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Antiemetic, Antinausea drugs

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Question
Answer
what are areas in body that trigger vomiting   show
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what are three pathways that lead to CTZ   show
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show Bind to & block acetylcholine (ACh) receptors in the inner ear labyrinth Block transmission of nauseating stimuli to CTZ Also block transmission of nauseating stimuli from the reticular formation to the VC scopolamine- used for motion sickness  
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how do antihistamines help as antiemetics   show
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how do antidopaminergic help as antiemetics   show
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show Block dopamine in the CTZ Also stimulate peristalsis in GI tract, enhancing emptying of stomach contents Also used for GERD, delayed gastric emptying metoclopramide (Reglan)- Long-term use may cause irreversible tardive dyskinesia  
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show Block serotonin receptors. Used for patients receiving chemotherapy, postop nausea and vomiting. "On Dancer, On Prancer....Santa is bringin Zofran" dolasetron (Anzemet), granisetron (Kytril), ondansetron (Zofran), palonosetron (Aloxi)  
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show Major psychoactive substance in marijuana Inhibitory effects on reticular formation, thalamus, cerebral cortex dronabinol (Marinol) Used for nausea & vomiting associated with chemotherapy, & anorexia associated with weight loss in AIDS patients  
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what herbal products act as antiemetics   show
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all antiemetics can do what   show
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Created by: palmerag
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