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CCCC BIO107 Final

Human Anatomy & Physiology 1 Lecture Final

FRONTBACK
Skeletal Cartilage Characteristics -has no blood vessels or nerves -dense connective tissue of perichondrium contains blood vessels for nutrient delivery
3 Skeletal Cartilages 1. Hyaline cartilages 2. Elastic cartilages 3. Fibrocartilages
Hyaline cartilages -provide support, flexibility, resilience -most abundant type
Elastic cartilages -similar to hyaline BUT -contain elastic fibers
fibrocartilages -collagen fibers -have great tensile strength
2 types of cartilage growth 1. appositional 2. interstitial
appositional growth cells secrete matrix against the external face of existing cartilage
interstitial growth -chondrocytes divide and secrete new matrix -expands cartilage from within
Calcification of cartilage -"hardening" of cartilage -occurs during normal bone growth, old age
Classification of bones by location 1. axial (skull, vertebrae, ribs) 2. appendicular (appendages, girdles)
classification of bones by shape 1. long 2. short 3. flat 4. irregular
long bones + example -longer than they are wide -example: humerus, femur
short bones + example -cube-shaped (wrist/ankle) -sesamoid (within tendons) -example: cube-shaped (talus), sesamoid (patella)
flat bones + example -thin, flat, slightly curved -example: sternum
irregular bones + example -complicated shapes -example: vertebra
anatomy of long bone (2 components) 1. structures 2. membranes
structures of long bone 1. diaphysis (shaft) 2. epiphyses
diaphysis -shaft of long bone -compact bone surrounding medullary cavity -medullary cavity contains fat (yellow marrow)
epiphyses -expanded ends of long bone -spongy bone interior -has epiphyseal line -articular (hyaline) cartilage on joints
membranes of long bone 1. periosteum 2. endeosteum
periosteum -membrane of long bone -outer fibrous layer -inner osteogenic layer -nerve fibers, nutrient blood vessels, lymphatic vessels enter via foramina -secured by Sharpey's fibers
inner osteogenic layer -part of periosteum -contains 3 things 1. osteoblasts (bone building) 2. osteoclasts (bone destroying) 3. osteogenic cells (stem cells)
endosteum -delicate membrane on internal surfaces of long bone -contains osteoblasts and clasts
osteon system -aka haversion system -structural unit of compact bone
osteon system anatomy 1. lamellae 2. central/haversion canal 3. collagen fibers 4. Perforating/Volkmann's canals 5. Lacunae 6. Canaliculi
lamellae -part of osteon system -weight-bearing -column-like matrix tubes
Central (haversian) canal -part of osteon system -contains blood vessels and nerves
Perforating (Volkmann's) canals -part of osteon system -at right angles to central canal -connects blood vessels and nerves of periosteum and central canal
lacunae -part of osteon system -small cavities in osteon system that contain osteocytes
canaliculi -part of osteon system -hairlike canals -connect lacunae to each other and central canal
bone markings -bulges, depressions, and holes in bone
bone markings purpose -sites of attachment for muscles/ligaments/tendons -serve as joint surfaces -channels for blood vessels/nerves
bone marking projections purpose 1. sites of muscle/ligament attachment 2. projections that help to form joints
bone marking projections sites of muscle/ligament attachment 1 1. tuberosity (rounded projection) 2. crest (narrow, prominent ridge) 3. trochanter (large, blunt, irregular surface) 4. line (narrow ridge of bone)
bone marking projections sites of muscle/ligament attachment 2 5. tubercle (small rounded projection) 6. epicondyle (raised area above condyle) 7. spine (sharp, slender projection) 8. process (any bony prominence)
bone marking projections that help form joints 1. head (bony expansion carried on narrow neck) 2. facet (smooth, nearly flat articular surface) 3. condyle (rounded articular projection) 4. ramus (armlike bar)
bone markings: depressions and openings 1. meatus (canal-like passageway) 2. sinus (cavity within a bone) 3. fossa (shallow depression) 4. groove (furrow) 5. fissure (narrow, slitlike opening) 6. foramen (opening/hole through bone)
ossification -aka osteogenesis -bone tissue formation
ossification stages 1. bone formation (begins in 2nd month) 2. postnatal bone growth (until early adulthood) 3. bone remodeling/repair (lifelong)
