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parts of integumentary system

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Protection – Chemical & Biological • Low pH of skin secretions (acid mantle) • Bactericidal substances in sebum • Human defensin- natural antibiotic produced by skin cells • Melanin to protect against UV damage • Macrophages & Langerhans’ cells   functions of integumentary system  
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Mechanical • Keratinized cells to form a barrier • Glycolipids make a waterproof barrier   functions of integumentary system  
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Body Temperature Regulation – Evaporation of sweat cools the body – Constriction of dermal blood vessels causes skin to drop in temperature slowing passive heat loss to the environment   functions of integumentary system  
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Sensation – Meissner’s corpuscles & Merkel discs – a caress – Pacinian receptors – deep pressure receptors   functions of integumentary system  
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Metabolic Functions – Vitamin D production – Activation of steroid hormones   functions of integumentary system  
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Blood Reservoir   function of integumentary system  
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Excretion   function of integumentary system  
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The skin has two distinct regions, what are they?   The epidermis and dermis.  
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– composed of epithelial cells (avascular)   epidermis  
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– fibrous connective tissue   dermis  
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-composed of adipose and areolar connective tissue, is below the dermis. -Functions as a shock absorber & insulator. -Where one gains weight.   hypodermis  
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Characteristics - stratified squamous epithelia - four cell types(keratinocytes, meloninocytes, langerhans' cells, and merkel cells.   characteristics of epidermis  
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-produces keratin to give epidermis protective properties   keratinocytes  
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– spider shaped cells, produce melanin to protect nucleus from UV damage melanin collects in melanosomes   melanocytes  
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– star-shaped cells, arise from bone marrow to help activate the immune system aka: epidermal dendritic cells   langerhans' cells  
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– spikey hemisphere, functions with a disc like sensory nerve ending to function as a sensory receptor   merkel cells  
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Characteristics four to five layers (deep to superficial) : stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, & stratum corneum.   epidermis characteristics  
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aka: stratum geminativum – rapid cell division   stratum basale  
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web-like system of intermediate filaments   statum spinosum  
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accumulates keratohyaline granules to help with keratin production and lamellated granules to help slow water loss   stratum granulosum  
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(absent in thin skin) - rows of clear, flat dead keratinocytes   stratum lucidum  
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keratin found in this layer; provides protection and a waterproof boundary; 3⁄4 of the skin is made from this layer   stratum corneum  
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Layers of the skin in order.   Stratum Corneum, Stratum Lucidum, Stratum Granulosum, Stratum Spinosum, & Stratum Basale.  
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Characteristics -strong, flexible connective tissue; “your hide” -cell types include: fibroblasts, WBC, & macrophages -two layers: papillary layer and reticular layer   characteristics of dermis  
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Papillary Layer -collagen fibers provide strength & resiliency -elastic fibers allow stretching -dermal papillae indent the superior surface into the epidermis -Meissner’s corpuscles-touch receptors   characteristics of dermis  
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Reticular Layer -dense irregular connective tissue -Pacinian corpuscles- pressure receptors   characteristics of dermis  
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Characteristics -lies deep to the dermis -consists of adipose & areolar connective tissue -anchors skin to underlying structures -energy storage   characteristics of hypodermis  
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Three pigments contribute to skin color, what are they?   Melanin, carotene and hemoglobin  
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is produced in the skin. It ranges from yellow to reddish-brown to black.   melanin  
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All people have the same number of melanocytes. Skin color is determined by the color of melanin produced, the amount produced and the retention rate. Black individuals produce more melanosomes than fair skinned individuals.   characteristics of melanin& skin color  
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is yellow to orange. It accumulates in the hypodermis and the stratum corneum. It is found in carrots, sweet potatoes, broccoli, pumpkin, etc.   Carotene  
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is found in the RBC. Fair skinned people have little melanin, so oxygenated hemoglobin is seen and gives a pink hue to the skin.   hemoglobin  
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- Eccrine sweat glands - produces sweat, found throughout the skin surface - abundant on palms, soles of feet and forehead   Sweat Glands or Sudorifierous Glands  
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- found in the axillary and groin areas - in addition to normal sweat components, contains fatty substances & protein - more viscous than sweat - when broken down by bacteria, it is responsible for body odor   Apocrine sweat glands  
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(holocrine) - produce cerumen, earwax   Ceruminous Glands  
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(merocrine) - specialized sweat gland that produces milk   Mammary Glands  
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-(oil) - holocrine glands - found all over the body except palms & soles of feet - produce sebum - lubricates hair & skin; keeps hair & skin soft - seborrhea “cradle cap"– overactive sebaceous gland   sebaceous glands  
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- composed of dead keratinized cells - two regions: the shaft & the root   Hair  
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If the shaft is . . . -flat & ribbonlike, the hair is kinky -oval, the hair is silky and wavy -round, the hair is straight & may be coarse   characteristics of the shaft of the hair  
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3 concentric layers of the hair shaft, what are they?   medulla, cortex, & cuticle  
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- central core; large cells and air spaces   medulla  
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- several layers of flattened cells   cortex  
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- single layer of cells that overlap   cuticle  
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it comes from the production of melanin at the base of the hair follicle.   Root of the Hair Color  
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- deep end of the follicle   Hair Bulb  
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- sensory nerve endings wrapped around the hair bulb   Root Hair Plexus  
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- supplies nutrients   Dermal Papilla  
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*Outer Sheath- connective tissue *Glassy Membrane- thickened basement membrane *Inner Sheath- epithelial tissue   Wall of Hair Follicle  
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- active growing region of a hair   Hair Matrix  
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– smooth muscle associated with a hair; allows the hair to stand on end; responsible for goose bumps   arrector pili muscle  
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- scale-like modifications of the epidermis   Nails  
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Types of white blood cells   basophils, neurtophils, macrophages, and fibroblasts  
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– make histamines – Dilate blood vessels – Make blood vessel wall more permeable   basophils  
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–phagocytic – Attack the wound   Neutrophils  
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– very phagocytic – Cleans up the would depris   Macrophages  
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–buildsnew dermis – Stratum basale layer   fibroblasts  
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A – Asymmetry (symmetrical, asymmetrical) B – Border Irregularities (even edges, uneven edges) C – Color (one shade, two or more shades) D – Diameter (smaller than 6mm, larger than 6mm)   skin cancer ABCD rule  
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3 types of burns, what are they?   first, second, and third degree burns  
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- only epidermis is damaged   First Degree  
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- blistering; epidermis and upper part of dermis is damaged   second degree  
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- full thickness burns; involves the entire thickness of the skin; looks gray-white or cherry red to blackened   third degree  
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Disease of the skin – Melanocytes do not produce enough (or any) melanin – Albino skin is translucent white and eyes are pink   Albinism  
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Disease of the skin – Absence of melanocytes in patches (could be patch of white hair) – Wandering Vitilago – melanocytes start and stop working   Vitilago  
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