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GRCC AD 175 III meds

Test 3 meds

QuestionAnswer
Procrit, EPO (erythopoietin) and Arnesp Colony stimulating factor meds that stimulate erythrocyte production.
Celexa, Lexapro, Prozac, Paxil, Zoloft SSRI selective seratonin reuptake inhibitors.
Decrease appetite = decreased nutrition with this type of antidepressant SSRI's: celexa, lexapro, prozac, paxil, zoloft
Why is prozac (fluoretine) not suitable option for the elderly? d/t the effects of weight loss
Which SSRI benefits elderly to increase appetite, wt gain Remeron (mirtazapine)
Side effects of remeron sleepiness, increased appetite, wt gain.
What nursing consideration ahould you consider when giving remeron Give at HS r/t sleepiness
The action of this drug reuptakes serotonin and norepinephrine Effexor
Effexor increased b/p, GI upset & constipation, along with somnolence (sleepiness) are side effects of which anti-depressant?
This drug affects sleep due to Increase frequency and urgency diuretics
This drug causes vivid dreams and insomnia parkinson meds (levadopa/carbadopa & sinemet)
This drug acts like a stimulant, tremors, anxiety and effects sleep Bronchodilators
This causes vivid dreams and extreme drowsiness or insomnia Beta Blockers
A beverage that acts as a stimulate and diuretic causes sleeplisness caffeine
This beverage causes pt to awaken earlier, unable to fall back asleep and causes nightmares alcohol.
What type of drug causes sleepliness or insomnia. antidepressants.
Ambien, Sonata, Lunesta, Rozerem Sedative/hypnotics, benzo-benzo-like meds
This sedative hypnotic is the first choice of drug to help with insomnia Ambien
How much ambien do you give at night? 5mg or 1-2mg 5mg
why is ambien the 1st drug of choice? Less hang-over effect
What is the onset of ambien? 5min, 30min, 1 hour 30 minutes
What are the side effects of ambien anxiety and agitation
Which sleeping medication has a rapid onset, and short duration. Sonata
What time can you give sonata? As late as 3am
5mg What dose do you give of Sonata? 1to2, 5mg?
What is the dosage amount can an elderly person recieve of the sleeping med Lunesta? 1 to 2mg, 5mg, 10mg? 1 to 2 mg and 1 to 2 doses per elderly
What is the duration of lunesta? Effects last about 8 hours
When should you take Lunesta? Early in evening, d/t the drug interaction.
This affects melatonin Rozerem (ramelteon) a little different class drug from the sleeping meds
Rozerem (Ramelteon) This sleep aid is not a controlled substance and there is no risk for dependence.
Why is benadryl a bad drug for the elderly? Can cause delirium, constipation, urinary retention.
This is an anticholingeric OTC drug that shoudl not be used by elderly. benadryl
What does anticholinergic effects have on the body? Dry mouth, urinary retention, blurred vision, constipation.
Pamelor (nortriptyline) Trazadone and remeron Sedative antidepressants given to someone who is having trouble sleeping at night.
What are the benefits of nortriptyline, trazadone and remeron decreases sleep latency, helps with depression and insomnia.
These sedative antidepressants cause orthostatic hypotension and daytime grogginess nortriptyline, trazadone, remeron
Melatonin natural hormone that affects the sleep/wake cycle.
levels of this natural hormone decreases in the elderly, therefore can be given as a sedative to help with sleep melatonin.
Valerian Root herbal med that decreases sleep latency and takes 1 to 3 weeks to take effect
MRS.K help with periodic limb movement disorder (nocturnal myoclonus) mirapex, requip, sinemet, klonopin treat
Mrs. N helps with restless leg syndrome mirapex, requip, sinemet,neurontin
Alpha Blockers that end in "-osin" that help in managing BPH Cadura (doxazosin) Hyrin (terazosin) Flomax (Tamsulosin) Urotraxal (alfuzosin)
The action of Alpha Blockers is to? relax spinchter, relax smooth muscle to help effectiveness of prostate.
Which of the alpha blockers, block alpha receptors in prostate only? Flomax (tamsulosin) Uroxatral (alfuzosin)
What are the side effects of alfa blockers ("-osin")? Decreases B/P, HA, fatigue, orthostasis/fainting, nasal congestion.
Should you check VS before giving alpha blockers? Yes, it is recommended you check VS because it decreases B/P, and csn cause orthostatic hypotension and fainting.
