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Gastrointestinal System

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Question
Answer
Abnormal condition characterized by the inability of a muscle, particularly the cardiac sphincter of the stomach, to relax   achalasia  
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abnormal condition characterized by the absence of hydrochloric acid in the gastric secretions   achlorhydria  
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surgical joining of two ducts or blood vessels to allow flow from one to the other   anastomosis  
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general ill health and malnutrition marked by weakness and emaciation   cachexia  
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oncofetal glycoprotein antigen found in colonic adenocarcinoma and other cancers; also found in nonmalignant conditions   carcinoembryonic antigen (CEA)  
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partial or complete separation of the wound edges   dehiscence  
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difficulty in swallowing   dysphagia  
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state in which the patient’s viscera protrude through a disrupted wound   evisceration  
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an increase in the seriousness of a disease or disorder   exacerbation  
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vomiting blood   hematemesis  
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infolding of one segment of the intestine into the lumen of another segment   intussusception  
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a white patch in the mouth or on the tongue   leukoplakia  
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space within an artery, vein, intestine, or tube   lumen  
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abnormal, black tarry stool containing digested blood   melena  
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blood that is hidden or obscured from view   occult  
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sign or symptom specific to a disease or condition   pathognomonic  
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a decrease in the severity of a disease or any of its symptoms   remission  
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excessive fat in the feces   steatorrhea  
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combining form meaning a mouth or opening   stoma  
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ineffective and painful straining with defecation   tenesmus  
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twisting of the bowel on itself, causing intestinal obstruction   volvulus  
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contrast medium used for upper GI study   barium  
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test used to detect any abnormal structural conditions of the upper GI tract   upper GI series  
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how quickly must the gallon of Golytely be taken if used for upper GI series?   2 hours  
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what color does barium turn stool?   white, or light in color  
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why is it important for a patient to increase fluid intake after UGI series?   to expel all the barium and prevent constipation  
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in this test stomach contents are aspirated to determine the amount of acid produced by the parietal cells in the stomach   tube gastric analysis  
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how is a sample for tube gastric analysis collected?   via NG tube  
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diagnostic test using an endoscope to directly examine the esophagus, stomach, and duodenum   EGD  
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some issues that can be detected or address by EGD   tumors, varices, mucosal inflammations, hiatal hernias, polyps, ulcers, H. pylori, strictures, obstructions  
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how long must a patient remain NPO following an EGD?   until gag reflex returns  
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what are the signs and symptoms of espophageal, gastric, or duodenal perforation?   abdominal pain and tenderness, guarding, bleeding from mouth, melena, hypovolemic shock  
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a more thorough version of the upper GI which can detect anatomical abnormalities such as hiatal hernia, left atrial dilation, aortic aneurysm, paraesophageal tumors   barium swallow  
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this can be used in place of barium in cases where GI bleed is present or suspected   gastrografin  
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this test is used to reproduce the symptoms of esophageal reflux and can be used to differential esophageal pain from angina pectoris   berstein test (esophageal function study)  
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how is a positive berstein test determined?   the patient experiences a recurrence of pain when HCl is instilled into the esophagus  
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what should be suspected if occult blood is detected in the stool?   benign or malignant GI tumor  
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this study allows visualization of the lower GI tract and the collection biopsy specimens of tumors, polyps, or ulcerations of the anus, rectum, and sigmoid colon   sigmoidoscopy  
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test used to detect structural abnormalities (polypes, tumors, diverticula, and positional abnormalities) of the lower GI using barium as a contrast medium   barium enema  
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what is a possible complication of failure to expel all barium quickly from the GI tract   impaction  
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use of a fiberoptic scope to examine the entire colon   colonoscopy  
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this diagnostic test is used to test for the presence of bacteria, ova, and parasites   stool culture  
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what solutions can be used in an enema for the purpose of collecting a stool specimen for culture   normal saline or tap water  
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stool cultures should be taken before the administration of this contrast medium   barium  
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accumulation of fluid and albumin in the peritoneal cavity   ascites  
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a hand flapping tremor in which the patient stretches out an arm and hyperextends the wrist with the finger separated, relaxed, and extended   asterixis  
