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# Step 1 1.10.12

### Key Equations and Relations

QuestionAnswer
How do you calculate sensitivity? =TP/(TP+FN)
How do you calculate specificity? =TN(TN+FP)
How do you calculate positive predictive value? =TP/(TP+FP)
How do you calculate negative predictive value? =TN(TN+FN)
How do you calculate Relative risk? = [a/a+b]/[c/c+d]
How do you calculate attributable risk? =[a/a+b]-[c/c+d]
How do you calculate number needed to treat? 1/absolute risk reduction
How do you calculate number needed to harm? 1/attributable risk
How do you calculate Hardy Weinberg equilibrium? p^2 + 2pq+q^2= 1 p+q=1
How do you calculate the henderson Hasselbach equation for CO3 and CO2? pH=pKa+log[[HCO3-]/0.03 PCO2]]
How do you calculate volume of distribution? = amount of drug in body/plasma drug concentration
How do you calculate ? =rate of elimination of drug/plasma drug concentration
How do you calculate Half life? =0.7 x Vd/ CL (where Vd is volume of distorbution)
How do you calculate loading dose? LD=Cpx Vd/F
How do you calculate maintenance dose? MD= Cp x CL/F
How do you calculate Cardiac output? =rate of O2 consumption/ (arterial O2 content- venous O2 content)
How do you calculate cardiac output via SV? CO=SV x HR
How do you calculate mean arterial P? MAP=CO x total peripheral resistance. MAP= 1/3 systolic +2/3 distolic
How do you calculate dstroke volume? SV= End diastolic volume - end systolic volume
How do you calculate ejection fraction? EF=stroke volume/end diastolic volume x 100
How do you calculate resistance? =driving pressure/ flow= 8 (nu=viscosity) x length/pi r^4
How do you calculate Net filtration pressure? = [(Pc-Pi) - (pic-pii)]
How do you calculate glomerular filtration rate? GFR=U inulin cx V/P inulion= C inulin
How do you calculate glomerular filtration rate via osmotic forces? GFR= Kf[(Pgc-Pbs) - (piGC- piBS)]
How do you calculate effective renal plasma flow? ERPF= Upah x (V/Ppah) = Cpah
How do you calculate renal blood flow? RBF= RPF/(1-Hct)
how do you calculate the filtration fraction? FF=GFR/RPF
How do you calculate physiological dead space? Vd=Vt x [(PaCO2-PeCO2)/(PaCO2)]
Created by: tjs2123

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