Androgen HORMONE inhibitors that end in "-asteride" shrinks prostate so pressure is not on sphincter Proscar (finasteride) Avodart (dutasteride)
Proscar (finasteride) Avodart (dutasteride) Shrinks prostate so pressure isn't on sphincter.
These BPH medications effect libido, can cause ED, and impotence? Proscar (finasteride) Avodart (dutasteride)
How long does it take Proscar and avodart to work? One month
Which BPH med circultates in blood for at lease six months, there fore should not donate blood. Proscar (finasteride) Avodart (dutasteride)
What handling precautions should everyone consider, especially pregnant women,before handling proscar and avodart? Should wear gloves since it absorbs through the skin.
This is a complimentary natural supplement to BPH medications Saw Palmetto
Saw Palmetto actions Decreases prostate size and relieves urinary symptoms, however mechanism of action is not known at this time.
B&O Suppositories Controlled substance that help with Bladder spasms
This is given following a TURP surgery to eleviate discomfort and pain from bladder spasms B&O suppositories.
A person is told that he has stage I prostate cancer. This is found unexpectedly via PSA or DRE, person has few symptoms and cancer is confined within the prostate.
These hormone medications are given following a prostectomy Lupron (leuprolide acetate) Zoladex (goserelin)
This hormone therapy works on the pituatary to decrease luteinizing hormone, thus DECREASES testosterone production Lupron and Zoladex actions
Men who are on a hormone therapy (Lupron or Zoladex) that decreases/removes testosterone may experience these type of side effects Decreased libido, impotence, hot flashes (r/t removal of testosterone = estrogen effects), osteoporosis,
How is lupron administered? Subq daily or IM qmonth or q3months. If taking subq daily, then patient is taught how to do them selves at home
Other medications that a man may recieve after prostectomy Eulexin (flutamide) Casodex (Bicalutimide) (think "-timide")
What is the action of Eulexin (flutamide) and casodex (bicalutamide)? Testorne is still there, it can bind because this med inhibits androgen uptake at the target tissues by blocking at the receptors to testosterone.
Which drugs blocks testosterone from binding to the receptor sites- (testoterone is still there, it just can't bind) Eulexin (flutamide) Casodex (bicalutamide) Teste
As a nurse, what side effects would you warn the patient if taking either Eulexin or casodex? Diarrhea, N&V,
This type of chemo therapy for breast cancer blocks the estrogen from binding to the tumor Hormone receptors Tamoxifen (Nolvadex) or Raloxifene (Evista
Tamoxifen (Nolvadex) Raloxifene (Evista) Doesn't cure breast cancer, it decreases tumor growth.
Tamoxifen (nolvadex) and Raloxifene (Evista) are hormone receptor blockers that deprive breast tumors of which hormone? Estrogen.
Who is given tamoxifen or raloxifene (Evista) used by pre and post-menopausal women
Nursing teaching for women taking tamoxifen and raloxifene Side effects; Hotflashes, N&V, weight gain, vaginal dryness, irregular periods
It is okay to smoke if taking tamoxifen (nolvadex) or Raloxifene (Evista) No, it is recommended not to smoke r/t increase risk of DVT
What action should a female take when on either tamoxifen (nolvadex) or raloxifene (Evista) and they have been having abnormal bleeding. They need to report abnormal bleeding to their doctor.
letrozole (Femara) and anastrozole (arimidex) These medications Inhibits aromatase enzyme inhibitors- deprive breast cancer of estrogen
This is a chemo drug that deprives breast cancer of estrogen by inhibiting armatase enzyme inhibitors Letrozole (Femara) Anastrozole (Arimidex)
Side effects of letrozole (femara) an anastrozole (arimidex) Hot flashes, n&v, weight gain, bloating, difficulty eating, urinary frequency and urgency
How long do side effect last when taking letrozole (femara) & anastrozole (arimidex) Side effects occur almost daily for greater than a few weeks.
Herceptin (Transtuzumab) Bio therapy medication given to treat breast cancer.
The action of Herceptin (transtuzumab) binds to HER2 nuegene and stops growth
This is a cytoxic drug that kills cancer Herceptin (trastuzumab)
Will Herceptin (Transtuzumab) help with any type of breast cancer? No, it only works if tumor has HER2 positive tumors
When is Herceptin (Transtuzumab) given It is used for women who failed other tx, and is also used in combo with other drugs.
