Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Don't know
Know
remaining cards
Save
0:01
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards
share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Step1 10.3.12

Microbiology IV

QuestionAnswer
G- diplococci, ferments maltose. pathogen? Neisseria meningitidis
G- diplococci, does not ferment maltose. pathogen? Neisseria gonorrhoeae
G- coccoid rods requiring factors V, X. pathogen? Haemophilus influenze
G- coccoid rods from animal bites, pathogen? Pateurella
G- coccoid rods causing kennel cough? Bordeltella Pertussis
G-, oxidase +, comma shaped, grows at 42 C. pathogen? campylobacter jejuni
G-, oxidase +, comma shaped, grows in alkaline media. pathogen? vibrio cholerae
G- rods, fast lactose fermenter. What 3 pathogens? Klebsiella, E.coli, enterobacter
G- rods, slow lactose fermenter. What 2 pathogens? Citrobacter, Serratia
g- rods, non lactose fermenter, oxidase -, 3 pathogens? Shigella, Salmonella, Proteus
G- rods, lactose non fermenter, oxidase +. pathogen? Pseudomonas
Pink colonies on McConkey's agar is a sign of? What 5 pathogens? lactose fermentation(enteric bacteria). macConKEE'S agar: Citrobacter, Klebsiella, E. coli, enterobacter, Serratia
What lactose fermenting bacteria produces Beta- galactosidase and what does it do? E. coli. breaks down lactose into glucose and galactose
What type of resistance do G- organisms have to penicillin? resist penicillin G, but can be vulnerable to some derivatives like ampicillin. G- outer layer prevents entry of penG and vacnomycin
Which ferments maltose and glucose and which only glucose, Neisseria meningitidis and Neisseria gonorhoeae? Meningococcus= Maltose and glucose. Gonococci=just glucose. Both have an IgA protease
What is the difference between capsules of meningococus and gonococcus? Gonococus has no polysaccardie capusle, meningococcus does
Which has a vaccine meningococcus or gonococcus? `menigococcus has a vaccine (not type B)
What diesease does neisseria meningitidis caused? Meningococcus causes meningococcemia, and meningitis. can get Waterhouse-Friedrichesen syndrome
What diseases does Neisseria gonorhoeae cause? gonnorhea, septic artritis, neonatal conjunctivitis, PID, Fitz-Hugh-curtis Syndrome
How do you treat gonococcus? ceftriaxone
How do you prophylax for meningococcus? rifamin to close contacts
How do you treat Nesseria meningitidis? ceftriaxone or peniccillin G
What dieseas does Haemophilus Infleunza cause? epiglottitis in children "cherry red", meningitis, otitis media, pneumonia
What type of H. influenzae causes invasive disease and how? capsular type b most invasive disease. have an IgA protease
What 2 ways can H. influenzae be grown? chocolate agar: it needs factor V(NAD+) and X(hematin). can also be grown with S. aureus which provides factor V.
How do you treat H. influenzae meningitis and what is given for prophylaxis? treat: ceftriaxone Propylaxis: rifampin
What is the composition of the H. influenzae vaccine and when is it given? type B capsular poly saccardie conjugated to diptheria toxin. given b/w 2-18 motnhs
What is Legionnaire disease and Pathogen? severe pneumonia+fever.caused by Legionella pneumophila
What is Pontiac fever, pathogen? mild flulike caused by legionella pneumophila
How is Legionella grown and how is it stained and detectedclinically? stained with silver. grows on charcoal yeast extract culture with iron and cysteine. Detect with urine ag. (legionairre:silver helmet, around charcoal campfire, iron dagger-is no sissy-cysteine)
How do you get Legionnaires disease or pontiac fever? both from legionella from water source. no person to person transmiossion
How do you treat legionarries disease or pontiac fever? Legionella pneumophila. treat with eryhtromycin
Who gets pseudomonas? wound and burn infections
