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Pharm test 3
chap 29
| Question | Answer |
|---|---|
| Anticonvulsants | topiramate (Topamax), divalproex (Depakote) , |
| Antidepressants | fluoxetine (Prozac), amitriptyline (Elavil) |
| NSAIDs | aspirin, naproxen (Aleve), ibuprofen (Advil, Motrin) |
| Serotonin (5-HT) agonists - Adverse effects: | Category X Peripheral vasoconstriction GI, muscle cramps |
| "Triptan” agents (5-HT agonists) | treat/stop migraine |
| "Triptan” agents (5-HT agonists) adverse | Chest tightness & drowsiness |
| Fluoxetine | selective serotonin reuptake inhibitor (SSRIs): antidepressants |
| Fluxetine adverse effects | anxiety, insomnia, tremor, anorexia, sexual dysfunction |
| amitriptyline | tricyclic antidepressant (TCA) |
| anticonvulsant adverse effects: | sedation, tremor, weight gain |
| amitriptyline adverse effects | drowsiness, tremor, anticholinergic effects (dry mouth blurred vision, urinary retention |
| naproxen - NSAIDs | block thromboxane synthesis and platelet aggregation, reduce the release of serotonin |
| Timolol - B antagonist, propanolol | propanolol widely used for migraine prophylaxis but can cause more CNS side effects than timolol |
| Calcium channel blockers: | used for mygraine prophylaxis, by preventing the vasoconstrictive phase of migraine headaches |
| Ergotamine and dihydroergotamine | treatment of migraine headaches and cluster headaches |
| Classes for migraines prevention | anticonvulsants |
| Classes for migraines prevention | antidepressants |
| Classes for migraines prevention | NSAIDs |
| Classes for migraines prevention | B antagonists |
| Classes for migraines prevention | Calcium channel blockers |
| Classes for migraines prevention | 5-HT 2 receptor antagonist |
| "Triptan" for treating migrains | sumatriptan |
| "Triptan" for treating migrains | rizatriptan : oral |
| "Triptan" for treating migrains | zolmitriptan : oral |
| "triptan" adverse effects | chest tightness |
| "triptan" adverse effects | weakness |
| "triptan" adverse effects | somnolence |
| "triptan" adverse effects | dizziness |
| "triptan" adverse effects | abnormal tingling or burning sensation (paresthesias) in the skin or various parts of the body |
| "triptan" adverse effects | cause coronary vasospasm |
| "triptan" contraindicated | should not be used in pt with angina pectoris, MI, or coronary artery disease, uncontrolled hypertension |
| Other drugs prevent migrains | Vitamins.supplement.herbals |
| Naproxen | either to prevent or to abort a migraine ATTACK |
| Combination formulations of acetaminophen, butalbital, caffeine | aborting migraine headaches |
| Isometheptene | terminate migrain headaches |
| Tramadol | one of the most widely used opioid drugs for the treatment of migraines |
| Butorphanol | nasal spray formulation for rapid onset of action |
| prochlorperazine | IV, aborting UNremitting migraine headache |
| Tension HA's treatment | NSAID and muscle relaxants, amitriptyline |
| Tension ha | bilateral, nonpulsatile, band-like pressure |
| TRiptan drugs and ergot alkaloids moa | cause vasoconstriction, used with restricted dose to avoid rebound headache and adverse effects |
| ergots adverse effects | nausea, vomiting, muscle cramps |
| triptan and ergots (ergotamine, dihydroergotamine) | not for coronary artery disease pt |
Created by:
prinluu
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