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Pharm drugs

Prefix aand suffix of drugs

QuestionAnswer
-actone aldactone, spironolactone Potassium sparing diuretic.
-afil sildenafil (viagra); tadalafil (cialis); vardenafil (levitra) phosphodiesterase (PDE) inhibitor: augments effects of nitric oxide released during stimulation causing blood to corpus cavernosum for penile erection; for erectile dysfunction
-ane cyclohexane, ethane, flourane general anesthetics.
-artan ARB A2RB (angiotensin 2 receptor blocker) used for HTN.
-ase eminase, retavase, streptokinase thrombolytic (clot busters)
-asone betamethasone; dexamethasone; fluticasone; mometasone corticosteroid
-azosin doxazosin (Cardura), prazosin (Minipress), terazosin (Flomax,Alfuzosin (Uroxatral) alpha blocker; blocks receptors hormone norepinephrine (noradrenaline) in arteries & smooth muscle. Relaxes blood vessels increase blood flow & lower BP HTN, enhances urinary flow in prostatic hypertrophy (enlarged prostate). affinity to Mu receptor.
-azole butoconazole, econazole, fluconazole antifungal.
-bicin doxorubicin; epirubicin; idarubicin; valrubicin antineoplastic; cytotoxic agent
-barbital, -bital butabarbital; butalbital; phenobarbital; secobarbital, pentobarbital, amobarbital barbiturate (sedative, hypnotics)
-caine cocaine, bupivacaine; lidocaine; mepivacaine; prilocaine; proparacaine; xylocaine local anesthetic , numbing agent
-calci- calciferol, calcitrol, ergocalciferol calcium supplements with Vitamin D.
cef-, ceph- cefaclor; ceftibuten; cefdinir; cefadroxil; cefixime; cefprozil; cephalexin; cephraprin;cephradine cephalosporin antibiotic
-cillin amoxicillin; ampicillin; dicloxacillin; nafcillin; oxacillin penicillin antibiotic, for bacterial infection
-cort- (-olone, -sone) clocortolone; fludrocortisone; hydrocortisone corticosteroid
-cycline demeclocycline; doxycycline; minocycline; tetracycline tetracycline antibiotic, for bacterial infection
-dazole albendazole; mebendazole; metronidazole; tinidazole; nitroimidazole anthelmintic; antibiotic; antibacterial
-dipine amlodipine; felodipine; nifedipine; nimodipine; nisoldipine; isradipine calcium channel blocker: Reduces peripheral vascular resistance by systemic vasodilation.
-dronate alendronate; etidronate; ibandronate; risedronate bisphosphonate; bone resorption inhibitor
-eprazole esomeprazole; omeprazole; rabeprazole proton pump inhibitor (PPI)
-fenac bromfenac; diclofenac; nepafenac NSAID
-floxacin ciprofloxacin; levofloxacin; moxifloxacin; ofloxacin; gatifloxacin fluoro-quinolone antibiotics for bacterial infection broad spectrum, targets bacteria DNA gyrase and inhibits DNA synthesis
-gliptin saxagliptin; sitagliptin; linagliptin antidiabetic; inhibitor of the DPP-4 enzyme
-glitazone pioglitazone; rosiglitazone; troglitazone antidiabetic; thiazolidinedione
-ine amphetamine, caffiene, terbutaline, theophylline Stimulants
-iramine brompheniramine; chlorpheniramine; pheniramine antihistamine
-itidine H2 antagonist, used for allergies as histamine blocker; Blocks action of histamine on parietal cells in the stomach, decrease action production. Treats Dyspepsia. -lamide acetazolamide; brinzolamide; dorzolamide; methazolamide
-lax Exlax, Ducolax laxative; increases perstalsis stimunlating nerve in colon wall onset 15-60 minutes. induce bowel movement, loosen stool, treat constipation.
-mab adalimumab; daclizumab; infliximab; omalizumab; trastuzumab monoclonal antibody
-mustine carmustine; estramustine; lomustine; bendamustine alkylating agent (antineoplastic)
-mycin, -micin, -romycin azithromycin; clarithromycin; clindamycin; erythromycin; gentamicin antibiotic; antibacterial: ( -romycin: macrolide), aminoglycoside antibiotics
-nacin darifenacin; solifenacin muscarinic antagonist (anticholinergic)
-nazole, azole fluconazole; ketoconazole; miconazole; terconazole antifungal
-olol, -lol atenolol (tenormin); metoprolol; nadolol (corgard); pindolol; propranolol (inderal); timolol beta1 andrenergic blocker : binds B1 receptors in heart, arteries & arterioles block response sympathetic impulses ↓HR & CO by artery dilated. For HTN, arrhythmia, glaucoma & migraine brnkospasm & bradycardia)BP <90/60, Pulse <50 no admin, caution w/COPD
-olone fluocinolone; fluorometholone; prednisolone; triamcinolone corticosteroid
-olone nandrolone; oxandrolone; oxymetholone anabolic steroid
-onide budesonide; ciclesonide; desonide; fluocinonide; halcinonide corticosteroid
-oprazole, -prazole dexlansoprazole; lansoprazole; pantoprazole proton pump inhibitor (PPI), anti ulcer
-pam, benzo- diazepam, lorazepam Benzodiazepines (Benzos), anxiolytics: antidepressants for psych, treating sleep, sedation, anxiety, muscle spasms, prevent seizures
parin; -parin enoxaparin; fondaparinux; heparin; tinzaparin antithrombotic; anticoagulant (blood thinner)
-phylline aminophylline; dyphylline; oxtriphylline; theophylline xanthine derivative (bronchodilator)
-pramine clomipramine; desipramine; imipramine; trimipramine tricyclic antidepressant (TCA)
pred; pred- loteprednol; prednicarbate; prednisolone; prednisone corticosteroid, antiinflammatory
-pril benazepril (Lotensin); captopril (capoten); enalapril (vasotec); lisinopril (prinivil, zestril); moexipril; ramipril ACE1 inhibitor (angio converting enzyme inhibitor), lowers BP by blocking the conversion of angiotensin 1 to a-tensin II, prevents vasoconstriction, ↓aldosterone production & fluid retention, ↓circulating fluid volume,for HTN, CHF, CRF (renal failure).