2 types of ossification 1. intramembranous 2. endochondral
intramembranous ossification -membrane bone develops from fibrous membrane -forms flat bones (e.g. - clavicles and cranial bones)
endochondral ossification -cartilage (endochondral) bone forms by replacing hyaline cartilage -forms most of skeleton
intramembranous ossification step 1 1. ossification centers appear in the fibrous connective tissue (made up of mesenchymal cells & osteoblasts)
intramembranous ossification step 2 2. bone matrix (osteoid) is secreted within the fibrous membrane and calcifies (osteoblasts secrete osteoid, calcifies in few days)
intramembranous ossification step 3 3. woven bone & periosteum form (accumulating osteoid results in network of trabeculae called woven bone)(condensed mesenchyme forms periosteum)
intramembranous ossification step 4 4. lamellar bone replaces woven bone, just deep to periosteum. red marrow appears (trabeculae thicken, replaced with lamellar bone, forms compact bone plates)(spongy bone vascular tissue becomes red marrow)
postnatal bone growth -2nd stage of ossification -2 types of growth (interstitial/appositonal)
postnatal bone growth: interstitial vs. appositional 1. interstitial growth (increase in length of long bones) 2. appositional growth (increase in thickness and remodeling of all bones by osteoblasts & -clasts)
bone remodeling controlled by? 1. hormonal mechanisms that maintain calcium homeostasis in blood 2. mechanical/gravitational forces
calcium necessary for? 1. transmission of nerve impulses 2. muscle contraction 3. blood coagulation 4. secretion by glands and nerve cells 5. cell division
hormonal control of blood Ca2+ -primarly controlled by PTH 1. decrease in blood Ca2+ 2. parathyroid gland release PTH 3. PTH stimulates osteoclasts to degrade bone matrix and release Ca2+ into blood 4. increase in blood Ca2+
Stage 1 in healing a bone fracture 1. Hematoma forms -torn blood vessels hemorrhage -hematoma (clot) forms -site becomes swollen, painful, inflamed
Stage 2 in healing a bone fracture 2. Fibrocartilaginous callus forms -phagocytic cells clear debris -osteoblasts form spongy (1 week) -fibroblasts secrete collagen fibers to connect bone ends -mass of repair tissue now called fibrocartilaginous callus
Stage 3 in healing a bone fracture 3. bony callus formation -new trabeculae form bony, hard callus -formation continues until firm (~2 months)
Stage 4 in healing a bone fracture 4. bone remodeling occurs -in response to mechanical stressors (several months) -final structure resembles original -healed fracture complete
functional classification of joints -based on amount of movement by joint -3 classifications 1. synarthroses (immovable) 2. amphiarthroses (slightly movable) 3. diarthroses (freely movable)
structural classification of joints -based on material binding bones together and presence of joint cavity -3 structural classifications 1. fibrous 2. cartilaginous 3. synovial
fibrous joints -structural classification -bones joined by dense fibrous connective tissue -NO JOINT CAVITY -Most synarthrotic (immovable)
fibrous joint types 1. sutures 2. syndesmoses 3. gomphoses
Sutures & example -fibrous joint -rigid, interlocking joints containing short connective tissue fibers -allow for growth in youth -frontal suture of skull
Syndesmoses & example -fibrous joint -bones connected by ligaments -immovable to slightly movable -synarthrotic distal tibiofibular joint
gomphoses & example -fibrous joint -peg-in-socket joints of teeth -periodontal ligament holds tooth
cartilaginous joints -bones united by cartilage -NO JOINT CAVITY
types of cartilaginous joints 1. synchondroses 2. symphyses
synchondroses & example -cartilaginous joint -bar of hyaline cartilage unites the bones -ALL SYNATHROTIC -joint bt 1st rib & sternum
symphyses & example -cartilaginous joint -hyaline cartilage covers articulating surfaces & fused to fibrocartilage pad -strong, flexible amphiarthroses -pubic symphysis
synovial joints: general -ALL are diarthotic -includes all limb joints -MOST joints of the body
synovial joints: movements 1. gliding 2. angular movements 3. rotation
synovial joints: gliding -one flat bone glides over another
Created by: rolandowallace
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