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Chapter 28- Sex

Reproductive System for A&P II

QuestionAnswer
Reproductive system functions in gamete production, storage, nourishment, and transport
Fertilization fusion of male and female gametes to form a zygote
Reproductive systems include gonads (testes, ovaries), ducts, accessory glands & organs, and external genitalia
Males Testes produce spermatozoa which is expelled from the body in semen during ejaculation
Females Ovaries produce oocytes (immature ovum) which travels along uterine tube toward uterus
Sex hormones androgens (males) and estrogens and progesterone (females)
Sex hormones play roles in - the development and function of the reproductive system - sexual behavior and drives - the growth and development of many other organs and tissues
System of ducts transport and store sperm, assist in their maturation, and convey them to the exterior (epididymus, ductus deferens, ejaculatory ducts, and urethra)
Accessory sex glands add secretions to semen (seminal vesicles, prostate, and bulbourethral glands)
Supporting structures scrotum (supports testes) and penis (delivers sperm into female reproductive tract)
General pathway of sperm epididymus, ductus deferens, ejaculatory duct
Accessory organs of the male reproductive system seminal vesicles, prostate gland, bulbourethral glands, scrotal sac, and penis
Scrotum - supporting structure for testes - located outside of the body - regulates temperature of the testes
Scrotum structure - raphe (external median ridge) - scrotum septum (Internally divides scrotum into two sacs, each with a single testis)
Testes - paired oval glands in the scrotum - develop near kidney and descent through inguinal canals near 7th month of fetal development
Testes structure - tunica vaginalis partially covers testes - tunica albuginea is internal to tunica vaginalis and extends inward forming septa that divide testis into lobules - each of 200-300 lobules contain 1-3 seminiferous tubules
Spermatogenic cells sperm-forming cells
Sertoli cells (sustenacular cells) support cells
Leydig (interstitial) cells secrete testosterone and are found in spaces between seminiferous tubules
Sperm production occurs in the seminiferous tubules
Spermatogenesis the sequence of events that produces sperm in the seminiferous tubules of the testes
The three processes of spermatogenesis mitosis, meiosis, and spermiogenesis
Spermiogenesis the final stage of spermatogenesis, which sees the maturation of spermatids into mature, motile spermatozoa
Spermatogonia - outermost cells in contact with the epithelial basal lamina - stem cells - replicate to retain a new stem cell and a dividing cell
Meiosis I - DNA replication and crossing over - Tetrad formation – homologous chromosome pairs line up at metaphase plate - Chromosome pairs separate - Form secondary spermatocytes (haploid – n)
Meiosis II - Single chromosomes line up at metaphase plate - Chromatids separate - Form four haploid spermatids
Spermatozoa (Sperm)- Head - nucleus with 23 chromosomes - acrosome (vesicle filled with oocyte penetrating enzymes)
Spermatozoa (Sperm)- Tail * Neck – contains centrioles forming microtubules that comprise remainder of tail * Middle piece – contains mitochondria * Principal piece – longest portion of tail * End piece – terminal, tapering portion of tail
Survival of sperm once ejaculated Sperm do not survive more than 48 hours in female reproductive tract
Gonadotropin-releasing hormone stimulates gonadotropins in the anterior pituitary to increase their secretion of the two gonadotropins, luteinizing hormone and follicle-stimulating hormone
Luteinizing hormone stimulates Leydig cells to secrete testosterone
Follicle-stimulating hormone acts indirectly on spermatogenesis
Testosterone stimulates male pattern of development of reproductive system ducts and descent of testes
Dihydrotestosterone stimulates development of external genitalia
Ducts of testis - Pressure generated by fluid secreted by Sertoli cells pushes fluid and sperm along lumen of seminiferous tubules - Fluid and sperm then enter straight tubules, rete testis, efferent ducts in epididymis and then ductus epididymis
Epididymus - consists of tightly coiled ductus epididymus - continues as ductus (vas) deferens
Ductus (vas) deferens - conveys sperm during sexual arousal through peristaltic contractions - can also store sperm several months
Spermatic cord - ascends out of the scrotum - consists of ductus deferens as it ascends through scrotum, testicular artery, veins that drain testes and carry testosterone, autonomic nerves, lymphatic vessels, and cremaster muscle
Ejaculatory ducts - formed by union of duct from seminal vesicle and ampulla of ductus deferens - terminate in prostatic urethra - eject sperm and seminal vesicle secretions just before release of semen into urethra
Urethra - shared terminal duct of reproductive and urinary systems - subdivided into prostatic urethra, membranous urethra, and spongy (penile) urethra - ends at external urethral orifice
Seminal vesicles - contribute about 60% of semen volume - secrete alkaline, viscous fluid containing fructose, prostaglandins, and clotting proteins
Prostate - contribute about 25% of semen volume - secretes milky, slightly acidic fluid containing citric acid, several proteolytic enzymes, acid phosphatase, seminal plasmin (antibiotic)
Bulbourethral glands - secrete alkaline fluid that protects passing sperm by neutralizing acids from urine in urethra - mucus lubricates end of penis and lining of urethra
Composition of Semen - Mixture of sperm and seminal fluid - Typical volume 2.5-5 mL with 50-150 million sperm/mL - Slightly alkaline pH of 7.2-7.7 due to seminal vesicle secretions
Semen - Provides transport medium, nutrients, and protection - Coagulates after ejaculation due to clotting proteins
Penis - passageway for ejaculation of semen and excretion of urine - male copulatory organ
Structure of Penis * dorsal masses- corpora cavernosa penis * ventral masses- corpus spongiosum penis * erectile tissue- skin and subcutaneous layer around masses * glans penis- terminal opening is external urethral orifice
