.
What is the blood brain barrier? The capillaries in the brain aren't fenestrated like they are lower in the body. Because of this no polar ions can enter or exit the brain through the pores. If an ion is soluble enough or has enough time it can diffuse through the endothelial membranes.
What are ventricles? A cavernous space in the brain that fills with a liquid that passes around the brain
How do polar ions diffuse into the CSF? The polar ions diffuse out of the fenestrated capillaries, which then diffuse across the choroid plexus. These ions then get taken into the cerebrospinal fluid (CSF)
What happens to the polar ions after they get into the CSF? They diffuse through connective tissues past the blood brain barrier into the extracellular fluid. This is the fluid immediately surrounding the cells of the brain.
Where does the cerebralspinal fluid go in the brain? Into the subarachnoid space in the brain between two layers of connective tissue. The arachnoid membrane and pia mater. This region travels around the brain and the spinal cord.
What happens if more cerebralspinal fluid is made then leaves the brain? A condition called hydocephaly, common name is water on the brain
How does cerebralspinal fluid leave the brain? It leaves the brain after making a full circulation around the brain and spinal cord it enters the superior sagittal sinusn via the villi and into the veinous blood.
What is the periphery? The fluid around the peripheral nerves
What do arteries break up into? Arteries break up into archaels which break up into capillaries
Created by: 24rory
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