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cytochromes

QuestionAnswer
Alcool (chronique) Induit CYP2E1
Alcool (non chronique) Inhibe CYP2E1
Analgésiques (codéine) Substrat CYP2D6, CYP3A4
Anesthésiques Substrat CYP2E1
Antiarrhytmiques Substrat CYP3A4
Antibiotiques Substrat CYP3A4
Antidépresseurs Substrat CYP1A2, CYP2C9, CYP2C19, CYP2D6, CYP3A4
Antiépileptiques Substrat CYP3A4
Anti-inflammatoires non stéroïdiens Substrat CYP2C9
Antimalariens Substrat CYP3A4
Antinéoplasiques Substrat CYP3A4
Antiparkinsoniens Substrat CYP3A4
Antipsychotiques Substrat CYP1A2, CYP2D6, CYP3A4
Antirejets Substrat CYP3A4
Antiviraux Substrat CYP3A4
Benzo (sauf Lorazépam, oxazépam, témazépam) Substrat CYP3A4
Bloqueurs de AT2 Substrat CYP2C9
Bloqueurs des canaux calciques Substrat CYP3A4
Bupropion Inhibe CYP2D6
Cimétidine Inhibe CYP2D6
Ciprofloxacine Inhibe CYP1A2, CYP3A4
Clarithromycine Inhibe CYP3A4
CYP1A2 : Affinité? Faible affinité/forte capacité
CYP2C9 : Affinité? Forte affinité/faible capacité
CYP2D6 : Affinité? Forte affinité/faible capacité
CYP3A4 : Affinité? Faible affinité/forte capacité
Diabète non contrôlé Induit CYP2E1
Diltiazem Inhibe CYP3A4
Disulfiram Inhibe CYP2E1
Érythromycine Inhibe CYP3A4
Fluconazole Inhibe CYP2C9
Fluoxétine Inhibe CYP2D6
Fluvoxamine Inhibe CYP1A2, CYP2C9, CYP2C19
Hypoglycémiants oraux Substrat CYP2C9
Indinavir Inhibe CYP3A4
Inhibiteurs de la HMG-CoA Substrat CYP3A4
Inhibiteurs de la transcriptase inverse Substrat CYP3A4
IPP Substrat CYP2C19
Isoniazide (première dose) Inhibe CYP2E1
Isoniazide (prise régulière) Induit CYP2E1
Itraconazole Inhibe CYP3A4
Kétoconazole Inhibe CYP3A4
Macrolides Substrat CYP3A4
Mexilétine Inhibe CYP1A2
Néfazodone Inhibe CYP3A4
Norfluoxétine Inhibe CYP2D6, CYP3A4
Obésité Induit CYP2E1
Paroxétine Inhibe CYP2D6
Propafénone Inhibe CYP1A2
Quinidine Inhibe CYP2D6
Ritonavir Inhibe CYP2C9, CYP2D6, CYP3A4
Rx cardiovasculaires Substrat CYP2D6
Stéroïdes (cortisone) Substrat CYP3A4
Sulfaphénazole Inhibe CYP2C9
Tabagisme Induit CYP2E1
Thiazolidiediones (Glitazones) Substrat CYP2C8
Ticlopidine Inhibe CYP2C19
Triptans Substrat CYP3A4
Created by: matduke
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