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a complex of longitudinal, tortuous veins at the lower end of the esophagus   esophageal varices  
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excess formation of gases in the stomach or intestine   flatulence  
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a type of brain damage caused by liver disease and consequent ammonia intoxication   hepatic encephalopathy  
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inflammation of the liver caused by viruses, bacteria, and noninfectious causes of liver inflammation   hepatitis  
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yellow discoloration of the skin, mucous membranes, and sclera of the eyes, caused by greater than normal amounts of bilirubin in the serum   jaundice  
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an obstruction or closing off   occlusion  
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a procedure in which fluid is withdrawn from the abdominal cavity   paracentesis  
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tissue of an organ as distinguished from supporting or connective tissue   parenchyma  
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small, dilated blood vessels with a bright red center point and spiderlike branches   spider telangiectases  
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stools that contain fat   steatorrhea  
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this system includes the liver, gall bladder, cystic, hepatic, and common bile ducts and the pancreatic duct   biliary system  
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bile travels through the hepatic duct to the _________ for storage   gall bladder  
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this organ is responsible for fat metabolism, production of clotting factors, cholesterol and albumin manufacture, blood filtration, conversion of ammonia to urea   liver  
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this organ is a sac located on the right inferior surface of the liver   gallbladder  
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the storage organ for bile   gallbladder  
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the three enzymes present in pancreatic juice   protease, lipase, amylase  
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pancreatic juice aids in the digestion of what three substances?   proteins, fats, and carbs  
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what is the purpose of the sodium barcarbonate in the pancreatic juice?   to neutralize stomach acids  
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Elevated levels of this cause jaundice, which is the most common sign of a liver disorder   bilirubin  
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normal levels of total bilirubin   0.1 to 1.0 mg per dl  
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normal values of aspartate aminotransferase(AST)   0 to 35 iu per L  
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liver enzyme that becomes elevated in MI, hepatitis, cirrhosis, hepatic necrosis, hepatic tumor, acute pancreatitis, acute renal disease and acute hemolytic anemia   aspartate aminotransferase (AST)  
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normal values of alanine aminotransferase(ALT)   4 to 36 IU per L  
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liver enzyme that becomes elevated in hepatitis, cirrhosis, hepatic necrosis, hepatic tumors, and hepatotoxic drugs   alanine aminotransferase(ALT)  
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normal values of lactic dehydrogenase   100 to 190 IU per L  
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liver enzyme that becomes elevated in MI, pulmonary infarction, hepatic disease, pancreatitis, hemolytic anemia and skeletal muscle disease   lactic dehydrogenase(LDH)  
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normal values of alkaline phosphatase   30 to 120 IU per ml  
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liver enzyme that becomes elevated in obstructive disorders of the biliary tract, hepatic tumors, cirrhosis, hyperparathyroidism, metastatic tumor in bones, and healing fractures   alkaline phosphatase  
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normal values of Gamma glutamyltransferase(Gamma GT)   male or female over 45:8 to 38 U per L; female under 45:5 to 27 U per L  
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liver enzyme that becomes elevated in liver cell dysfunction, hepatitis, cirrhosis, hepatotoxic drugs, MI, and congestive heart diseases   Gamma glutamyltransferase (Gamma GT)  
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normal value for prothrombin time   11.0 to 12.6 seconds  
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an elevation in this lab value indicates an increased clotting time that can be caused by liver disease (inability to synthesize clotting factors) or vitamin K deficiency   PT  
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this lab value can assess the functional status of the liver by measuring the products that are synthesized there, specifically albumin   serum protein test  
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low values in this laboratory study can be the result of nephritic syndrome, ascites, or inadequate protein in diet as well as liver dysfunction   serum proteins  
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in liver dysfunction, blood levels of this chemical can rise leading to hepatic encephalopathy   ammonia  
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normal values for serum ammonia   10 to 80 ug per dl  
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serum ammonia measurements may be affected by these prescription drugs   antibiotics  
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a diet high in this substance stimulates emptying of the gallbladder   fat  
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in this diagnostic study, radiographic dye is injected intravenously, concentrated by the liver, and secreted into the bile duct   intravenous cholangiography  
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this diagnostic study allows radiographic visualization of the hepatic and common bile ducts if the cystic duct is patent   intravenous angiography  
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in this diagnostic study, the common bile duct is directly injected with dye   operative cholangiography  
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this diagnostic test is used to identify retained stones in a postoperative cholecystectomy patient   t tube cholangiography  
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diagnostic study used to detect structural changes in the liver; uses gamma ray radiation   radioisotope liver scanning  
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in this diagnostic procedure a needle is inserted directly into the liver to remove tissue   needle liver biopsy  
