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Meds
Meds for MSII
| Question | Answer |
|---|---|
| Donepezil (aricept), Rivastigmine (Exelon), Galantamine (Razadyne). | Cholinesterase inhibitors for mild-moderate DEMENTIA. Inhibits breakdown of acetycholine. |
| Memantine (Namenda) | For mild to moderate DEMENTIA. Suppresses glutamate an excitatory neurotransmitter. |
| Beta-Interferon | May change long-term prognosis of MULTIPLE SCLEROSIS. |
| Copaxone | Immunomodulator. Med for MS. |
| Novantrone | Supresses T-Cells and B-Cells in MS. |
| Dexamethason (Decadrone) | Prevents cerebral edema. Strong anti-inflammatory. Used in brain injury pts/INTRACRANIAL BLEED |
| lorazepam (Ativan), diazepam (Valium), phenytoin (Dilantin), fosphenytoin (cerebyx). | ANTISEIZURE for Status Epilepticus. |
| levetiracetam (Keppra), | ANTICONVULSANT. No need to monitor blood levels. Monitor CBC |
| phenytoin (Dilantin) | ANTICONVULSANT. Causes ginival hyperplasia, bone marrow suppression, rash, multiple drug interactions, IV vesicant. |
| carbamazipine (Tegretol) | ANTICONVULSANT. Causes bone marrow suppression. Monitor blood level and CBC. |
| divalproex (Depakote) | ANTICONVULSANT. Causes hepatotoxicity, bone marrow suppression. Monitor blood levels, CBC, and LFTs. |
| Medications to avoid Myasthenia Gravis | aminoglycosides, procainamide, beta blockers, quinindine, phenytoin, psychotropic drugs, neuromuscular blockers. |
| Tensilon | used to diagnose Myasthenia Gravis. It is short-acting acetycholinesterase blocker. |
| levodopa/carbidopa (Sinemet), | ANTIPARKINSON |
| ropinirole(Requip), pramipexole (Mirapex), rotigotine (Neupro) | ANTIPARKINSON. Dopamine Agonists. |
| benztropine (Congentin) | ANTIPARKINSON. Anticholinergic. |
| tPA | STROKE. Must be initiated 3-4.5 hours. Contraindications: Rapidly improving symptoms, bleed on CT, major sugery or trauma within 14 days, Recent arterial puncture and noncompressible site, SBP>185, Low platelets, elevated PT or PTT |
| methotrexate | Antineoplastics. RHEUMATOID ARTHRITIS |
| Plaquenil | Antimalarial. RHEUMATOID ARTHRITIS |
| Entanercept, infliximab | RHEUMATOID ARTHRITIS DMARD - TNF inhibitors. |
| pregabalin (Lyrica) | FIBROMYALGIA. |