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Chapter 15 B

biology 121

QuestionAnswer
What is the central dogma? DNA->transcription->RNA->translation->Protein
What is a start codon? the first codon of an mRNA transcript translated by a ribosome. The start codon always codes for methionine in eukaryotes and a modified Met (fMet) in prokaryotes. The most common start codon is AUG.
What is a stop codon? a nucleotide triplet within messenger RNA that signals a termination of translation. Most common:UAG
What is a reading frame? way of dividing the sequence of nucleotides in a nucleic acid (DNA or RNA) molecule into a set of consecutive, non-overlapping triplets
What are frameshift mutations? a genetic mutation caused by indels (insertions or deletions) of a number of nucleotides
What is the difference between a template strand and a coding strand? the template strand (or noncoding strand), is used as a template for RNA synthesis;
What is a Messenger RNA? is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression
What is the use of a promoter in the initiation of transcription? a regulatory region of DNA usually located upstream of a gene, providing a control point for regulated gene transcription
What are transcription factors? is a protein that binds to specific DNA sequences, thereby controlling the flow (or transcription) of genetic information from DNA to mRNA
Describe the terminator sequence. a section of genetic sequence that marks the end of gene or operon on genomic DNA for transcription.
What is a spliceosome? a complex of snRNA and protein subunits that removes introns from a transcribed pre-mRNA (hnRNA) segment. This process is generally referred to as splicing.
Contrast introns and exons. intron:nucleotide sequence within a gene that is removed by RNA splicing while the final mature RNA product of a gene is being generated.exon:sequence encoded by a gene that remains present
Name the 3 types of RNA. messengerRNA, transferRNA, ribosomalRNA
What is the function of transferRNA? small RNA chain of about 80 nucleotides that transfers a specific amino acid to a growing polypeptide chain at the ribosomal site of protein synthesis during translation
What is the function of ribosomalRNA? ribosomal RNA and protein combine to form a nucleoprotein called a ribosome. The ribosome binds mRNA and carries out protein synthesis
Created by: kapoole
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