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grcc bi240 healing

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Question
Answer
fibrosis   occur due to complications or chronic inflammation.  
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healing by first intention   wound cleaned, edges quickly approximated and sutured = less scaring  
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Healing by second intention   Wounds heal from inside out; there is a large break in tissue, jagged edges, more inflammation & longer healing time.  
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healing process has how many phases?   4: inflammatory, migratory, proliferative & maturation  
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Inflammatory phase   blood clot forms and seals area where proliferation happens, fibroblasts form and phagocytosis.  
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Migratory phase   Epitheleal cells continue to migrate and proliferate, granulation tissue  
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in migratory phase granulation tissue forms   beneath the the scab.  
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Proud flesh   granulation tissue.  
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Proliferative phase   Epi increases in thickness, collagen fibers in regular patterns, fibroblasts supplied, debris/fibrin/leukocytes disappear  
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maturation phase (remodeling)   Scab sloughs off, epi normal, collagen more organized, fibroblasts disappear, vascular restored  
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When does scar fade?   When capillaries decrease; red to white  
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Complications of scar tissue   puckering of skin, keloid formation, adhesion  
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complications of a scar   it can pucker causing a distortion  
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complications of adhesion   can cause obstruction (i.e. bowel twisting)  
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co-morbility   delayed healing due to other health problems such as DM or cancer.  
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Complications of healing   loss of funcion  
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What is the worst complication of healing?   contractures/obstructions  
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Hypertrophic scar formation   keloid  
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Common contracture   scar tissue that forms where you can't bend or move extremity.  
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Created by: Wends1984
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