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how should a patient be positioned following needle liver biopsy?   on right side for 2 hours, then flat for 12 to 14 hours  
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fiberoptic scope inserted through the GI tract into the duodenum used to diagnose pancreatic dysfunction, evaluate obstructive jaundice, remove common bile duct stones and place biliary and pancreatic duct stents   endoscopic retrograde cholangiopancreatography (ERCP)  
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laboratory values of this increase 12 hours after onset of pancreatic disease, but return to normal within 48 to 72 hours   amylase  
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normal amylase values   25 to 125 U per L  
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laboratory values of this are elevated in acute pancreatitis   lipase  
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normal lipase values   0 to 110 U per L  
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this procedure is used to establish a diagnosis of pseudocyst, pancreatitis, and pancreatic abcess   ultrasound  
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a noninvasive but accurate imaging study used to diagnose pancreatic inflammation, tumor, cyst formation, ascites, aneurysm, and cirrhosis of the liver   CT scan  
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incurable sores of the mouth and lips ranging in size from 0.5 to 3cm   cold sores, canker sores, aphtous ulcers  
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medical treatment for cold sores, canker sores, and aphthous ulcers   antiinflammatory agents, topical agents, debriding agents  
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anti   inflammatory agent commonly used in cold sores, canker sores, and aphthous ulcers  
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when and how often should amlexanox (aphthasol) be applied?   as soon after noticing symptoms as possible; 4x per day following oral hygiene  
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dental decay caused by dental plaque, poor nutrition, acids, and heredity   dental caries  
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patient teaching for dental caries should include   proper nutrition and proper oral hygiene techniques  
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infection of the oral cavity by the fungus Candida; more frequent in leukemia, diabetes, antibiotics use, and steroids   candidiasis (thrush)  
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treatment for candidiasis   nystatin, amphotericin B, hydrogen peroxide rinse (50%) or saline rinse, ketoconazole  
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side effects of amphotericin B (fungizone)   headache, hypotension, NVD, nephrotoxicity, hypokalemia  
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nystatin oral suspensions or lozenges should be continued for how long following resolution of symptoms?   48 hours or until cultures are negative  
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what common GI medications should not be administered within two hours of ketoconazole?   H2 antagonists or antacids  
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topical analgesic overdose is toxic to which two target organs?   brain and heart  
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GERD is caused by what?   backflow of stomach content  
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what are the two most frequent complaints leading to a diagnosis of GERD?   retrosternal pain after meals and regurgitation  
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GERD and this condition have very similar symptoms   angina pectoris  
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what lifestyle changes can reduce symptoms of GERD?   stop smoking, no strenuous exercise, sleep with head elevated, eat smaller meals, quit drinking, don’t eat close to bedtime, limit caffeine  
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what causes achalasia?   spasm of the cardiac sphincter  
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what are some signs and symptoms of achalasia?   difficulty swallowing, regurgitation, chest pain, nocturnal cough, weight loss  
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treatment of achalasia focuses on what two outcomes?   dilation of cardiac sphincter and reduction of esophageal pressure  
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inflammation of the lining of the stomach   gastritis  
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common causes of gastritis   alcohol, smoking caffeine, bacteria, viruses, aspirin, nsaids, stress, chemotherapy, radiation therapy, food allergies  
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signs and symptoms of acute gastritis   epigastric pain, nausea, vomiting, headache, anorexia  
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diagnostic tests appropriate for gastritis   occult blood, CBC, gastroscopy  
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treatment for gastritis   antiemetics, antacids, H2 antagonists, antibiotics, fluid and electrolyte replacement  
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ulceration of the mucous membranes of the deeper structures of the GI tract   peptic ulcer disease  
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the two most common sites of peptic ulcers   stomach(gastric), duodenum  
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the two most common causes of peptic ulcers   chronic hyperacidity or mucous reduction  
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this bacteria is found in over 70% of those with gastric ulcers and 95% of those with duodenal ulcers   H. pylori  
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this class of medications can cause gastric injury and lead to the development of peptic ulcers   NSAIDS  
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complications of peptic ulcer disease   hemorrhage and perforation, gastric outlet obstruction  
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diagnostic tests appropriate for peptic ulcer disease   CBC, Upper GI series, esophagogastroduodenoscopy, biopsy, H. pylori  
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medications used to manage peptic ulcer disease   antacids, H2 antagonists, antibiotics, mucosal healing agents, proton pump inhibitors, Prostaglandin E analogue  
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removal of the entire antrum (lower stomach) to eliminate the main stimuli for acid production   antrectomy  
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part of the stomach is removed and the remaining portion of the stomach is connected to the duodenum   gastroduodenostomy  