What Sx does Pseudomonas cause? PSEUDO: Pneumonia (esp CF), sepsis (black lesions). external otitis, UTI, drug use and Diabetic osteomyelitis. also hot tub folliculitis
What is a major danger of pseudomonas infection in DM? malignant otitis externa
Aerobic g- rod, non lactose, Oxidase+, pyocyanin (blue green pigment), grapelike smell. Pathogen and source? pseudomonas aeurginosa. from water source
What are the toxins of Pseudomonas aeruginosa? endotoxin (fever shock), and exotoxin A(inactivates EF-2)
How do you treat Pseudomonas aeruginosa? aminoglycosolide + extended spectrum penicillin
What are the major virulence factors common to all E.coli and what do they cause? fimbriae( cystitis and pyelonephritis), K capsule (pneumonia and neonatal meningitits, LPS endotoxin (septic shock
What is the toxin, mechanism and disease of EIEC? invades internal mucosa causing necrosis and inflammation. no toxin. Invasive dysentery with picture like shigella
What is the toxin, mechanism and disease of ETEC? has a labile/stable toxin. no inflammation or invasion. cuases Travelers diarrhea
What is the toxin, mechanism, and disease of EPEC? no toxin, adheres to apical surface flatten villi preventing absorbiton. diarhhea in Pediatrics
What is the mechanism and toxin of EHEC? Shiga like toxin and hemolytic-uremic syndrome (anemia, thrombocytopenia, acute renal failure). cuases sweeling of endothelium causing hemolysis and reduced renal blood flow. endothelium damage consume platlets
What is the triad of hemolytic uremic syndrome and what pathogen? anemia, thrombocytopenia, acute renal failure. seen in EHEC
how do you distinguish EHEC from other E. coli and what disease does it cause? causes dysentary. distinguish it because it won't ferment sorbitol
How do you remember the diseases of EIEC, ETEC, EPEC, EHEC? second letter: I=invasive dysentary T= travelers diarrhea P: pediatric diarrhea H: hemolytic uremic syndrome
What is the normal role of klebsiella and whom does it cause problems? intestinal flora which can cause lobar pneumonia in alcoholic, diabetics when aspirated
What sputum is seen in Klebsiella and what setting besides pneumonia can klebsiella cause? currant jelly sputum. can cause nosocomial UTIs
What are the 4 A's of Klebsiella? Aspiration pneumonia, Absess in lung or liver, Alcoholics, diAbetics
How do you differentiate between Shigella and Salmonella? both cause bloody diarrhea. Salmonella have flagell and can disseminate hematogenously, have animal reservoir and make H2S. Shigella: more virulent move via actin rockets no flagella
What is the effect of abtx on shigella vs salmonella? abtx can prolong sx of salmonella but shorten sx of shigella
Which is more virulent, shigella or salmonella? shigella
What diseases do Campylobacter jejuni cause and how is it transmitted? bloody diarrhea, esp in children. fecal oral transmission thru food, meat, unpasteurized milk.
What can be a long term consequence of infection with G- comma shaped, oxidase postiive, grow at 42 C bacteria? Campylobacter jejuni. can commonly precede Guillain-Barre syndrome
What diseases does Vibrio cholerae cause and how? toxin permanantly activates Gs, increases cAMP. profuse rice water diarrhea. need rehydration
What dieseases goes Yersinia enterocolitica cause and how do you get it and what serious problem can it mimic? trnsmitted by pet feces, milk or pork. Outbreaks of diarrhea among faycares. Get MESENTERIC ADENITIS which can mimic Crohns or apendicitis
What bacterium causes 90% of gastric ulcers? .Helicobacter pylori
What else is H. pylori a risk factor for besides peptic ulcers? gastic adenocarcinoma, lymphoma
G- rod, urease +, creates alkaline environment. Pathogen? H. pylori
What is the therapy for H. pylori infection? detected with urease breath test. Triple therapy: proton pump inhibitor, clarithromycin, amoxicillin or metronidazole
What are 3 spirochete families? Borellia, Leptospira, Treptonema. borelia is biggest!
