Barbiturates Word Scramble
|
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Question | Answer |
Barbiturates generally _______ the firing of CNS neurons. | depress |
_________ are organic compounds derived from barbituric acid. | Barbiturates |
The antiseizure properties of ________ were discovered in 1912, and this drug is still commonly prescribed for seizures. | phenobarbital |
Barbiturates generally have a _____ margin of safety. | low |
Barbiturates have a _____ potential for dependence. | high |
Barbiturates cause profound ________ _________. | CNS depression |
Barbiturates intensify the effects of _______ in the brain. | GABA |
__________ is able to suppress abnormal neuronal discharges without causing sedation. | Phenobarbital |
Phenobarbital is inexpensive, long acting, and produces a _______ _______ of adverse effects. | low incidence |
When phenobarbital is given orally, it may take _______ _______ to achieve optimum effects. | several weeks |
Phenobarbital is sometimes a preferred drug for the pharmacotherapy of _______ seizures. | neonatal |
Barbiturates are effective against all major seizure types except ________ seizures. | absence |
Other than phenobarbital, _________ is occasionally used for epilepsy treatment. | mephobarbital |
Mephobarbital (Mebaral) is converted to phenobarbital in the ______ and offers no significant advantages over phenobarbital. | liver |
________ (Mysoline) has a pharmocolgic profile similar to phenobarbital. | Primidone |
Primidone is among the drugs used effectively to ________ GABA action. | potentiate |
Barbiturates were once used on a regular basis to terminate the condition of _______ _________. | status epilepticus |
Intravenous administration of __________ is the preferred treatment for status epilepticus. | diazepam |
A common adverse effect of barbiturates is ________. | somnolence |
Serious adverse effects of barbiturates include agranulocytosis, dependence, Stevens-Johnson syndrome, angioedema, ________, respiratory depression, CNS depression, coma, and death. | laryngospasm |
Luminal is the trade name of which barbiturate? | phenobarbital |
What category of controlled substance does phenobarbital belong to? | IV |
Phenobarbital is a pregnancy category ____ drug. | D |
With overdose, _______ may cause severe respiratory depression, CNS depression, coma, and death. | phenobarbital (Luminal) |
Common side effects of phenobarbital include ________, vitamin deficiencies, and laryngospasm. | drowsiness |
Severe uncontrolled pain, pre-existing CNS depression, porphyrias, severe respiratory disease with dyspnea or obstruction, and glaucoma or prostatic hypertrophy are __________ of phenobarbital. | contraindications |
Phenobarbital should not be taken with ______ or other CNS depressants. | alcohol |
Alcohol and other CNS depressants ________ barbiturate action. | potentiate |
Barbiturates taken with alcohol and other CNS depressants increase the risk of life-threatening ________ _________ or cardiac arrest. | respiratory depression |
Phenobarbital _________ the metabolism of many other drugs, ________ their effectiveness. | increases; reducing |
Barbiturates may effect ________ tests and increase serum phosphatase. | bromsulphalein |
Phenobarbital is in the pharmacologic class _________; GABAa receptor agonist. | barbiturate |
Kava and valerian may potentiate ________ while taking barbiturates. | sedation |
There is no specific _______ for barbiturate overdose. | treatment |
_________ may be effective in facilitating removal of phenobarbital from the body. | Hemodialysis |
Removal of a barbiturate drug may be accomplished by _______ _______ or use of activated charcoal. | gastric lavage |
Barbiturate overdose treatment is supportive and consists mainly of _______ _________ and mechanical ventilation. | endotracheal intubation |
Treatment of _______ and ________ may be necessary with barbiturate overdose. | bradycardia; hypotension |
Created by:
NursingStudyStack
Popular Pharmacology sets