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Virulence factors

capsules, fimbrae, outer membrane proteins, toxins, enzymes,

QuestionAnswer
Prevent phagocytic cells form making sufficient contact capsule
Adhere to epithelial surfaces of the host by binding to receptors on the host fimbrae
causr bovine contagious pyelonepghitis Corynebacterium renale
species of bacteria that has fimbrae that attach to the renal pelvis in cows Corynebacterium renale
Virulent components of outer membrane proteins Techoic acids Protein A M-Protein
protein found in G+ bacteria outer membrane and have antiphagocytic properties Techoic acid
in Staphlococcus aureus, binds to the Fe region of IgG Protein A
antiphagocytic because it competes with Fe receptors of phagocytic cells Protein A
causes equine strangles Streptococcus equi subspecies equi
extends through the bacterium's hyaluronic acid capsule, allowing it to adhere to host surfaces M-Protein
Colonizes the female reproductive epithelium of cows, causing bovine campylobacteriosis Campylobacter fetus subspecies veneralis
colonize the GI, respiratory, and urogenital tract Mycoplasma and Ureaplasma species
a change in the production of antigenic type that allows the bacteria to avoid elimination by the host's immune system phase variation
antigens that can undergo phase variation surface fimbral flagellar
The smooth form of this bacteria is avirulent and has a somatic antigen. M. bovis
In M. bovis, the smooth form (has/lacks) a somatic antigen and (has/lacks) fimbrae, making it (virulent/avirulent) and (hemolytic/nonhemolytic) has lacks avirulent nonhemolytic
In M. bovis, the rough form (has/lacks) somatic antigens and (has/lacks) fimbrae, making it (virulent/avirulent) and (hemolytic/nonhemolytic). lacks has virulent hemolytic
In M. bovis, ___ light converts (smooth/rough) bacteria to (smooth/rough) bacteria. UV smooth rough
In the disease state of Enterobacteriacea, the bacteria is (smooth/rough) and (has/lacks) somatic antigens smooth has
In Enterobacteriacea that is in bacteriologic media, the bacteria is (smooth/rough) and (has/lacks) somatic antigens rough lacks
types of bacteria that have temperature-dependent motility Listeria monocytogenes, Yersinia enterocolitica, Y. pseudotuberculosis
bacteria with temp-dependent motility are motile at ___, with ______ flagella and nonmotile at ___ 20C peritrichous 37C
Bacteria that can invade mucous membranes Brucella, some Leptospira serovars, L. monocytogenes, some Mycobacterium species
gives LPS ist endotoxicity Lipid A moiety
manifestations of LPS endotoxin 1. stimulation of leukeocytes to release endogenous pyrogens 2. activation of the clotting system 3. induction of circulatory abnormalities
act on the hypothalmus to produce a fever pyrogens
cause leukopenia and hyperglycemia pyrogens (?)
result of increased vascular permeability caused by LPS impaired circulation, shock, or death
type of bacteria that release LPS (gram...) G-
G- bacteria release more LPS when (alive/lysed) than when (alive/lysed), causing the clinical symptoms lysed alive
Composition of endotoxins protein
prototoxins are proteolytically cleaved produce holotoxins
has 1A subunit and 1 or 5 B units holotoxin
Function of the 1A subunit of holotoxins enzymatic activity
Function of the B subunit(s) of holotoxins bind to receptors on susceptible eukaryotic cells
Types of toxins cytotoxins enterotoxins neural toxins
Toxins that inhibit protein synthesis in eukaryotic cells cytotoxins
Created by: jesters
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