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Pro-Inflammatory Cytokines

Interleukin-1 (IL-1) actions? Induces fever, stimulates production of prostaglandins, increases growth of CD4+ T cells
Interleukin-2 (IL-2) actions? Increases growth and differentiation of T-lymphocytes, enhances NK cell activity against cancer cells
Interleukin-6 actions? Stimulates liver to produce fibrinogen and protein C, increases rate of bone marrow production of stem cells, increases numbers of sensitized B-lymphocytes
Tumor necrosis factor (TNF) Induces fever, major cytokine involved in rheumatoid arthritis damage, increases leukocyte adhesion, participates in graft rejection, induces cachexia and muscle breakdown, incuces cell death, stimulates delayed hypersensitivity reactions and allergy
Created by: 1526511508