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Hematopoietic Drugs

Drugs recognition: chap 17

QuestionAnswer
Iron (ferrous sulfate, fumarate, gluconate) Minerals
Iron Dextran Minerals
Folic Acid Vitamins
Vitamin B12 (cyanocobalamin, hydroxocobalamin) Vitamins
epoietin-alpha (Epogen) – red blood cell stimulation
darbopoietin-alpha (Aranasp) – red blood cell stimulation
filgrastim (Neupogen) – white blood cell stimulation
pegfilgrastim (Neulasta) – white blood cell stimulation
epoietin-alpha (Epogen) Hematopoietic Growth Factors
darbopoietin-alpha (Aranasp) Hematopoietic Growth Factors
filgrastim (Neupogen) Hematopoietic Growth Factors
pegfilgrastim (Neulasta) Hematopoietic Growth Factors
What is Hematopoietic Growth Factors for? Hematopoietic deficiencies
What are the growth factors do? stimulate the differentiation and maturation of bone marrow cells
what treat anemia caused by chronic renal failure, cancer chemotherapy, and zidovudin therapy, hematologic malignancies (lymphoma)) and heart failure? epoetin and darbepoetin
ferrous sulfate, ferrous gluconate, ferrous fumarate : indications orally for iron deficiency anemia
ferrous sulfate, ferrous gluconate, ferrous fumarate: adverse GI: epigastric pain, nausea, vomiting, diarrhea, constipation, black stool, liquid will stain teeth
what will cause lethal toxicity? large quantity of iron
what is iron dextran for? routes IM and IV for iron deficiency anemia
adverse effect of iron dextran anaphylactin, IM: pain, sterile abscesses, brown discoloration of skin IV: flushing, hypotensive
what are folic acid and vit B12 for? folic acid deficiency (spina bifid), before and during pregnancy, Neural tube defects & megaloblastic anemia
What is cyancobalamin (Vitamin B12)for? lack of intrinsic factor, vitamin B12 deficiency, pernicious anemia, cyanide poisoning
epoetin-α (Epogen), darbepoetin (Aranesp) indications Chronic Renal Failure, drugs, hematologic malignancies, HF
Hemato growth factors: epoetin, darbepoetin adverse effects HTN, stroke, MI, HF, death
What is Hematopoietic Growth Factors for? Hematopoietic deficiencies
What are the growth factors do? stimulate the differentiation and maturation of bone marrow cells
what treat anemia caused by chronic renal failure, cancer chemotherapy, and zidovudin therapy, hematologic malignancies (lymphoma)) and heart failure? epoetin and darbepoetin
ferrous sulfate, ferrous gluconate, ferrous fumarate : indications orally for iron deficiency anemia
ferrous sulfate, ferrous gluconate, ferrous fumarate: adverse GI: epigastric pain, nausea, vomiting, diarrhea, constipation, black stool, liquid will stain teeth
what will cause lethal toxicity? large quantity of iron
what is iron dextran for? routes IM and IV for iron deficiency anemia
adverse effect of iron dextran anaphylactin, IM: pain, sterile abscesses, brown discoloration of skin IV: flushing, hypotensive
what are folic acid and vit B12 for? folic acid deficiency (spina bifid), before and during pregnancy, Neural tube defects & megaloblastic anemia
What is cyancobalamin (Vitamin B12)for? lack of intrinsic factor, vitamin B12 deficiency, pernicious anemia, cyanide poisoning
epoetin-α (Epogen), darbepoetin (Aranesp) indications Chronic Renal Failure, drugs, hematologic malignancies, HF
Hemato growth factors: epoetin, darbepoetin adverse effects HyperTension, stroke, MI, Heart Failure, death
filgrastim (Neupogen) sargramostim (Leukine) indications Neutropenia from chemotherapy, bone marrow transplant, leukemias
filgrastim (Neupogen) sargramostim (Leukine) adverse effects bone pain, spenomegaly
Created by: prinluu