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a process where the jejunum is anastomosed to the stomach to provide a second outlet for gastric contents and the vagus nerve is severed   gastrojejunostomy and vagotomy  
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removal of the entire stomach and the esophagus is joined to the jejunum   total gastrectomy  
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a procedure in which an incision in the pylorus is opened and then closed to permit the stomach to relax   pyloroplasty  
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treatment of H. pylori usually includes   H2 receptor antagonist or Proton Pump Inhibitor with two antiinfectives for 1  
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antiinfectives used for the treatment of H. pylori   amoxicillin, clarithromycin, metronidazole, doxycycline  
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which antiinfective used in the treatment of H. pylori is contraindicated during pregnancy   tetracycline (doxycycline)  
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which antiinfective used for the treatment of H. pylori is contraindicated in those with a history of seizures or neurological problems?   metronidazole (flagyl)  
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which antiinfective used for the treatment of H. pylori can cause ventricular dysrhythmias and blood disorders?   clarighromycin (biaxin)  
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which antiinfective used in the treatment of H. pylori can cause albuminuria and neurotoxicity?   metronidazole (flagyl)  
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which antiinfective used in the treatment of H. pylori can cause discoloration and softening of the teeth and bones   tetracycline(doxycycline)  
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what food groups and medications should be avoided when administering tetracycline?   milk and dairy products, calcium, antacids, magnesium, sodium bicarb, and other iron supplements  
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Antacids usually contain one of these three ingredients   aluminum, magnesium, calcium  
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some commonly used Histamine H2 antaonists   cimetidine, famotidine (pepsid), nizatidine, ranitidine(zantac)  
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IV dosage of H2 antagonists should be administered slowly to prevent what possible side effect?   bradycardia  
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some commonly used Proton pump inhibitors   esomeprazole(nexium), lansoprazole(prevacid), omeprazole(prolosec), rabeprazole(aciiphex)  
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what time of day should proton pump inhibitors be administered?   morning  
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these two classes of GI medications reduce the secretion of gastric acid   H2 antagonists and proton pump inhibitors  
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degenerative disorder of the liver from generalized cellular damage   cirrhosis  
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what are some common health problems related to cirrhosis?   impaired digestion and metabolism, reduction in protein synthesis, impaired coagulability, fluid-electrolyte imbalances, ascites  
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what would you expect laboratory values of liver enzymes to be in a patient with cirrhosis   elevated  
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what would you expect lab values of serum albumin to be in a patient with cirrhosis?   decreased  
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what would you expect lab values of serum ammonia to be in a patient with cirrhosis?   elevated  
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what would you expect lab values of glucose to be in a patient with cirrhosis?   decreased  
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what would you expect the prothromin time to be in a patient with cirrhosis   prolonged  
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removal or aspiration of fluid from the peritoneum?   paracentesis  
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yellowish discoloration of tissues caused by abnormally high level of bilirubin in blood?   jaundice  
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other than yellow discoloration in the eyes and skin, what are some other symptoms of elevated bilirubin   clay colored stool, deep orange urine color  
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what substances would you expect to be restricted in a patient with cirrhosis?   fluid, sodium, alcohol, fat, protein  
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one way valve moving fluid from peritoneal cavity to superior vena cava   peritoneal jugular shunt (laveen)  
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possible complications of a peritoneal jugular shunt   hemodilution, pulmonary edema, CHF, wound infection, peritonitis, septicemia, shunt occlusion  
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signs and symptoms of hepatic encephalopathy   inappropriate behavior, disorientation, flapping tremors, twitching extremeties, stupor, coma  
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what dietary treatment can help reduce blood ammonia levels?   protein restriction  
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inflammation of the liver resulting from several types of viral agents, exposure to toxic substances or lengthy alcohol abuse   hepatitis  
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signs and symptoms of hepatitis   RUQ pain, NVD, pruritis, jaundice, dark urine, clay colored stools, hepatomegaly  
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the treatment for hepatitis is…   no treatment, palliative care and transmission prevention only  
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Hepatitis B vaccine should not be given to patients with anaphylactic reaction to this substance   yeast  
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formation of stones in the gallbladder   cholelithiasis  
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risk factors for cholelithiasis   overweight, women, pregnant or multiple pregnancies, birth control, diabetes  
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common causes of cholecystitis   obstruction, gallstone, tumor  
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obstruction of the any of the biliary ducts causes…   spasms  
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obstruction of the bile duct leads to bile stasis which causes…   infection and necrosis  
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a hormone secreted by the small intestine each time the person eats fatty food which stimulates the release of bile   cholecystokinin  
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if the gallbladder ruptures or becomes grossly infected, _________ can result   peritonitis  
