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Patho ch3 unit quiz
Pathophysiology Online Class
| Question | Answer |
|---|---|
| What are major water compartments of body? | Intracellular fluid (ICF), Extracellular fluid (ECF) |
| What % of total body water held in each compartment? | The standard value for TBW is 60% of the body.ICF holds 40% of total body water and ECF holds 20% of total body water. |
| What force moves water between ICF and ECF? | osmosis |
| What forces moves water between the plasma and interstitial fluid? At what part does it occur? | osmosis and hydrostatic pressure across the capillary membrane |
| What is called the movement across the capillary wall? | net filtration |
| Explain the Starling law | Net filtration=(forces favoring filtration)-(forces opposing filtration) |
| How much and where do we have our total body water? | Total body water is the sum of fluid within all compartments. The standard value for TBW is 60% of the weight of a 70kg adult male.(42L) |
| Why different TBW at different ages--fetus, infant, adult, elederly? | fetus store less fat and hold less water.As age increases, a person gains fats and loses muscle, then he/her loses TBW. Also renal mechanism to regulate fluid becomes less functional as getting older, it also affects TBW. |
| Who has higher TBW, men or women? | Men has higher TBW than women because men store less fat and more muscle than women. |
| What is edema? | Edema is a problem of fluid distribution that results in accumulation of fluid within the interstitial spaces. |
| what causes edema? | The four most common mechanisms are: 1)increased capillary hydrostatic pressure, 2)decreases plasma oncotic pressure, 3)increased capillary membrane permeability, 4)lymphatic obstruction. |
| What are aquaporins? | The water channel proteins that provide permeability to water when water between ICF and ECF moves by osmotic forces. |
| What is renin-angiotensin-aldosterone system? | the system promotes and inhibits secretion of aldosterone and regulate sodium and water balance, and also lower the blood pressure, and increase water volume. |
| When renin is secreted? | when blood pressure is low and renal perfusion decreased. |
| At where renin is secreted? | juxtablomerular cells |
| what is Natriuretic peptide? | they are produced by heart and kidney. They decreases blood pressure and increases sodium and water excretion. |
| Explain tonicity. | it describes the effective osmolality of a solution. Solutions have relative degrees of tonicity. |
| What is isotonic solution. | it has the same osmolality or concentration of particles as the ICF or ECF. |
| What is hypotonic solution? | It has a lower concentration and is thus more dilute than body fluids. |
| What is hypertonic solution | it has a higher concentration. |
| what organs are involves in acid/base balance? | lung and kidney.(reapiratory systems and renal systems) |
| how buffers work? | they are substances that can absorb excessive acid or base without a significant change in pH. |
| what are buffers? | Buffers exist as acid-base pairs; the principal plasma buffers are carbonic acid-bicarbonate, protein(hemoglobin), and phosphate. |
| When ADH is secreted? | It is secreted when plasma osmolality increases or blood pressure decreases. |
| How ADH works? | It stimulates renal reabsorption of water and increase blood volume and dilute the blood. Also It stimulates blood vessels to construct and increase blood pressure. |
| What ADH generates? | Blood pressure and water volume |
| what evaluation is used to distinguish different types of metabolic acidosis? | anion gap |
| Give the formula for anion gap | (Na+ + K+)-(Cl- + HCO3-) |
| What is normal range of AG? | 10-12mEq/L |
| What if AG is over normal range, what do you call it? | Metabolic acidosis |