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hyperlipidemia

Drugs recognition: chap 15

QuestionAnswer
rosuvastatin (Crestor) HMG CoA Reductase Inhibitors “Statins”
atorvastatin (Lipitor) HMG CoA Reductase Inhibitors “Statins”
simvastatin (Zocor) HMG CoA Reductase Inhibitors “Statins”
pravastatin (Pravachol) HMG CoA Reductase Inhibitors “Statins”
lovastatin (Mevacor) HMG CoA Reductase Inhibitors “Statins”
fluvastatin (Lescol) HMG CoA Reductase Inhibitors “Statins”
pitavastatin (Livalo) HMG CoA Reductase Inhibitors “Statins”
cholestyramine (Questran) Bile Acid Binding Resins
colestipol (Colestid) Bile Acid Binding Resins
colesevelam (Welchol) Bile Acid Binding Resins
ezetimibe (Zetia) Cholesterol Absorption Inhibitor
ezetimibe/simvastatin (Vytorin) Cholesterol Absorption Inhibitor
gemfibrozil (Lopid) Fibric Acid Derivatives
fenofibrate (Tricor, Antara, Lipofen, Trilipix) Fibric Acid Derivatives
niacin (Niaspan-rx, otc’s) Other Drugs
omega-3-fatty acids (ethyl ester) (Lovaza) Other Drugs
Statins indications Hypercholesterolemia & mixed hyperlipidemia
statins adverse effects GI (constipation, diarrhea, heartburn, abdominal cramps) Liver enzyme elevation & hepatitis Rhabdomyolysis
Bile Acid-binding Resins indications Hypercholesterolemia, pruritis, & diarrhea
Bile acid-binding resins adverse effects constipation, fecal impaction, and rash
niacin adverse effects gastric irrigation, glucose intolerance, myalgia, rhabdomyolysis, myopathies, vasodilation, flusing, prutitus
Fibric acid derivatives adverse effects allergic reactions, blood cell deficiencies, myalgia, rhabdomyolysis and other myopathies
rhabdomyolysis is fatal form of skeletal muscle toxicity (myopathy)
etimibide (Zetia) ezetimibide/simvastatin indications Hypercholesterolemia
cholesteron absorption inhibitors: etimibide (Zetia) ezetimibide/simvastatin adverse effects Headache Myalgia
niacin indications Mixed hyperlipidemia HDL deficiency
anticoagulant drugs indications Patients who have had HIT Unstable angina Acute MI
anticoagulant drugs adverse effects Vasodilation, pruritis (itching), & flushing Hepatitis GI Hyperglycemia
omega-3 fatty acids lower triglyceride levels, improve LDL-c to HDL-C ratio
Fibric acid derivatives gemfibrozil (Lopid) fenofibrate (Tricor) indications Hypertriglyceridemia Mixed hyperlipidemia
Fibric acid derivatives gemfibrozil (Lopid) fenofibrate (Tricor) contraindication avoid with statins
Fibric acid derivatives moa Decrease VLDL & LDL while raising HDL
drug to increase HLD niacin
niacin contraindicated with pt with diabetes
Bile Acid-binding Resins moa Binds with bile acids to prevent recycling which makes the liver produce more from the cholesterol , reduce cholesterol LDL
Created by: prinluu
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