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a gallstone that has become lodged in and obstructs the common bile duct   choledocholithiasis  
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chronic cholecystitis is treated with   low fat diet  
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the drug of choice for pain control in cholelithiasis   demerol  
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this treatment for cholelithiasis involves the use of shockwaves to break up stone   extracorporeal shock wave lithotripsy  
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this treatment for a gallstone lodged in the common bile duct involves the insertion of an endoscope through the mouth and into the duodenum to capture the stone   endoscopic sphincterotomy  
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the preferred method of gallbladder removal   endoscopic cholecystectomy  
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indications for an open cholecystectomy   extreme inflammation, infection, or large gallstones  
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a biliary drainage tube left in place after cholecystectomy to keep the duct open and drain bile until the inflammation of the common bile duct has resolved   t tube  
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t tube should drain less than this much in an 8 hour period   50ml  
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possible complications of cholecystectomy   jaundice, hemorrhage, peritonitis  
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indication that bile is being deposited normally into the GI tract following cholecystectomy   normal stool and urine color  
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inflammation of the pancreas   pancreatitis  
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common causes of pancreatitis   trauma, disease, inflammatory bowel disease, heredity, alcohol, drugs, refeeding after prolonged fasting or anorexia  
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possible complications of pancreatitis   necrosis, hyperglycemia, hypercalcemia, hemorrhage, peritonitis, abcess, renal failure, sepsis, pleural effusion, blood coagulopathies  
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signs and symptoms of pancreatitis   mid upper abdominal pain, NVD, flatulence, frothy, foul smelling stool, jaundice  
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cullens sign, turners sign, chvosteks sign, and trousseaus sign are all signs of   pancreatitis  
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elevated serum and urine amylase, lipase, and AST-ALT levels, bilirubin levels, WBC’s, glucose with decreased calcium, potassium, and magnesium would be indicative of   pancreatitis  
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the most common cause of chronic pancreatitis   alcoholism  
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when the pancreatic duct is not obstructed what is the treatment for pancreatitis   diet restriction, then gradual advancement, pain control, enzyme replacement, pancreatectomy or transplant  
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most common entry point of intestinal infections into the body   the mouth via contaminated food or water  
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long term use of antibiotic can lead to the death of normal flora and overgrowth of opportunistic bacteria such as…   C. difficile  
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most common sign of intestinal infection   diarrhea  
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primary test for intestinal infection   stool culture  
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treatment for diarrhea   fluid and electrolyte replacement  
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IBS is often related to..   psychological problems  
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most common symptom of IBS   abdominal pain associated with change in bowl habits  
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IBS is diagnosed by…   ruling out other GI disorders  
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In IBS, anticholinergic drugs are used…   to relieve abdominal cramps  
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In IBS, dietary fiber, milk of magnesia, and mineral oil are used to treat   constipation  
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in IBS, antianxiety drugs are used to treat   distress, panic, and depression  
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how many grams per day of dietary fiber should a person with IBS consume?   20  
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inflammation of the colon and rectum characterized by alternating periods of exacerbation and remission   ulcerative colitis  
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the hallmark symptom of ulcerative colitis   diarrhea containing pus and blood  
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10 to 20 liquid stools per day, containing blood, mucus, and pus would be indicative of which inflammatory bowel disease?   ulcerative colitis  
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hallmark sign of this inflammatory bowel disease is a cobblestone appearance in parts of the GI tract   crohns disease  
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severe cases of crohns disease are treated with   corticosteroids  
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patients on long term corticosteroid therapy should be monitored for   infection  
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anticholinergics are contraindicated in patients with   glaucoma, hemorrhage, tachycardia, myasthenia gravis  
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in this procedure the entire colon and rectum are removed and the stoma is located in the right lower quadrant   ileostomy  
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this procedure is done to allow the intestine to repair itself following inflammatory disease, injury, or intestinal surgery   temporary colostomy  
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colostomy placed when there is a debilitating intestinal disease or cancer requiring removal of the colon and rectum   permanent  
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in this “ostomy” material discharged is liquid to semiliquid and contains digestive enzymes   ileostomy  
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in this “ostomy” fecal material discharges is liquid to semi liquid requiring frequent emptying to keep the patient dry and to control odor   ascending colostomy  
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in this “ostomy” fecal material is semi formed, can be irrigated daily to reduce number of bowel movements   transverse colostomy  
