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Step 1 1.9.13 (3)

Key Associations 2

QuestionAnswer
Key association: neoplasm in kids? 1.ALL 2. Cerebellar meduloblastoma
Key association: nephrotic syndrome adults? focal segmental glomerulosclerosis
Key association: nephrotic syndrome in kids? minimal change disease, (associated with infections/vaccinations; treat with corticosteroids)
Key association: neuron migration failure? Kallmann syndrome
Key association: nosocomial pneumonia? Klebsiella, E. coli, Pseudomonas aeruginosa
Key association: obstruction of male urinary tract? BPH
Key association: opening snap? mitral stenosis
Key association:opportunistic infections in AIDS? Pneumocystis jirovecii (used to be carinii) pneumonia
Key association: osteomyelitis? S. aureus
Key association: osteomyelitis in sickle cell disease? Salmonella
Key association: osteomyelitis w IV drug use? Pseudomonas, S. aureus
Key association: ovarian mets from gastric carcinoma or breast cancer? Krukenberg tumor (mucin secreting signet ring cells)
Key association: ovarian tumor (benign and bilateral)? serous cystadenoma
Key association: ovarian tumor malignant? serous cystadenocarcinoma
Key association: pancreatitis acute? gall stones, EtOH
Key association: pancreatitis chronic? EtOH (adults), CF in kids
Key association: Pt with ALL/CLL/AML/CML? ALL: child CLL:adult >60 AML: adult ~60 CML:adult 30-60
Key association: pelvic inflammatory disease? Neisseria gonorrhoeae (monoarticular arthritis)
Key association: philadelphia chromosome t(9:22) (bcr-abl)? CML (sometimes ALL/AML)
Key association: pituitary tumor? 1. prolactinoma 2. Somatotropic "acidophillic" adenoma
Key association: primary amenorrhea? turner syndrome (45 XO)
Key association: primary bone tumor in adults? multiple myeloma
Key association: primary hyperaldosteronism? adenoma of the adrenal cortex
Key association: primary hyperparathyroidism DDx? 1. adenomas 2. hyperplasia 3. Carcinoma
Key association: primary liver cancer? hepatocellular carcinoma ( chronic hepatitis, cirrhosis, hemochromatosis, alpha 1 antitrypsin)
Key association: pulmonaryHTN? COPD
Key association: recurrent inflammation/thrombosis of small/medium vessels in extremities? Buerger's disease (strongly associated with tobacco
Key association:Renal tumor DDx? Renal cell carcinoma: associated with von-Hippel Lindau and adult polycystic kidney disease; paraneoplastic syndromes (EPO, renin, PTH, ACTH)
Key association: RHF due to a pulmonary cause? cor pulmonale
Key association: S3 (protodiastolic gallop)? incr ventricular filling (L to R shunt, mitral regurgitation, LV failure [CHF])
Key association: S4 (presystolic gallop)? stiff/hypertrophic ventricle (aortic stenosis, restrictive cardiomyopathy)
Key association: secondary hyperparathyroidism? hypocalcemia of chronic kidney disease
Key association: STD? Chlamydia (usually coinfected with Gonorrhoeae)
Key association:SIADH? small cell carcinoma of the lung
Key association: site of GI diverticula? sigmoid colon
Key association: sites of atherosclerosis? abdominal aorta> coronary>popliteal>carotid
Key association: stomach cancer? adenocarcinoma
Key association: stomach ulceration and high gastrin levels? Zollinger-Ellison syndrome (gastrinoma of duodenum or pancreas)
Key association: t(14;18)? follicular lymphomas (bcl-2 activation)
Key association: t (8;14)? Burkitt's lymphoma (c-myc activation)
Key association: t(9;22)? philadelphia chromosome, CML (bcr-abl fusion)
Key association: temproal arteritis? risk of ipsilateral blindness due to thrombosis of ophthalmic artery; polymyalgia rheumatica
Key association: testicular tumor? seminoma
Key association: thyroid cancer? papillary carcinoma
Key association: tumor in women? leiomyoma (estrogen dependent, no precancerous)
Key association: tumor of infancy? hemangioma (usually regresses spontaneously by childhood)
Key association: tumor of the adrenal medulla in adults? pheochromocytoma (usually benign)
Key association: tumor of the adrenal medulla (kids)? meuroblastoma (malignant)
Key association:Type of Hodkin's? nodular sclerosis (vs mixed cellularity, lymphocytic predominance, lymphocytic depletion)
Key association: Type of non-Hodgkin's? diffuse large cell
Key association: UTI? E. coli, Staphylococcus saprophyticus (young women)
Key association: viral encephalitis affecting the temporal lobe? HSV-1
Key association:vitamin deficiency in US? folic acid (pregnant women, body only has 3-4 month supply, prevents neural tube defects)
Created by: tjs2123