Antiarrhythmic Drugs USMLE 1
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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| Quinidine | show 🗑
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| show | cinchonism - headache, tinnitus thrombocytopenia, torsades de points due to inc QT interval
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| Procainamide | show 🗑
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| show | reversible SLE-like syndrome
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| show | Class IA Sodium Channel blocker, inc AP duration, inc effective refractory period, inc qt interval
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| show | Slow or block conduction in depolarized cells, dec slope of phase 0 depolarization, inc threshold for firing in abnormal pacemaker cells.
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| Lidocaine | show 🗑
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| show | local anesthetic, CNS stimulation/supression, cardi depression
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| Mexiletine | show 🗑
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| show | Class IB sodium channel blocker, dec AP duration, affect ischemic or depolarized purkinje and ventricular tissue. Useful in acute ventricular arrhythmias (post MI) and in digitalis induce arrhythmias
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| Phenytoin | show 🗑
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| Flecainide | show 🗑
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| Class 1C Tox | show 🗑
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| Hyperkalemia and Class 1 drugs | show 🗑
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| show | Class 1C. no effect of AP duration. Useful in V-tachs that progress to VF and in intractable SVT. Use on patients without structural abnormalities.
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| show | Class 1C. no effect of AP duration. Useful in V-tachs that progress to VF and in intractable SVT. Use on patients without structural abnormalities.
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| show | B-blocker (class 2) dec camp, dec calcium currents, dec slope of phase 4 in pacemakers. AV node most sensitive, inc PR interval. Use v-tach, SVT, slow ventricular rate during a-fib and a-flutter.
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| show | B-blocker (class 2) dec camp, dec calcium currents, dec slope of phase 4 in pacemakers. AV node most sensitive, inc PR interval. Use v-tach, SVT, slow ventricular rate during a-fib and a-flutter. Esmolol very short acting.
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| Metoprolol | show 🗑
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| show | B-blocker (class 2) dec camp, dec calcium currents, dec slope of phase 4 in pacemakers. AV node most sensitive, inc PR interval. Use v-tach, SVT, slow ventricular rate during a-fib and a-flutter.
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| show | impotence, exacerbation of asthma, cardio effects = bradycardia, av block, CHF. CNS effects = sedation and sleep alterations. May mask signs of hypoglycemia. Treat overdose with glucagon.
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| Metoprolol Tox | show 🗑
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| Sotalol | show 🗑
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| Sotalol Tox | show 🗑
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| show | K channel blocker Class III. Inc AP duration, Inc ERP, Inc QT interval
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| show | K channel blocker Class III. Inc AP duration, Inc ERP, Inc QT interval
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| show | K channel blocker Class III. Inc AP duration, Inc ERP, Inc QT interval
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| show | torsades
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| Bretylium Tox | show 🗑
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| show | pulmonary fibrosis, hepatotoxicity, hypothroidism/hyperthyroidism
(has class 1, 2, 3, 4, effects because it alters the lipid membrane.
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| show | Calcium channel blocker Class IV. dec conduction velocity, inc ERP, inc PR interval. Used in prevention of nodal arrhythmias (SVT)
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| show | Calcium channel blocker Class IV. dec conduction velocity, inc ERP, inc PR interval. Used in prevention of nodal arrhythmias (SVT)
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| Adenosine | show 🗑
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| show | Flushing, hypotension, chest pain
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| Digoxin | show 🗑
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| Digoxin Tox | show 🗑
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Created by:
sweetlu32
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