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Microbiology Chpt 17
Instructor Claudia Sellers
| Question | Answer |
|---|---|
| What is innate resistance? | Defenses against any pathogen. Like a psychopath they like to kill. |
| What is adaptive resistance? | induced resistance to a specific pathogen. Cellular memory. Adaptive will pair with innate by marking the ones they want innate to kill. |
| Differentiate between humoral and cell-mediated immunity | Humoral immunity kills extra cellular pathogens (outside)is brought about through antibiotics B-cells and cell-mediated is natural and kills intracellular pathogen through exposure and the bodies T-cell. |
| Explain the function of antibodies and describe the structural characteristics. | variable regions, constant region (class of antibody) |
| IgG funtion | Monomer & found in blood, lymph,intestine. Function:enhances phagocytosis, neutralizes toxins & viruses, and protects fetus & new born. |
| IgM function | Pentamer & found in blood, lymph, B-cell surface as a monomer. Function:effective against microoganisms & agglutinating antigens, first antibodies produced in response to intial infection. |
| IgA funtion | J chain & found in secretions, blood, lymph. Function:localized protection on mucosal surface. |
| IgD function | Monomer & found in B-cell surface, blood, lymph. Function:presence on B-cell functions in intiation of immune response. |
| IgE function | Monomer & found bound to mast & basophill cells throughout body, blood. Function:allergic reactions: possibly lysis of parasitic worms. |
| Explain how an antibody aids in pathogen removal. | Obstinization, Neutralize, Agglutenate |
| name the function of B cells | Convert to plasma & B memory cell |
| Name a function of the Th cell. | Activates cell related to cell-mediated immunity: macrophages Tc cells & natural killer cells. Stimulates production of eosinophils, IgM & IgE. |
| Name a function of the Tc cell. | Cytotoxic T Lymphocyte(CTL). Destroys target cells on contact; generated fro T cytotoxic(Tc) cell. |
| Name a function of the Ts cell. | Stop response |
| Name a function of the APC. | Antigen-Presenting Cells. Digest antigen, Ag fragments on APC surface w/MHC (B-cells, dendritic cells, & Activated macrophages) |
| Name a function of the MHC | |
| Name a function of the activated macrophage | |
| Where are class 1 and class 2 MHCs located? | Notes |
| How do Th1 and Th2 cells differ? | Interact with? |
| Define apoptosis and five a potential medical application. | Maybe use in tumor cells |
| Describe clonal selection theory. | Dormat until activated |
| Identify at least one function for cell mediated immunity. | |
| Identify at least one function for cytokines. | |
| Identify at least one function for interleukins. | |
| Identify at least one function for interferons. | |
| Distinguish a primary from seconday immune response. | Shouldn't get sick from same thing twice. |
| Clonal selection | development of clones of B and T cells against a specific antigen. |
| Clonal deletion | elimination of B and T cells that react w/self. |
| Naturally acquired active immunity | Resulting from infection |
| Naturally acquried passive immunity | Transplacental or via colostrum |
| Artificiall acquired active immunity | Injection of Ag (vaccination) |
| Artificially acquired passive immunity | Injection of Ab (eg:snake bite venom) |
Created by:
Shellzzz
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