Antiemetic, Antinausea drugs
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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show | Vomiting center (VC)
Chemoreceptor trigger zone (CTZ)
Both located in the brain
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what are three pathways that lead to CTZ | show 🗑
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show | Bind to & block acetylcholine (ACh) receptors in the inner ear labyrinth
Block transmission of nauseating stimuli to CTZ
Also block transmission of nauseating stimuli from the reticular formation to the VC
scopolamine- used for motion sickness
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how do antihistamines help as antiemetics | show 🗑
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how do antidopaminergic help as antiemetics | show 🗑
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show | Block dopamine in the CTZ
Also stimulate peristalsis in GI tract, enhancing emptying of stomach contents
Also used for GERD, delayed gastric emptying
metoclopramide (Reglan)- Long-term use may cause irreversible tardive dyskinesia
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how do serotonin blockers help as antiemetics | show 🗑
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What are tetrahydrocannabinoids | show 🗑
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what herbal products act as antiemetics | show 🗑
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all antiemetics can do what | show 🗑
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