Pre-/Anesthetics Word Scramble
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Drug | Category | Action | Use | Notes |
Diazepam | Benzodiazepine | - GABA(A) Rc facilitation - | - sedative - pre-anesthetic | - safer because don't activate without GABA - reverse with flumazenil |
Opioids | - stimulate pre and post ORc | - analgesia (4-6 hrs) - sedation - antidiarrheal | ||
Fentanyl | Opioid | - Full MOR agonist | - profound pain relief - | - overdose causes seizures |
Pentazocine | Opioid | - Full KOR agonist, partial MOR agonist | - with fentanyl full analgesia but less overdose risk | |
Codeine | Local anesthetic Cocaine derivative | - Metabolized to morphine | - analgesic | |
Carfentanyl | Opioid | - chemical immomibilzation | - 10000x analgesic potency of morphine | |
Etorphine (M99) | Opioid | - 3000x morphine - wildlife tranquilizer - reversal agent naloxone (human), diprenorphine (animal) | ||
Sodium Thiopental | Barbiturate | - Inhibit BABA dissociation - increase open channel time | - Induction Agent | - low TI - intense CNS depression - can induce GABA(A)R on its own |
Propofol | Sedative/anesthetic | - binds GABA(A)R at same site as ethanol | - sedative and anesthetic - induction - short surgical prodecures | - still low TI but better than barbiturates - fast, smooth, complete recovery - most hypotensive |
Ketamine | Phencyclidine (dissociative anesthetic) | - NMDA Rc block - GABAR inhibitor | - | - Inhibits senses without unconsciousness - Mod-profound anesthesia |
Nitrous oxide (N2O) | Inhalant Anesthetic | Lowers amount of other inhalants needed Analgesic | ||
Cocaine | Local anesthetic | Sympathomimetic (lowers NE release | Topical rhinolaryngologic | |
Procaine | Local anesthetic | Ester - short duration | ||
Bupivacaine | Local anesthetic | slower onset (15 min), longer duration (2-4hr) | Ventricular arrhythmias from IV bolus | |
Levobupivicaine | Local anesthetic | Bupivacaine s-enantiomer | ||
Proparacaine | Local anesthetic | Eye anesthetic | ||
Lidocaine | Local anesthetic | |||
Halothane | Cyclopropane Inhalant Anesthetic | Anesthetic | - sensitizes myocardium to epi (arrhythmias) Hepatotoxic metabolites | |
Isofluorane | Inhalant Anesthetic | Anesthetic | Poor tissue solubility No hepatic/renal toxicity Pungent odor | |
Sevofluorane | Inhalant Anesthetic | Anesthetic |
Created by:
Annya8
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