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synovial fluid
| Question | Answer |
|---|---|
| Synovial fluid is formed as an ultrafiltrate of plasma across the ___________ | synovial membrane |
| The synoviocytes secrete _________into the synovial fluid. | hyaluronic acid |
| The large hyaluronate molecules contribute the noticeable _______ to the synovial fluid. | viscosity |
| What is called collectively that pain and stiffness in the joints caused by the damage to the articular membranes? | arthritis |
| Lab results of cynovial fluid analysis can be used to determine the pathologic origin of ________ | arthritis |
| List 4 groups of synovial disorders | noninflammatory, inflammatory, septic, hemorrhagic |
| what disease is caused by noniflammatory synovial disorder? | osteoarthritis |
| what disease is caused by inflammatory synovial disorder? | immunologic disorders(rheumatoid arthritis, lupus erythmatosus), crystal-induced gout and pseudogout |
| what kind of pathologic significance is caused by septic synovial disorder? | microbial infection |
| what kind of pathologic significance is caused by hemorrhagic synovial disorder? | traumatic injury, tumors |
| If you find milky color in synovial fluid, what do you expect? | the presence of crystals |
| What kind of test is used to measure the viscosity of synovial fluid? | mucin clot test(Rope test) |
| what is LE cell? | neutrophil with phagocytised WBC nuclei ("round body"). Found in Lupus |
| what is ragocyte? | neutrophils with dark cytoplasmic granules containing immune complexes. Found in Rheumatoid arthritis, immunologic inflammation |
| what is birefringenece? | the ability to refract light in two directions |
| What are the crystals seen in synovial fluid which are found in cases of gout? | monosodium urate |
| what are the crystals seen in cases of pseudogout? | calcium pyrophosphate |
| if you find needle shape, negative birefringence crystals in synovial fluid, what are they? | monosodium urate |
| if you find phombic square, rods, positive birefringence crystals in synovial fluid, what are they? | calcium pyrophosphate |