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Step 1 10.24.12
Microbiology IX
| Question | Answer |
|---|---|
| What happens with the chances of non Hodgkin's lymphoma in CD$ count in HIV? | lower CD4 = higher NHL |
| What would histoplasma capsulatum cause in an AIDS Pt? | low grade fevers, cough, hepatosplenomegaly, tongue ulcer |
| What labs might be seen with histoplasma capusulatum in an ADIS pt? What CD4 level | oval yeasts within macrophages, CD<100 |
| What might candida albicans cause in an AIDS pt? | fluffy white cottage cheese lesions (thrush) |
| What labs migth be seen in a C. albincans in an AIDS pt? What CD4 level? | pseudohyphae, commonly oral if CD4<400, esophageal if CD4<100 |
| What sx might be caused by an infection of bartonella henselae in an AIDS pt? | bacillary angiomatosis. superficial vascular proliferation with neutrophilica inflammation |
| What might be seen in an AIDS pt infected with JC virus? What CD4 level? | PML. encephalopathy due to demyelination. CD <200 |
| What sx and labs might be seen in an AIDS pt with cryptosporidium? CD4 level? | acid fast cysts in stool. CD4 <200. chronic, watery diarrhea |
| What Sx and labs might be seen in an AIDS pt with toxoplasma gondii? CD4 level? | neurologic absesses, many ring enhancing lesions . CD4<100 |
| What Sx and labs are seen in an AIDS pt infected with cryptococcus neoforman? CD4 level? | meningitis (maybe encephalitis), india ink stain reveals narrow based budding and large capsule. CD4<50 |
| What mgiht be seen in an AIDS pt infected with CMV? CD4 level? | retinitis. cotton wool spots on fundoscopic exam. maybe esophagitis. Also interstital pneumonia with owls eyes nucelar inclusions.CD4<50 |
| What might be seen in a AIDS Pt infected with HHV-8? | Kaposi's sarcoma, lymphocytic inflammation, neoplastic proliferation of vasculature |
| What might be seen in an AIDS Pt infected with EBV? | hairy leukoplakia often on lateral tongue. associated with NHL. Waldeyers ring on oropharynx |
| What might bee seen in an AIDS pt infected with HPV? | squamos cell carcinoma (MSM) or cervix |
| What infection might cause a primary CNS lymphoma with focal or multiple lesions in AIDS pt? | EBV |
| What might aspergillus fumigatus in AIDS pt? | plueritis pain, hemoptysis, infiltrates on imaging |
| What might be seen in an AIDs pt infected with pneumocystis jirovecii? CD4 level? | pneumonia esp CD4<200 |
| What might be seen in an AIDS pt infected with mycobacterium avium and intracellulare? | Tb like disease, esp with CD4<50 |
| What is the mechanism of prion disease? | conversion of nornam protein to prion protein to a Beta pleated sheet which is transmissible. get spongiform encephalopath, demetia, ataxia death. |
| What is an example of a sporadic prion disease? | Crutzfeld Jakob- rapidly progressive dementai |
| What is an example of an inherited prion disease? | Gertsmann Straussler scheinker syndrome |
| What is an example of an acquired prion disease? | kuru |
| What is the normal dominant flora of the skin? | staph epidermidis |
| What is the normal dominant and colonizer flora of the nose? | S epidermidis, colinized by S aureus |
| What is the dominant normal flora of the oro pharynx? | viridans strep |
| What is the dominant normal flora of dental plaque? | strep mutans |
| What is the dominant normal flora of the coloon? | Bacterioides fragillis > E. coli |
| What are the dominant and colizing flora of the vagina? | Lactobacillus, colinized by E. coli, group B step |
| Do neonates delivered by cesarian have flora? | not at first but are rapidly colonized |
| What does vibrio parahemolyticus cause? | food poisioning from seafood |
| What does Vibrio vulnificus cuase? | seafood poisoning, wound infections from water or shellfish |
| What causes food poisoning from reheated rice? | bacillus cerues |
| What causes food poisoning in meats, mayonaise, custard with a preformed toxin? | S. aureus |
| Where might CLostridium pefringens cause food poisoing? | reheated meats |
| What might cause food posiing in a bulging can? | C. botulinum |
| In what setting might E. coli 0157 : H7 cause food posioning? | undercooked meat |
| What setting might salmonella cause food poisoning? | pultry meat eghgs |
| What can be said about the onset and offset of foodposioning wiht S. aureus and B. cereus? | starts quick, ends quick |
| What 3 bugs might mimic appendicitis? | Yersinia enterocolitica, C. jejuni, non typhoidal salmonella. mesenteric adenitis |
| What might cause a bloody diarrhea with comma or S shaped organisms grown at 42C? | Campylobacter |
| What organism might cause a bloody diarrhea with lactose negative, flegellar motility? | Salmonella |
| What organism might cause bloody diarrhea, lactose negative, low ID, making Shiga toxin? | Shigella |
| What organism might cause bloody diarrhea, HUS, making shiga like toxin? | enterohemorrhagic E. coli 0157 H7 |
| What organism might cause bloody diarrhea and invade the colonic mucosa? | enteroinvasive E. coli |
| What organism might cause bloody diarrhea outbreaks in a day care an pseudoappendicitis? | yersinia enterocolitica |
| What organism might cause a bloody diarrhea with protozoa? | entamoeba histolytica |
| What oragnism might cause a watery diarrhea, travelers diarrhea, with ST LT toxins? | enterotoxigenic E. coli |
| What organism might cause a watery diarrhea with comma shaped organisms and rice water diarhea? | vibrio cholerae |
| What organism might cause a watery diarrhea with pseudomembranous colitis? | C. difficle |
| What might cause a watery diarrhea or gas gangrene? | C. perfringens |
| What protozoa might cause a watery diarrhea especially in the ICPt? | Giradia, cryptosporidium |
| What viruses might cause a watery diarrhea? | rotavirus, adenovirus, norwalk virus |
| What is the most common cause of neonatal pneumonia <4weeks? | Group B strep, E coli |
| What is the most common cause of pneumonia in children 4w to 18 y/o? | RSV, Mycoplasma, Chlamydia (young kids), Streptococcus pneumonidiae |
| What are the most common causes of pneumonia in adults? 18-40 | Mycoplasma, C. pneumonia, S pneumoniae |
| What are the most common causes of pneumonia in adults? 40-65? | S. pneumonidae, H influnzae, Anaerobes, virsues, Mycoplasma |
| What are the most common causes of pneumonia in the elderly? | S. pneumonidae, Influenza, Anaerobes, H influenzae, G- rods |
| What 2 bacteria are especially nosocomial pneumonia? | Staphylococcus, enteric G- rods |
| What bacteria cause pneumonia by aspiration? | anaerobes |
| What bacteria cause pneumonia especially in alcoholic or IVDA? | Staphylococcus, klebsiella, S. pneumonidae |
| What bacteria is especially known to cause pneumonia in CF? | pseudomonas |
| What bacteria are especially known to cause pneumonia post viral? | staphylococcus, H. influenzae |
| What pathogens cause atypical pneumonia? | mycoplasma, legionella, chlamydia |
Created by:
tjs2123
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