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Eye Disorders

Pharmacology

QuestionAnswer
FDA Cosmetics Safety Guidelines Keep eye cosmetics clean Don't swap Keep containers clean Wash hands before applying Ingredients must be declared Discard mascara after 3 months of purchase False eyelashes and adhesives are cosmetics and must be labeled appropriately.
Blepharitis Inflammation of lash follicles at eyelid margin. Can be caused by bacteria, meibomian gland dysfunction or seborrhea. Blinking may cause granular sensation. Loss or inversion of eyelid may occur.
Treatment of blepharitis Warm compress; eyelid hygiene; antibiotics (top or sys); top anti-inflammatory agent. Don't use contacts during acute phase. NP only treat bacterial.
Antibiotic Ointments Blepharitis Erythromycin 0.5% opthalmic ointment Bacitracin 500 units/gram ointment Opthalmic fluorquinolone ($$$): gatifloxacin, levofloxacin, moxifloxacin
Patient education Blepharitis Good eyelid hygiene Warm massages Tends to be chronic in nature
Conjunctivitis Injected blood vessels in the periphery of the eye-along the conjunctival sac especially inner/outer canthus; areas of inflammation upper and lower lid.
Phlytenular conjunctivitis Gray/yellow nodules on cornea or conjunctiva; persist several days-1 week. Associated allergic reaction to staph or systemic TB. Ulcerate but heal w/out scar. Recommended tx: corticosteroid or ABX. Refer to opthamologist
Chlamydial Conjunctivits (Trachoma) Requires systemic therapy f/b monthly tx of abx oinmt. Eyelid edema*, photophobia*, and lacrimation. *uncommon-send to opth. Follic. phase (small foll appear in upper conj over 10d); invasion of cornea w/ neovascularization (month-year); corneal scarring.
Treatment Chlamydial Conjunctivitis Doxy 100 mg BID x 10d Azithromycin 1gm x 1 dose Pregnant women, nursing mother, infants:substitute erythromycin Developing countries w/ endemic trachoma: topical tetracycline or erythromycin top should be applied first 5d of month x 6 mo.
Corticosteroids for Conjunctivitis DO NOT PRESCRIBE corticosteroids AS AN NP. They suppress the immune system. Could lead to corneal scarring and blindness.
Treatment Allergic Conjunctivitis Topical anhistamines Topical non-steroidal (anti-inflammatory) Topical Mast-cell stabilizers Take care w/ topical decongestants. Patients can become dependent in order to clear redness in the eye. Can lead to chronic state where eyes are addicted.
Treatment adenoviral conjunctivitis Use supportive therapy: clean lids; cold compresses; lubricant to eyes; separate towels and washcloth; clean basins frequently.
Instructions for contacts Take out contacts before administering eye drops and leave out for 10 minutes after; don't use ointments (eye drops day ointments at night).
Dry Eye Artificial tears in day and lubricating ointment at night. Etiology often autoimmune in nature or r/t Bells Palsy. Cornea can be more easily abraded w/ dryness.
OPTHAMOLOGIST AND DRY EYE Pilocarpine increases tearing. Topical cyclosporine, immunosuppresive, decreases cytokine production that causes dry eye; topical corticosteroid.
Created by: jniebyls
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