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Oral Antibiotics
Pharm 1152
| Question | Answer |
|---|---|
| Normal bodily defenses against microorganisms | Intact skin, ciliated respiratory mucosa, physiologic response, phagocytic cells |
| Gram positive cells- stain color and cell walls | stain purple, very thich cell wall (peptidoglycan) and outer capsule |
| Gram Negative cells-stain color,cells walls | stain red, cell wall is more complex, small outer capsule and cell wall, 2 cell membrane |
| Which gram is more difficult to treat? | Gram Negative (due to complexity of composition) |
| Colonization | presence of bacteria without overt signs of infection; does not require antibiotics |
| Community Associated Infection | Acquired by someone who has not beein or treated by a healthcare facility recently |
| Health Care Associated Infection | Acquired while receiving treatment for another condition |
| Why is health-care associated infection more difficult to treat? | due to exposure to strong antibiotics in the past |
| What is the most common HDR pathogen? | MRSA |
| What is the most commonly contracted health-care associated infection? | UTI |
| Empiric Antibiotics | Antibiotic chosen that best kills the organism thought to be the most common cause of the infection |
| Definitive Antibiotic | Cultures obtained prior to antibiotics, then antibiotic therapy is adjusted based on sensitivity reports (best narrow spectrum,least toxic) |
| Prophylactic Antibiotic | Antibiotic given 30mins prior to the start of surgery or procedure |
| Subtherapeutic | When signs and symptoms do not improve |