Anxiety Pharma Word Scramble
|
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Question | Answer |
Anti-anxiety med: adequate trial = | 6-8 weeks |
Classes of anti-anxiety drugs | Benzodiazepines; SSRIs; SNRIs; Buspirone; other (hydroxyzine, imipramine, and propranolol) |
Which drugs are firstline for anxiety? | Benzodiazepines; SSRIs; SNRIs |
Tx of choice for acute anxiety relief | Benzodiazepines |
Anxiety tx of choice for noncompliance / avoidance of withdrawal sx | Diazepam |
Advantage of buspirone | lack of sedation AE; good if pt h/o substance abuse |
Advantage of beta blockers in anxiety tx | good for pt w/ hx of CV sx; adjunct for refractory |
MOA: Benzodiazepines | Potentates inhibitory effect of GABA |
MOA: SSRIs | Selectively inhibit the reuptake of 5-HT by blocking the 5-HT transporter |
MOA: SNRIs | Block the reuptake of 5-HT and NE (and DA) |
MOA: Buspirone | SSRI |
MOA: Hydroxyzine | Potent antihistaminergic, anticholinergic, and antispasmodic effects |
MOA: Imipramine (TCA) | Blocks reuptake of 5-HT and NE |
MOA: propranolol | beta-blocker |
Bz side effects | CNS depression / sedation; anterograde amnesia; dependence / abuse |
Shorter acting benzodiazepines | Alprazolam; Lorazepam; Oxazepam |
Longer acting benzodiazepines | Chlordiazepoxide; clonazepam; Diazepam |
Benzodiazepines: increased toxicity / mortality if: | taken with other CNS depressants |
Benzodiazepine OD mild sx | drowsy, confusion, somnolence, impaired coordination, diminished reflexes, lethargy |
Benzodiazepine OD serious sx | ataxia, hypotonia, hypotension, hypnosis, coma, death |
Benzodiazepine OD: Tx: | gastric lavage, supportive measures, flumazenil |
Benzodiazepine Withdrawal Sx | anxiety, restlessness, insomnia, agitation, muscle tension, irritability |
Bz withdrawal sx more likely in: | users of high doses for long periods of time |
Tx: Bz withdrawal | Taper over several weeks when discontinuing |
Antidepressants for anxiety dz: | SSRIs; Venlafaxine; Mirtazipine; TCA; MAOI |
SSRI dosing for anxiety | delayed tx response; initiate w/smaller dose than AD dose |
Anxiety: MAOI reserved for: | refractory cases |
FDA approved for panic disorder | paroxetine, fluoxetine, sertraline, venlafaxine XR, alprazolam, clonazepam |
Tx for OCD | CBT firstline for mild; CBT and SSRI for severe (clomipramine if 2-3 failed SSRIs); tx mania, depression, or psychosis first |
Created by:
Abarnard
Popular Pharmacology sets