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Lecture 3
Introduction to Membranes
| Question | Answer |
|---|---|
| Integrins | Receptor protein that interconnects the extracellular matrix and cytoskeleton |
| Phagocytosis | Type of endocytosis in which large particles are taken up by cell |
| Exocytosis | Cellular secretion of biological molecules by fusion of vesicles |
| Endocytosis | Cellular uptake of molecules via a formation of vesicles from membrane |
| Fluid Mosaic Model | Accepted model of cell membrane, mosaic of proteins integrated within fluid bilayer of phospholipids |
| Intergral Membrane Protein | Has hydrophobic and hydrophilic regions that extend to the corresponding sides in the bilayer |
| Peripheral Membrane Protein | Loosely bound to surface of membrane/integral protein. Not imbedded in lipid bilayer |
| Amphiphilic Molecule | Molecule with both hydrophobic and hydrophilic characteristics |
| Hypotonic | Solution surrounds the inside of a cell, causing an uptake of water |
| Hypertonic | Solution surrounds outside of cell, causing the cell to lose water |
| Isotonic | Solution surrounding the cell causes no movement |
| Plasmolysis | Walls of cell shrivel up due to loss of water within a cell (hypertonic environment) |
| Turgid | Swollen, when cell takes up water (hypotonic environment) |
| Flaccid | Limp, when water leaves cell (hypertonic environment) |
| Active Transport | Movement of substance against concentration gradient. Monitored by transport proteins and requiring energy |
| Passive Transport | Diffusion of substances across membrane, not requiring energy |
| Electrogenic Pump | Active transport protein that generates voltage across membrane while pumping ions |
| Proton Pump | Active transport protein, uses ATP to transport H+ out of the cell against gradient |
| Cotransport | Coupling "downhill with uphill" |
| Cholesterol | Acts as a pylon when bilayer experiences high temperatures, increases fluidity when bilayer is in low temperatures |
| Selective Permeability | Property of membranes that allows them to regulate the passage of substances across |
| Membrane Potential | Difference in electrical charge across plasma membrane due to different distribution of ions. |