-profen fenoprofen; flurbiprofen; ibuprofen; ketoprofen NSAID, antiinflammatory non selective: also COX 2 inhibitor celecoxib (celebrex)& oral/parental ketorolac (toradol)
-quine chloroquine, hydroxychloroquine, mefloquine antiparasitics.
-razole Proton pump inhibitor Reduces gastric acid production, used for GERD.
Rifa- rifamate, rifampin, rifapentine, rifater Antituberculars.
-sartan candesartan; irbesartan; losartan (cozaar); olmesartan(Benicar); valsartan angiotensin II receptor antagonist; ARB: angiotensin II receptor blocker: lowers BP by blocking the binding of angiotensin II which prevents vaso constriction.
-semide furosemide(Lasix); torsemide loop diuretic (water pill): lowers BP by reducing reabsorption of sodium and water by kidneys lowering circulating fluid volume: mobilizes edematous fluid reducing preload (pulmonary venous pressure).
-setron alosetron; dolasetron; granisetron; ondansetron; palonosetron serotonin 5-HT3 receptor antagonist
-setron dolasetron; granisetron; ondansetron; palonosetron antiemetic and antinauseant
-sone prednisone, cortisone, dexamethasone corticosteroids antiinflammatories
-statin, -vastatin atorvastatin; lovastatin; pravastatin; rosuvastatin; simvastatin HMG-CoA reductase inhibitor; statins lowers lipids & cholesterol
-stigmine neostigmine, physostigmine, pryridostigmine cholinergics
-stine carmustine, lomustine, vinblastine, vincristine antineoplastics:anti tumor.
sulfa-, sulf sulfacetamide; sulfadiazine; sulfamethoxazole; sulfasalazine; sulfisoxazole sulfonamides antibiotic; anti-infective; anti-inflammatory
-tadine cyproheptadine; desloratadine; loratadine; olopatadine antihistamine
-tadine amantadine; rimantadine antiviral; anti-influenza-A
-terol albuterol; arformoterol; formoterol; levalbuterol; salmeterol beta agonist; bronchodilators
-thiazide chlorothiazide; hydrochlorothiazide; methyclothiazide, benzthiazide thiazide diuretic (water pill); Potassium wasting diuretic; lowers BP by reducing reabsorption of sodium and water by kidneys lowering circulating fluid volume
-tidine cimetidine, famotidine, nizatidine, ranitidine H2 receptor antagonist (antiulcer agnet)
-tinib crizotinib; dasatinib; erlotinib; gefitinib; imatinib antineoplastic (kinase inhibitor)
-trel desogestrel; etonogestrel; levonorgestrel; norgestrel female hormone (progestin)
tretin-; tretin; -tretin acitretin; alitretinoin; isotretinoin; tretinoin retinoid; dermatologic agent; form of vitamin A
-triptan almotriptan; eletriptan; rizatriptan; sumatriptan; zolmitriptan, naratriptan, rizatriptan antimigraine; selective 5-HT receptor agonist
-tyline amitriptyline; nortriptyline; protriptyline tricyclic antidepressant (TCA)
vir; -vir abacavir; efavirenz; enfuvirtide; nevirapine; ritonavir; tenofovir antiviral; anti-HIV
vir; -vir adefovir; entecavir; ribavirin (along with interferon) antiviral; anti-hepatitis
-vir, -cyclovir acyclovir; famciclovir; penciclovir; valacyclovir antiviral; anti-herpes
-vir cidofovir; ganciclovir; valganciclovir antiviral; anti-CMV
-vir oseltamivir; zanamivir antiviral; anti-flu
-vudine lamivudine; stavudine; telbivudine; zidovudine antiviral; nucleoside analogues
-zepam, -pam clonazepam; diazepam; flurazepam; lorazepam; temazepam benzodiazepine
-azine chlorpromazine, perphenazine, prochlorperazine Phenothiazines (antipsychotics, antiemetics)
-zodone nefazodone, trazodone, vilazodone antidepressant
-zolam alprazolam; estazolam; midazolam; triazolam benzodiazepine
-zoline oxymetazoline (afrin, dristan, vicks, sinex visine LR, zicam, sudafed OM), zylometazoline topical OTC nasal decongestants is an alpha 1 agonist, partial alpha 2 agonist
-zosin alfuzosin; doxazosin; prazosin; terazosin alpha blocker
Created by: larue10510