Antiemetic, Antinausea drugs
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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| what are areas in body that trigger vomiting | show 🗑
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| what are three pathways that lead to CTZ | show 🗑
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| show | Bind to & block acetylcholine (ACh) receptors in the inner ear labyrinth
Block transmission of nauseating stimuli to CTZ
Also block transmission of nauseating stimuli from the reticular formation to the VC
scopolamine- used for motion sickness
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| how do antihistamines help as antiemetics | show 🗑
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| how do antidopaminergic help as antiemetics | show 🗑
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| show | Block dopamine in the CTZ
Also stimulate peristalsis in GI tract, enhancing emptying of stomach contents
Also used for GERD, delayed gastric emptying
metoclopramide (Reglan)- Long-term use may cause irreversible tardive dyskinesia
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| show | Block serotonin receptors.
Used for patients receiving chemotherapy, postop nausea and vomiting. "On Dancer, On Prancer....Santa is bringin Zofran"
dolasetron (Anzemet), granisetron (Kytril), ondansetron (Zofran), palonosetron (Aloxi)
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| show | Major psychoactive substance in marijuana
Inhibitory effects on reticular formation, thalamus, cerebral cortex
dronabinol (Marinol)
Used for nausea & vomiting associated with chemotherapy, & anorexia associated with weight loss in AIDS patients
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| what herbal products act as antiemetics | show 🗑
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| all antiemetics can do what | show 🗑
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Created by:
palmerag
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