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biotech exam 3

exam 3

QuestionAnswer
how many transplants (exclude kidney) have been available to patients on the donor list for the last 10 years? 2000-3000
how many patients were on the transplant list in the us during the month of october 2011 100000-200000
transplantation of a kidney between identical twins is an example of a isograft
the required refferral system for organ donation states that the local organ procurement organization determines whether an organ/tissue is appropriate for donation in each case
list the four categories of rejection reactions that are possible post-transplantation hyperacute acute chronic graft vs. host
As demonstrated in the classic rejection experiment, the transfer of splenic T cells from a previously grafted mouse (graft from strain A mouse into strain B mouse) to a strain B mouse will induce an accelerated rejection response against transplantation of a graft from a strain A mouse
which rejection of a transplant is based primarily upon antibody recognition (of donated tissue) by the recipient hyperacute rejection
acute rejection reactions differ from chronic rejection reactions in that antigen presenting cells are not required for direct killing of transplanted cells
passenger lymphocytes transferred during a bone marrow transplant can induce a rejection called graft vs. host
immunosuppressant drugs are primarily used to suppress_____rejection reactions chronic
transplanted xenogeneic tissue..... includes the transfer of either cells, tissues or organs from one species to another
The two are the most common species for xenograft 1. cow 2. pig
the most critical step for survival of transplanted tissue in a face transplant is... attachment of underlying vasculature
The number/ratio of adults currently living with one or more types of CV disease is 1 in 3
Atherosclerosis... includes the formation of both atheromas and calcified plaques
The main difference between soft and hard atherosclerotic plaques is calcium is a significant component of hard but not soft plaques
what percentage of PCI is performed using stents 70%
5. Restenosis of coronary arteries is both a mechanical and biological process. Please name the mechanical process and the biological process involved. mechanical: elastic recoil biologic: neointimal hyperplasia
OPCAB (off - pump coronary artery bypass)... is a suitable procedure for bypassing up to 4 arteries
traditional CABG is preffered over MIDCAB because more coronary artery vessels can be repaired at one time with the CABG procedure
surgeons performing the MIDCAB procedure can bypass 1-2 vessels
replacement vessels used during coronary bypass procedures include all of the following except ... allogeneic saphenous vein
cardiac valve failure that results in backflow of blood is called regurgitation
the cardiac valve that is most often surgically replaced the aortic semilunar valve
the type of replacement valve most often associated with calcification post-surgery is the porcine tissue aortic valve replacement
choose the statement that is false tissue valves are usually used for patients older than 65??? not sure about this one
Mechanical heart values .. require patients to take anti-coagulants
trans-apical implantation of a prosthetic aortic valve is usually recommended for stunted tissue valves. true or false true
cadaveric cardiac valve implantation... requires no immunosuppression
an LVAD differs from a TAH in that an LVAD can be used as a bridge to repair
a second generation LVAD differs from a first in its mechanism for maintaining blood flow
implant-related infections that appear months post-operatively are usually associated with surgical contamination are called deep late infections
The most frequent complication that patients experience following implantation of their VADs is... neurological complications
The kidneys excrete approximately______L of water/day 1.8
Insulin is often used to measure ______in order to assess kidney function glomerular filtration rate
Patients first become symptomatic of kidney failure when their clearence levels fall below _____% 10%
Please NAME the two options available for vascular acess when preparing for hemodialysis AV fistula artificial vascular graft
excess water is removed during dialysis as a result of ultrafiltration
patient blood pressure, immediately following dialysis session, decreases prmarily because of... the removal of water
The pathology underlying most hip and knee replacements is cartilage degeneration
A patient is diagnosed with a damaged anterior cruciate ligament. The most likely course of treatment is.... arthroscopy
The projected assesment of primary and revision TJR procedures in the US by the year 2030 states that revisions and primary procedures will increase as compared to 2011
an 18-year-old suffering with Rheumatoid Arthritis and progressive articular degeneration has been advised to have a hip replacement. This patient will most likely receive... A CoCr implant with a porous trabecular coating
A mechanism of early failure of an artificial hip replacement is dislocation
one drawback of the HMWPE (polymer) acetabular shell is... generation of wear debris over time
The largest joint in the body is the____ Knee
The largest weight bearing joint in the body is the_____ hip
All of the following are true in regards to surface-mounted prosthetics except... fibrous tissue formation at prosthetic/limb interface
Osseointegrated prosthetics... are common devices used in dental replacement surgery
all of the following are true in regards to the iLimb except has been modified to function on osseointegrated prosthetic
All of the following are true in regards to myoelectric devices except they are operated by switches located on the residual stump
What percentage of amputees in the US have upper limb amputations 10%
In the US, the primary cause for amputation is complications from Diabetes
prevention of disease by administration of material from healing pustules either by inhalation or via small cuts in the skin is called variolation
antibody responses induced by vaccination against specific pathogens are generated by T helper cells and B cells
The FluMist Influenza vaccine is a live attenuated vaccine
immunity of an individual to a specific disease that is based upon the vaccination of ana resulant protection by a group of closely associated individuals is called herd immunity
the sabin polio vaccine had potential to actively infect patients that received it due to the fact that it was a live attenuated virus (t or f) ture
administration of a purified component(s) of a pathogen that is (are) known to be immunogenic is an example of subunit vaccine
vaccines that can be used to treat a chronic, pre-existing disease are called theraputic vaccine
Created by: bjss2003b
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