Chapter 34, 35, 36, 37
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| A highly ____________ microbe is one that can produce disease when present in minute numbers. | Virulent
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| Though they are genetic ERRORS, these can result in making bacteria more resistant to drugs. | Mutations
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| When anti invectives are effective against a wide variety of microorganisms, they are classified as: | Broad Spectrum
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| This infection is one that occurs secondary to anti-infective drug therapy. | Super Infection
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| An enzyme secreted by bacteria that limits the therapeutic usefulness of penicillins is: | Penicillinase (or beta-lactamase)
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| These antibiotics are safe alternatives to penicillin because they can generally be administered over a shorter time. | Macrolides
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| These antibiotics are narrow-spectrum, treat gram negative bacteria, but have ear and kidney toxicity. | aminoglycosides
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| The pharmacologic category of amoxicillin (Amoxil, Trimox). | penicillin
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| The pharmacologic category of ciprofloxacin (Cipro). | flouroquinolone
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| The pharmacologic category of cefepime (Maxipime). | cephalosporin
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| The pharmacologic category of gentamicin (Garamycin). | aminoglycoside
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| The pharmacologic category of neomycin. | aminoglycoside
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| The pharmacologic category of erythromycin (E-Mycin, Erythrocin). | macrolide
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| The pharmacologic category of doxycycline (Vibramycin). | tetracycline
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| The pharmacologic category of cephalexin (Keflex). | cephalosporin
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| The pharmacologic category of rifampin (Rifadin, Rimactane). | antitubercular agent
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| What is a major reason for prescribing vancomycin? | MRSA
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| What are a couple major adverse effects from vancomycin? | red-man syndrome, ototxicity, nephrotoxicity
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| Why would amoxicillin be used instead of penicillin G? | penicillinase resistance
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| Which class of antibiotics would be used for UTI's but has adverse effects on hearing and kidney function? (not sulfonamides) | aminoglycoside
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| This class of antibacterials inhibits the bacteria's ability to metabolize folic acid. | sulfonamide
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| This class of antibacterials could make your teeth grey and cause photosensitivity. | tetracycline
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| This is the prototype drug most commonly used for combating tuberculosis. | isoniazid (INH, Nydrazid are the brand names)
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| This anesthetic drug can interfere with the antibacterial activity of sulfonamides. | benzocaine
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| This antibiotic prototype is a cell wall inhibitor. Its third and fourth generations are able to enter the CSF and treat CNS infections. Name its pharm class too please! | Prototype = cefotaxime
Pharm class = Cephalosporins
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| Oxacillin, ampicillin and carbenicillin are all drugs in this class of antibiotics. | Penicillin
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| This class of antibacterial must be administered with a full glass of water and any antacids must be ingested with a difference of 1 to 3 hours from the antibiotic. They can cause esophageal burning. | tetracyclines
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| This drug class inhibits protein synthesis and it is not tetracyclines nor amino glycosides. | macrolides
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| A Z-pak is in this class of drugs, and these antibacterials can increase the effects of warfarin. They must be taken on an empty stomach and with a full glass of water. | macrolides
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| Gentamicin is this class of antibiotics prototype drug. | aminoglycosides
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| What is a good nursing intervention for nephrotoxicity? | Drink more water.
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| This class of antibiotics are very powerful, but have serious side effects. They are mostly prescribed for serious systemic infections caused by aerobic, gram-negative assholes. Ototoxicity and nephrotoxicity are serious concerns. | aminoglycosides
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| Ciprofloxacin is the prototype of this class of antibacterials. | fluoroquinolones
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| You must wait at least 4 hours before taking antacids with this class of drug. Name the prototype too if you are up to it! | Class= fluoroquinolone
Prototype = ciprofloxacin
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| What makes an antibiotic bacteriostatic instead of bacteriocidal? | Bacteriostatic limit the growth of the bacteria while bacteriocidal kill the bacteria.
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| This class of antibacterial's prototype drug is trimethoprim. | sulfonamides
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| What is the testing called when the doctor takes a sample of your bacteria and grows it in the lab in order to see what antibacterials work best upon it? | Culture and sensitivity testing.
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| This antibiotic is contraindicated in children younger than 8. | tetracycline
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| When taking this drug, the patient must report any unusual heel, lower leg or calf pain and should avoid milk and antacids when taking it. | ciprofloxacin
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| A black box warning on this drug warns about tendon rupture! | ciprofloxacin
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| This antifungal is an IV only and is used for only the most extreme cases because of its severe toxicity. | Amphotericin B
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| These are the safest, most prescribed topical anti fungals (mouthwash and paint on formulas too for thrush). Their class is polyene. What is their prototype drug? | nystatin (Mycostatin is the brand name)
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| The prototype drug for the treatment of malaria is - | chloroquine
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| Worms, worms, worms, wiggly worms, worms and more worms that may be crawling in your body right now, you dirty people, could be treated with this prototype drug. | mebendazole (Vermox is the brand name)
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| Protozoans hate this prototype drug. | metronidazole (Flagyl is the brand name)
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| Fungal infections are referred to by this word. | Mycoses
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| The most common drug prescribed for herpesvirus infections is called. | acyclovir
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| NRTI stands for. | Nucleoside Reverse Transcriptase Inhibitors
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| NNRTI stands for. | Non-Nucleoside Reverse Transcriptase Inhibitors
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| Another word for a virus's protein coat. | Capsid
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| HAART stands for. | Highly Active AntiRetroviral Therapy.
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| LTIA stands for. | Let's Talk In Acronyms
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| In the current HIV therapy, this drug is the NNRTI. | nevirapine (Viramune)
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| True or False: Acyclovir is an effective treatment for Epstein-Barr Virus. | False
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| What is a major adverse effect the nurse must monitor for, in the patient, when giving zidovudine (Retrovir, AZT)? | Reduced number if red and white blood cells.
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| Do not look this antineoplastic prototype in the eye, it will fuck you up! | vincristine (Oncovin)
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| The pharmacologic class of drugs that cyclophosphamide (Cytoxan) belongs to. | alkylating agents
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| The pharmacologic class of drugs that fluorouracil (Adrucil) belongs to. | antimetabolites
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| The pharmacologic class of drugs that vincristine sulfate (Oncovin) belongs to. | plant extracts
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| The pharmacologic class of drugs that methotrexate (Rheumatrex, trexall) belongs to. | antimetabolites
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| The pharmacologic class of drugs that bleomycin (Blenoxane) belongs to. | antitumor antibiotics
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| The pharmacologic class of drugs that etoposide (VePesid) belongs to. | plant extracts
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| The pharmacologic class of drugs that tamoxifen (Nolvadex) belongs to. | hormones and hormone antagonists
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| The pharmacologic class of drugs that levamisole (Ergamisol) belongs to. | biologic response modifiers
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| The pharmacologic class of drugs that streptozocin (Zanosar) belongs to. | alkylating agents
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| How do antimetabolites work? | They disrupt critical pathways in the cancer cells.
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| How do alkylating agents work? | They change the shape of DNA and keep it from functioning normally.
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| Which one of these drugs would not be used for prostate cancer? A) leuprolide B) vinorelbine tartate C) megastrol D) Bicalutamide | B) vinorelbine tartate
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