Microbe Virulence and Human Resistance chapter 24
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Relative power and degree of pathogenicity possessed by organisms to produce disease | virulence
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condition characterized by the multiplication of bacteria in the blood and commonly known as blood poisoning | Septicemia
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a foreign substance that stimulates the formation of antibodies that interact specifically with it | antigen
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a living organism or an object that is capable of transmitting infections by carrying the disease agent on its external body part or surface | Mechanical vector
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causative agent of leptospirosis | Leptospira
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bacterial toxin confined within the body of a bacterium freed only when the bacterium is broken down; found only in gram negative bacteria | endotoxin
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the natural habitat of a disease- causing organism | reservoir
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causative agent of tetanus | Clostridium tetani
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an organism that exists as part of the normal flora but may become pathogenic under certain conditions | opportunists
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the organism from which a microorganism obtains its nourishment | host
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infection caused by a different organism that the one causing the primary infection | secondary infection
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originating outside the body, an organ, or a part of the body; | exogenous infection
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causative agent of typhus fever | Rickettsia typhi
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glycoprotein substances developed in response to and interacting specifically with an antigen | antibodies
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one in which organisms are originally confined to one area but enter the blood or lymph vessel and spread to other parts of the body | focal infection
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a poisonous substance of plant, animal, bacterial, or fungal origin | toxins
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causative agent of Rocky Mountain spotted fever | Rickettsia ricketsii
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an arthropod in which the disease- causing organism multiplies or develops within the arthropod prior to becoming infective for a susceptible individual | biological vector
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causative agent of plague | Yersima pestis
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causative agent of food poisoning | Staphylococcus aureus
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causative agent of botulism | Clostridium botulinum
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causative agent of diphtheria | Corynebacterium diphtheriae
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causative agent of pertussis | Bordetella pertussis
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infection caused by two or more organisms | mixed infection
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causative agent of parrot fever | Chlamydia psittaci
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causative agent of Lyme disease | Borrelia burgdorferi
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causative agent of anthrax | Bacillus anthracis
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reducing or abolishing pathogenicity | attenuation dilution or weakening of the virulence of a microorganism
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an original infection from which a second one originates | original infection
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the state of producing or being able to produce pathological changes and disease | pathogenicity
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a microorganism capable of producing disease | pathogen
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microorganisms virulent enough to resist pharmaceuticals designed to reduce disease is reffered to as | drug- fast
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infection caused by germs lodging and multiplying at one point in a tissue and remaining in that tissue | local infection
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a toxin, generally a protein, produced by a microorganism and excreted into its surrounding medium | exotoxin
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the act of introducing disease germs or infectious material into an area or substance is known as | contamination
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causative agent of tularemia | Francisella tularensis
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causative agent of cholera | Vibrio cholerae
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the distribution throughout the body of poisonous products of bacteria growing in a focal or local site,producing generalized symptoms | toxemia
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causative agent of Q fever | Coxiella burnetti
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an infection that becomes systemic | general infection
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guidelines designed to protect workers with occupational exposure to bloodborne pathogens | Universal precautions
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any inanimate object to which infectious material adheres and can be transmitted | indirect contact
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an organism capable of producing disease | Pathogen
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any inanimate objects which infectious material adheres and can be transmitted | Fomite ex: table scaples...
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relatives powers and degree of pathogenicity possesed by organisms to produce disease | virulence
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a marker on every cell icluding invading pathogens by which the body recognizes unknown cells or disese- causing organisms | Antigen
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the organism from which a parasite obtains its nourishment | host
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a chemical enzyme in the body that uses water to break down the peptidoglycan layer in prokaryatic pathogens | Lysozyme
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the state or conditon in which the body or part of the body is invaded by a pathogenic agent that , under favorable conditions multiplies and produce injurious effects | infection
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infection caused by bacteria that are normally nonpathogenic and that normally inhabit the digestive tract | endogenous infection
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a carrier usually an insect or other arthropod , that transmits the the causative organisms of disease from infected individuals | vector
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portal of exit and entry allow the spread of pathogens causing tetanus, malaria african sleeping sickkness , typhoid fever turberculosis, rabies dysentry typus fever and butonic plague | skin and mucous membranes
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The four factors that influence the occurence of disease | 1) The virulence of the organisms 2)The portal of entry of the pathogen 3)the number of organisms present 4) the resistance of the host
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organism that are noriginally confined to one area but enter the blood or lymph vessels and spred to other pars of the body | Focal infection
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a general infection its also known as | systemic infection ex: Measles is a systemic infection
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an acute infection is also known as | primary infection
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the presence of VIRUSES in the blood | Viremia
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the 3 mecanism of direct transmission of disease | 1) physical contact 2)droplet infection 3)congenital transmission
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Mode of indirect transmissiom of disease | food, milk, fomites, water , soil,
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disease that are communicable from animals | Zoonoses
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Glycoprotein substance developed in response to, and interacting specifically with an antigen. Also known as immunoglobulin | antibody
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A method of asexual reproduction in bacteria in which the cell splits into two parts, each of which develops into a complete individual. (simple transverse division | binary fission
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An arthropod vector in which the disease causing organism multiplies or develops within the arthropod prior to becoming infective for a susceptible individual. | biological vector
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five portals of entries and exit which pathogens may enter or exit the body | 1)the skin and mucous membranes 2)the respiratory tract 3)the digestive tract 4) the genitourinary tract 5) placenta
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one of the most important and effective barriere against infection | skin
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the process by which the epithelial layer of the skin continously dies and are replaced with new cells | necrobiosis mechanichal defense of the skin
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Innate immunity is also known as | natural immunity
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natural active immunity is the result | developing a disease and recovering from it
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natural passive immunity is the result | of placental transfert of antibodies in the uterus ex mother to the child from breast milk
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artificial passive immunity | the injection of antibodies in the forms of immune serums
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artificial active immunity | result of receiving vaccination
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the sum total of body mechanisms | resistance
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the skin as a mechanical defense system known as | Necrobiosis
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to remove foreign that matter that enter the body, the body initiates a physiologycal response known as | inflammation
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chemicals capable of breaking down forein cells and debris | phagocytes
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the cardinal signs and symptoms of inflammation | heat, swelling pain redness , loss of function
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A disease that occurs continuously in a particular region but has low mortality | Epidemic
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The state or condition in which the body or a part of it is invaded by pathogenic agents, that under favorable conditions, multiplies and produces injurious effects | Infection
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A disease affecting the majority of the population of a large region or one that is epidemic at the same time in many different parts of the world | Pandemic
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