Weekly treatment for Herceptin (Trastuzumab) IV infusion or large doses every 3 weeks.
side effects of Herceptin (Trastuzumab) Causes cardiac damage, flu-like symptoms: FEver, chills, pain, N&V
How long do the side effects of Herceptin last (Flu like symptoms and cardiac damage) They will diminish with subsequent transfusions.
Gardisil Vaccine Girls 9 to 26 years and most effective if given before exposure to HPC
Procrit, EPO and aranesp stimulates erythocyte production
Which labs should be monitored when taking pocrit, EPO and aranesp Hgb and Hct
Uses for procrit, EPO and aranesp anemia of chronic renal failure, HIV, chemotherapy and cancer.
When does therapeutic level take effect for procrit, EPO, and aranesp Therapeutic in one month.
Neumega (Opreluekin) Stimulates platelet production
How is Nuemega administered? IV
What to monitor if on Nuemega? Platelets.
Side effects of nuemega fluid retention, tachycardia, and headache
Neupogen/filgastrim Neutrophils given inpatient
Neulasta/Pegfilgastim Neutrophils given 24 hours after chemo is done as one-time long lasting injection.
what meds stimulate neutrophil production? Neupogen/filgastim Neulasta/Pegfilgrastim
Deficiency in neutrophils Neutropenia
ANC Determines risk of infection by looking at number of neutrophils.
Normal ANC > 1500
Moderate risk ANC <1000
Severe risk of ANC < 500
What does anc <500 mean extremley low count of neutrophil....severe risk...and only symptom is fever of 100.5
What is sign of infection for neutropenic patient? Fever of 100.5 or more.
what do you treat/prevent thrush for cancer patient Rinse with HCO3 or NS or H20
what mouthwash do you give someone who has stomitis Peridex, collins soln, tetra-myco-ben and artificial saliva
Anti-emiotic meds (n&V) Drugs ending in "-setron", Zofran, kytril, anzemet and aloxi
Side effects of anit-emetic meds: zofran, kytril, anzemet, aloxi ("-setron") HA, Sedation, dizziness
Med known as substance P (neurokinin)1 receptor antagonist : aprepitant (Emend) give in combo with 5HT3 blocker and dexamethasone.
Name the medication given for sever N&V Aprepitant (Emend)
Side effects of Aprepitant (Emend) Dehydration, dizziness, fatigue
Antiemetics that end in "-zine" works in the chemoreceptor zone in brain.
Prochloperazine (Compazine) & Promethazine (phenegran) Antiemetics
Side Effects of Prochloperazine (Compazine) & promethazine (phenegran) Sedation, tremors, dyskinesias, pseudoparkinsonism, decreased BP
Cyclophosphomide (Cytoxan) is an Alkylating agents
Side effects of Cyclophosphomide (Cytoxan) hemorrhagic cystitis & neutropenia.
Side effect of Cytoxan is hemorrhagic cystitis which is? Infection/irritation causing bleeding
How to treat hemorrhagic cystitis (which is side effect of taking cytoxan) Increase fluid intake before during and after chemo and give mesna
What is Mesna? It protects bladder wall and given for hemorrhagic cystitis (s.e. of taking cytoxan)
What do you assess when giving pt cytoxan? Monitor ANC because they are at risk for neutropenia (decreased neutrophils)
Platinol (cisplatin) is classifed as an Alkalyting agent
What are the side effects of taking platinol (cisplatin)? Neutropenia and nephrotoxicity.
What do you monitor when giving platinol (Cisplatin)? Monitor ANC (Neutraphil count) and GFR (Renal function)
Oxalplatin (eloxatin) side effects Neurotoxicity & exposure to cold is painful.
What do you monitor for Eloxatin (oxalplatin)? Numbness, tingling, paresthesias (r/t side effects of taking this med neurotoxicity)
Nursing care or teaching for someone taking Eloxatin (Oxalplatin) Advise to dress warmly, keep dry, avoid ice and ice water because exposure to cold is painful
Paraplatin (carboplatin) side effects Neutropenia
What do you assess when taking paraplatin? ANC...d/t risks of neutropenia
Methotrexate side effects Stomatitis (Oral ulcers), Neutropenia, Leucovorin rescue
Leucovorin rescue Given day later after high dose of methotrexate to protect cells from futher damage
At risk for fatality Leucovorin rescue is given a day after high dose of methotrexate, must be given specific time and specific length of time...can be fatal if time and dose not correct.
