Fusion Inhibitors Word Scramble
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Question | Answer |
Fusion/Entry inhibitors | Enfuvirtide, Maraviroc |
blocks fusion of HIV receptors to bind to CD4/chemokine receptors (CCR5/CXCR4) on host cell | Fusion/Entry Inhibitors |
fusion inhibitor, only S.C., no cross-resistance, interferes w/gp41 (HIV fusion with host cell), no drug interactions, no CYP, resistance: mutation of HIV gp41 | Enfuvirtide |
CCR5/CXCR4 | chemokine receptors necessary for entrance of HIV into CD4 cells; located on host cell |
use only CCR5, fusion inhibitor, tropism tested first, decrease immunity, | Maraviroc |
gp41/gp120 | receptors located on HIV virus |
glycoprotein gp41 inhibited by what fusion inhibitor | enfuvirtide |
Created by:
cburrows
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