Erection - enlargement and stiffening of penis upon sexual arousal - parasympathetic stimulation results in blood vessel dilation - vessels fill with blood resulting erection
Ejaculation - powerful release of semen from urethra to the exterior - sympathetic refles (urinary smooth muscle prevents urine from entering urethra & prevents semen from entering bladder)
Emission the discharge of a small volume of semen before ejaculation
Ovaries - paired glands homologous to the testes - produce gametes and hormones (progesterone, estrogens, inhibin, and relaxin)
Ligaments that hold ovaries in place broad ligament, ovarian ligament, and suspensory ligament
Broad ligament - a fold of the parietal peritoneum - attaches to the ovaries by a double-layered fold of peritoneum called mesovarium
Ovarian ligament anchors the ovaries to the uterus
Suspensory ligament attaches ovaries to pelvic wall
Germinal epithelium covers surface of ovary
Tunica albuginea a whitish capsule of dense irregular connective tissue located immediately deep to the germinal epithelium
Ovarian cortex consists of ovarian follicles surrounded by dense irregular connective tissue that contains collagen fibers and fibroblast-like cells called stromal cells
Ovarian medulla contains blood vessels, lymphatic vessels, and nerves
Ovarian follicles in cortex and consist of oocytes in various stages of development
Mature (graafian) follicle large, fluid-filled follicle ready to expel secondary oocyte during ovulation
Corpus luteum - remnants of mature follicle after ovulation - produces progesterone, estrogens, relaxin, and inhibin until it degenerates into corpus albicans
Oogenesis the formation of gametes in the ovaries
Uterine (Fallopian) Tubes/ Oviducts - provide a route for sperm to reach an ovum - transport secondary oocytes and fertilized ova from ovaries to uterus
Structure of Fallopian Tubes * infundibulum- the funnel-shaped portion of each tube that ends in finger-like fimbriae * ampulla- widest longest portion, making up about the lateral two-thirds of its length * isthmus- joins the uterus
Histology of the Fallopian Tubes * mucosa- ciliary conveyor belt; consist of peg cells that provide nutrition to ovum * muscularis- peristaltic contractions * serosa- outer layer
Anatomy of the Uterus - fundus, body, isthmus, and cervix - ligaments maintain position- broad, uterosacral, cardinal, and round
Layers of the Uterus * perimetrium- outer layer that is part of the visceral peritoneum * myometrium- three layers of smooth muscle * endometrium- inner lauer that is highly vascularized
Stratum functionalis lines endometrium cavity and sloughs off during menstruation
Stratum basalis permanent and gives rise to a new stratum functionalis after each menstruation
Blood supply to the uterus uterine arteries, arcuate arteries, and radial arteries
Cervical mucus produced by secretory cells of cervix mucosa
Vagina - fibromuscular canal extending from exterior of body to uterine cervix - functions as the female copulatory organ, birth canal, and exit for menstrual flow
Histology of the vagina * mucosa- continuous with uterine mucosa * muscularis- 2 layers of smooth muscle * adventitia- anchors vagina to adjacent organs
Hymen forms border around and partially closes vaginal orifice
Mons pubis cushions pubic symphysis
Labia majora homologous to scrotum
Labia minora homologous to spongy (penile) urethra
Clitoris - 2 small erectile bones and numerous nerves and blood vessels - homologous to glans penis
Vestibule region between labia minora
Bulb of the vestibule elongates masses of erectile tissue on either side of vaginal orifice
Perineum - diamond-shaped area medial to thighs and buttocks of male and females - contains external genitalia and anus
Breast hemispheric projection of variable size anterior to the pectoralis major and serratus anterior muscles and attached to them by a layer of fascia composed of dense irregular connective tissue
Lactiferous ducts a series of closely spaced openings of ducts in the nipples
Areola pigmented area of skin surrounding the nipple
Mammary gland modified sudoriferous (apocrine) gland that produces milk
Ovarian cycle series of events in ovaries that occur during and after maturation of oocyte
Menstrual cycle concurrent series of changes in uterine endometrium preparing it for arrival of fertilized ovum
Steps in the ovarian cycle - formation of primary, secondary, and tertiary follicles - ovulation - formation and degeneration of the corpus luteum - degradation of the corpus luteum
Uterine cycle - repeating series of changes in the endometrium Estrogens
Estrogens - secreted by ovarian follicles - promote development and maintenance of female reproductive structures and secondary sex characteristics - increase protein anabolism including building strong bones - lower blood cholesterol
Progesterone - secreted mainly by corpus luteum - works with estrogens to prepare and maintain endometrium for implantation and mammary glands for milk production
Relaxin - produced by corpus luteum - relaxed uterus by inhibiting contraction of myometrium - at end of pregnancy, increases flexibility of pubic symphysis and dilates uterine cervix
Inhibin - secreted by granulosa cells of growing follicles and by corpus luteum
Female Reproductive Tract * duration- ranges from 24-35 days (assume 28) * phases- menstrual, preovulatory, ovulation, postovulatory, premenstrual
Arousal leads to erection of the penis in males and clitoral erection in females
Emission and ejaculation results in semen being pushed toward external urethral opening
Detumescence - subsidence of erection - mediated by the sympathetic nervous system
Menopause the time that ovulation and menstruation cease (typically around 45-55 years old) - Decline in circulating estrogen and progesterone - Ride in GnRH, FSH, and LH
Male Climacteric - levels of circulating testosterone begin to decline - FSH and LH levels rise - gradual reduction in sexual activity
Created by: ariellebtan
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