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roadmap exam 5 DM

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Question
Answer
RAPID ACTING INSULINS names, onset, peak, duration, admin   Lispro(Humalog)/ Aspart(novolog)/Glulisine(apidra) O=5-15, P=1hr, D=2-4hrs admin 5-15 min before or with food  
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REGULAR-SHORT ACTING INSULINS names, onset, peak, duration, admin   HumalogR, NovolinR, Iletin IIR ALL CLEAR SOLUTIONS/ O=20-30, P=2-3hr, D=4-6hr admin 20-30min b4meals ONLY INSULIN APPROVED FOR IV USE  
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INTERMEDIATE INSULINS names, onset, peak, duration, admin   NPH / NovolinL/ NovolinN/ Lente O=2-4hrs, P=4-12hrs, D=16-20hrs CLOUDY SOLUTIONS / draw up last!! eat at onset of action 2-4hrs  
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LONG ACTING/BASAL/PEAKLESS INSULINS names, onset, peak, duration, admin   DO NOT MIX WITH OTHER INSULINS MUST ADMIN SEPARATELY once daily injection Glargine(Lantus) / Detemir(levemir) O=1hr, no peak, D=24hrs  
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insulin is secreted by the __ cells glucagon is secreted by the __ cells   insulin = pancreatic Beta cells glucagon = pancreatic Alpha cells both from islets of Langerhans  
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RAPID ACTING INSULINS names, onset, peak, duration, admin   Lispro(Humalog)/ Aspart(novolog)/Glulisine(apidra) O=5-15, P=1hr, D=2-4hrs admin 5-15 min before or with food  
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REGULAR-SHORT ACTING INSULINS names, onset, peak, duration, admin   HumalogR, NovolinR, Iletin IIR ALL CLEAR SOLUTIONS/ O=20-30, P=2-3hr, D=4-6hr admin 20-30min b4meals ONLY INSULIN APPROVED FOR IV USE  
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INTERMEDIATE INSULINS names, onset, peak, duration, admin   NPH / NovolinL/ NovolinN/ Lente O=2-4hrs, P=4-12hrs, D=16-20hrs CLOUDY SOLUTIONS / draw up last!! eat at onset of action 2-4hrs  
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LONG ACTING/BASAL/PEAKLESS INSULINS names, onset, peak, duration, admin   DO NOT MIX WITH OTHER INSULINS MUST ADMIN SEPARATELY once daily injection Glargine(Lantus) / Detemir(levemir) O=1hr, no peak, D=24hrs  
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insulin is secreted by the __ cells glucagon is secreted by the __ cells   insulin = pancreatic Beta cells glucagon = pancreatic Alpha cells both from islets of Langerhans  
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action of insulin   storage hormone, moves glucose from blood to muscles, liver, and fat cells  
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why do muscle liver and fat cells need insulin   -transport/metabolize glucose for energy -stimulate storage of glucose as glycogen in liver -signals liver to stop releasing glucose -enhances fat storage -accelerates transport of amino acids(from protein) into cells  
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when is glucagon released & what does it do   released when low glucose levels tells liver to release stored glucose  
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how does exercise lower blood glucose   increases uptake of glucose by muscles and improves insulin utilization also increases HDL, and lowers triglycerides & cholesterol  
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DM pts should avoid exercise when...   ketones in urine and glucose over 250  
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snacks and exercise for DM pts   eat a 15gm carb snack prior to exercise, if strenous, eat snack after and @ bedtime TO AVOID HYPOGLYCEMIA FS - before, during, after exercise  
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hypoglycemia   blood glucose =/<50-60 -too much insulin -too little food -excessive physical exercise  
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3 main causes of DKA   missed insulin doses illness/infection undiagnosed diabetes  
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s/s of DKA   Hyperglycemia (too little insulin)/ dehydration & electrolyte loss / acidosis / blurred vision, weakness, headache  
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evidence of ketoacidosis   serum bicarb 0-15 pH 6.8-7.3 low sodium/potassium increased BUN, creatinine, hematocrit  
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treatment of DKA   1) 0.9% sodium chloride IV (increase volume/reverse dehydration) 2) 0.45 sodium chloride IV HYPOTONIC 3)glucose =/<300 = 5%dextrose&water (D5W) 4)Regular insulin IV, slow 5U/hr WATCH ECG, AND POTASSIUM LEVELS  
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HHNS s/s   hypotension dehydration tachycardia neuro signs-hallucinations/periph tingle  
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treatment of HHNS   same as DKA watch ECG, and fluid overload  
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