How do you visulaize Borellia? aniline dyes(Wright's or Giemsa stain)
How do you visualize treptonema? dark field microscopy
Question mark shaped bacteria found in water contaminated by animal urine, pathogen? Leptospira interrogans
What diseases does Leptospira interrogans cause? Leptospirosis- flu like sx, jaundice, photophobia, conjunctivitis: surfers in tropics. Weil's disease: ictohemorragic leptospirosis
What is Weil's disease and etiologic agent? Leptospira interrogans. icterohemmoragic leptospirrosis. sever jaundice, azotemia, from liver and kidney dysfunction, fever hemorrgae anemia
What causes Lyme disease? Borelia burgdorferi, transmitted by Ixodes tick(also vector for Babesia)
What are the Sx of Lyme disease and where is it most commonly seen? erythema chronicum migrans: bulls eye red rash with central clearing. also affects CNS, heart
How do you differentiate between Shigella and Salmonella? both cause bloody diarrhea. Salmonella have flagell and can disseminate hematogenously, have animal reservoir and make H2S. Shigella: more virulent move via actin rockets no flagella
What is the effect of abtx on shigella vs salmonella? abtx can prolong sx of salmonella but shorten sx of shigella
Which is more virulent, shigella or salmonella? shigella
What diseases do Campylobacter jejuni cause and how is it transmitted? bloody diarrhea, esp in children. fecal oral transmission thru food, meat, unpasteurized milk.
What can be a long term consequence of infection with G- comma shaped, oxidase postiive, grow at 42 C bacteria? Campylobacter jejuni. can commonly precede Guillain-Barre syndrome
What diseases does Vibrio cholerae cause and how? toxin permanantly activates Gs, increases cAMP. profuse rice water diarrhea. need rehydration
What dieseases goes Yersinia enterocolitica cause and how do you get it and what serious problem can it mimic? trnsmitted by pet feces, milk or pork. Outbreaks of diarrhea among faycares. Get MESENTERIC ADENITIS which can mimic Crohns or apendicitis
What bacterium causes 90% of gastric ulcers? .Helicobacter pylori
What else is H. pylori a risk factor for besides peptic ulcers? gastic adenocarcinoma, lymphoma
G- rod, urease +, creates alkaline environment. Pathogen? H. pylori
What is the therapy for H. pylori infection? detected with urease breath test. Triple therapy: proton pump inhibitor, clarithromycin, amoxicillin or metronidazole
What are 3 spirochete families? Borellia, Leptospira, Treptonema. borelia is biggest!
How do you visulaize Borellia? aniline dyes(Wright's or Giemsa stain)
How do you visualize treptonema? dark field microscopy
Question mark shaped bacteria found in water contaminated by animal urine, pathogen? Leptospira interrogans
What diseases does Leptospira interrogans cause? Leptospirosis- flu like sx, jaundice, photophobia, conjunctivitis: surfers in tropics. Weil's disease: ictohemorragic leptospirosis
What is Weil's disease and etiologic agent? Leptospira interrogans. icterohemmoragic leptospirrosis. sever jaundice, azotemia, from liver and kidney dysfunction, fever hemorrgae anemia
What causes Lyme disease? Borelia burgdorferi, transmitted by Ixodes tick(also vector for Babesia)
What are the Sx of Lyme disease and where is it most commonly seen? erythema chronicum migrans: bulls eye red rash with central clearing. also affects CNS, heart, joints. Seen in NE US
What are the 3 stages of Lyme disease? Stage 1: erythema chronicum migrans, flu like Stage 2: Bell's plasy, cardiac problems (AV nodal block) Stage 3: chronic monoarthritis, migratory polyarthritis
What is a mnemonic for the Sx of Lyme's disease? BAKE a Key LYME pie: Bell'a palsy, arthritis, Kardiac blocke, Erythema migrans
How do you treat Lyme disease? doxycylcine and ceftriaxone
What is the presentation of primary syphilis? painless chancre
What is the presentation of secondary synphilis? macularpapular rash (palms and soles). condylomata lata. See treptonemes in chancres and condylomata lata
What is the presentation of tertiary syphilis? Gummas (chronic granulomas), aortititis(vasa vasorum destruction), tabes dorsailis (neurosyphilis). Argyll-robinson pupil
What are the major Signs of tertiary syphilis? broad based ataxia, positive Romberg, Charcot joint, stroke with no HTN
How do you screen for and confirm syphilis infection? Screen: VDRL Confirm: FTA-ABS
What are the sx of congenital syphilis? saber shins, saddle nose, CN VIII deafness, Hutchinson's teeth, mulberry molars
What is an Argyll-robertson pupil? With what disease is it associated constricts with accomidation but not reactive to light. tertiary syphilis. "Prostitute's pupil"
What 4 cases can cause a false positive VDRL? (VDRL)Viruses, drugs, rheumatic fever, lupus, leprosy
What does VDRL detect? detects antibody which reacts with cardiolipin
Created by: tjs2123