What do you monitor when giving methotrexate? Assess for infection: fever and ANC d/t risk of becoming neutropenic
Teaching for someone who takes methotrexate? Thorough oral assessment, treatment for stomitis, swish and spit, soft toothbrush
Cytarabine (Ara-C)side effects tumor lysis syndrome, neurotoxicity and neutropenia
Tumor lysis syndrome Side effect of taking Cytarabine (Ara-C) in which toxic substances and waste products end up in blood stream....this medication causes cells to die too fast and lead to kidney failure.
what drug would you give if Tumor lysis syndrome develops (Side effect of taking cytarabine (Ara-C)) Allopurinol (zloprim) is given prophylactically (gout med...uric acid)
What do you monitor when giving cytarabine (Ara-C)? (neutropenia) ANC, Fever, and (neurotoxicity) numbness, tingling and confusion.
5-Fluroacil (5-FU) side effects Stomatitis, Diarrhea, and thrombocytopenia
What do you monitor when giving 5-fluroacil (5-fu) Oral ulcers, oral care, eval hydration d/t diarrhea and platelet count & bleeding (r/t thrombocytopenia)
Doxorubicin (Adriamycin) side effects Cardiac toxicity and neutropenia
What test needs to be given before administering doxorubicin (Adriamycin)? MUGA scan - tests cadiac function ejaculation fraction d/t risks of cardiac toxicity.
Belomycin (Blenoxane) side effects Pulmonary toxicity and Anaphylaxis
What would you monitor or test prior to administration of Belomycin (Blenoxane)? PFT (pulomary function test) for base line and intraderma test (skin test) before each dose.
Pulmonary toxicity side effect of Bleomycin (Belnoxane) - will see pulmonary fibrosis and pneumonitis later down the road
Vincristine (Oncovin) side effect Neurotoxicity and constipation.
Paclitaxal (Taxol) side effects Neutropenia and neurotoxicity
Estrogen targeted meds Tamoxifen (nolvadex)/Raloxifene (Evista) Letrozole (Femara)/ Anastrozole (Arimidex)
Side effects of Tamoxifen and raloxifene, letrozole and arimedex? Hot flashes, n&v, wt gain, vag dryness, irregular periods, risk of DVT if smoker.
Testosterone targeted meds Eulexin, casodex, lupron and zoladex
Rituxin (rituximab) MoAbs med that is given for non-hodgkins lymphoma, targets the CD20 protein
Herceptin (trastuzumab) MoAbs med given for breast cancer, tarkets the HER2 protein.
Mylotarg (Gemtuzumab ozogamicin) MoABS med given for AML, targets Cd33 protein, not used commonly.
MoAbs antibody medication that targets one specific cell
Side effects of Herceptin, Rituxin and Mylotarg Fever, chills, rigors (tremors) diaphoresis, malaise, urticaria (hives) and N&V
Serious side effect of Herceptin, Rituxin and Mylotarg Hypoxia, hypotension, Hypertension, dyspnea
What medication shoudl be given before administering MoABS? Steroids and benadryl to help decrease reactions
Interferon Protects cells that have not been infected yet, slows tumor growth, stimulates natural killer cell suppresses oncogenes
Interferon uses Hep C, melanoma, Karposi's sarcoma, and Hairy cell leukemia
Interferon Side Effects HA, Mylagia (muscle pain), Athralgia (joint pain), Malaise, Fatigue, anorexia, wt loss, rigors (shaking)
When giving interferon, what med should be given to decrease side effects? Tylenol
Interleukin Stimulates T cell to destroy cancer, helps recognize immune cells and destroys abnormal cells.
Interleukin side effects Fatigue, GI, Skin, CNS side effects, chills, fever, rigors, capillary leadk syndrome
Capillary lead syndrome potential fatal side effect from taking interleukin.
Release of protein out of vascular system: fluid follows protein, body becomes edamatous leading to respiratory failure. Capillary leak syndrome
A lot of toxicity and given in patien where ICU is available. Interleukin
Angiogensis inhibitors Stop nutrients taht supply tumor growth, stops cells from growing
Angiogenisis inhibitor side effects Can affect good tissue growth and could lead to complications such as delayed wound healing.
Created by: Wends1984