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PATH-Noneoplastc Dis
NonNEOPLASTIC DISEASES OF BONE
| Question | Answer |
|---|---|
| name 4 benign fibro-osseous lesions | periapical cemento-osseus dysplasia focal cemento-osseus dysplasia florid cemento-osseuos dysplasia firbous dysplasia |
| periapical cemento-osseus dysplasia | >mandibular anteriors, pts >30yrs >women (black women) early lesion-well circumscribed, radiolucent older lesion- radiolucent, central opacifications |
| focal cemento-osseous dysplasia | isolated, well-delinated radiolucent, <1.5cm asymptomatic >women, 30-50yrs >whites posterior mandible |
| florid cemento-osseous dysplasia | disordered cementum+bone dvlpmnt multiple quads. max+man >blk women 49+yrs irreg. opacification composed of dense, sclerotic bone, cementum |
| Dx and Tx of florid cemento-osseous dysplasia | in edentulous pt sclerotic mass may perforate mucosa->osteomyelitis=surgery+antibiotics |
| fibrous dysplasia | replacement of bone w/ abnormal fibrous CT w/ calcification histo.: vascularized, celluar fibrous CT w/ irreg. trabeculae bone |
| 2 types of fibrous dysplasia | monostotic fibrous dysplasia ploy fibrous dysplasia |
| monostotic fibrous dysplasia | single one involvement max>man. kids+young adults asymptomatic, swelling/bulging of buccal plate |
| polystotic fibrous dysplasia | more than 1 bone involvment kids w/ female predilection can exhibit bowing, assoc. w/ dull aching pain cafe au lait spots |
| name 3 types of polystotic fibrous dysplasia | cranio fibrous dysplasia jaffe-lichtenstein albright syndrome |
| craniofacial fibrous dysplasia | involves max. w/ extension into sinuses+adj. zygoma, sphenoid, occipital bone |
| jaffe lichtenstain | involves multiple bones+ cafe au lait macules on skin |
| albright syndrome | endocrine abnormalities, puberty in females,stunting/deformity of skeletal growth result of premature closing of epiphyseal plates cafe au lait spots |
| how polystotic fibrous dysplasia appears radiographically and clinically? | asymptomatic "ground glass", diffused radiopacitiy unilateral enlargement |
| Dx and Tx of polystotic fibrous dysplasia | cellular fibrous CT, irreg. shaped bony trabeculae tx-surgical recontouring of bone for cosmetic reasons |
| paget disease of bone (osteitis deformans) | chronic metabolic bone disease resorption, osteoblastic repair, remineralization of involved bone men 50+yrs max>man |
| how does paget disease of bone appear clinically and radiographically? | pain, enlargement common, spaces increase b/t teeth as bone enlarges patchy radiolucent+radiopaque "cotton wool" hypercementosis loss of lamina dura, obliteration of pdl |
| Dx and Tx of Paget Disease Bone | serum alkaline phosphatase level elevated in active disease "mosaic bone" tx- experimentalm, disease slow progressive |
| central giant cell granuloma | aka. central giant cell lesion well-vascularized CT containing multinucleated giant cells occurs w/in bone chronic calcium deficiency |
| osteomalacia | chronic, calcium deficiency, vitamin D Rickets(kids) assoc. delayed tooth eruption+perio.dis. |
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