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in this “ostomy” fecal material is semi   formed to formed  
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in this “ostomy” fecal material is formed   sigmoid colostomy  
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a pink or red stoma is   healthy  
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a dusky blue stoma indicates   ischemia  
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a brown black stoma indicates   necrosis  
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the four types of hernias   inguinal, femoral, umbilical, and ventral (incisional)  
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most common type of hernia   inguinal  
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inguinal hernias are more frequent in which gender?   male  
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this type of hernia occurs more often in women and easily becomes strangulated   femoral  
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this type of hernia occurs when the rectus muscle is weak and is most common in children   umbilical  
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this type of hernia is due to weakness in the abdominal wall at the site of a previous incision   ventral(incisional)  
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if the protruding structures of a hernia can be replaced into the abdominal cavity via manipulation, it is referred to as   reducible  
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a hernia that cannot be manually manipulated and replaced into the abdominal cavity   irreducible  
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a hernia where blood supply and intestinal flow are occluded   strangulated  
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edema of the hernia and constriction of the muscular opening causing it to be irreducible   incarcerated  
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two methods for hernia repair   approximating adjacent muscles or use of synthetic mesh  
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in this type of hernia the stomach prolapses through the diaphragmatic esophageal hiatus   hiatal hernia  
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following hernia repair, the patient should be encouraged to breathe deeply but discouraged from   coughing  
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most intestinal obstructions occur here   ileum  
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90% of obstruction are due to these two pathologies   adhesions and incarcerated hernias  
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the most common form of non mechanical bowel obstruction   paralytic ileus  
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inflammation of the vermiform appendix located at the tip of the cecum   appendicitis  
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hallmark sign of appendicitis   rebound tenderness  
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treatment of choice for acute appendicitis   appendectomy  
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the presence of pouchlike herniations through the muscular layer of the colon   diverticulosis  
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the inflammation or infection of one or more diverticula   diverticulitis  
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signs and symptoms of diverticulitis   pain in left lower quadrant, fever  
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test of choice for diverticulitis   ct scan with oral contrast  
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diverticulitis or osis caused by muscular atrophy is treated by   low residue diet, stool softeners, and bedrest  
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diverticulitis or osis caused by increased intracolonic pressure and muscle thickening is treated by   high fiber diet of bran, fruits, and vegetables  
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inflammation of the abdominal peritoneum   peritonitis  
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how is peritonitis related to diverticular disease   rupture of diverticula can cause leakage into the peritoneum  
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hallmark symptom of peritonitis   severe abdominal pain  
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this finding on xray is indicative of peritonitis   trapped air under the diaphragm  
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treatment for peritonitis   surgical removal of irritant, antibiotics, NG intubation  
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patient with peritonitis should be placed in this position   semifowler’s  
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laxatives are used to   prevent constipation or to prepare the bowel for radiologic or endoscopic procedures  
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types of laxatives   bulk forming, osmotic cathartics, saline laxatives, stimulants, stool softeners  
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laxatives should generally be administered at this time of day   bedtime  
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during laxative therapy patient should intake more or less fluid than normal?   more  
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varicosities of the lower recrum and anus resulting in congestion of the anal and rectal veins   hemorrhoids  
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an abnormal opening on the cutaneous surface near the anus   fistula  
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a linear ulceration or laceration of the skin of the anus   anal fissure  
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opening of the fistula tract, incising the fistula with a partial anus division   fistulotomy  
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removal of the fistula tract   fistulectomy  
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small reddish appearing lumps at the edge of the anus   hemorrhoids  
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procedural treatment of hemorrhoids   ligation, sclerotherapy, cryotherapy, infrared photocoagulation  
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conservative treatment for hemorrhoids   stool softeners, topical creams, analgesic ointments, sitz baths  
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surgical treatment for hemorrhoids   laser excision, hemorrhoidectomy  
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usually occur as a result of trauma caused by hard stool the overstretches the anal lining and is aggravated by defecation   fissures  
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these can form a local crypt abcess and are common in crohn’s disease   fistulas  
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act on the chemoreceptor trigger zone to inhibit nausea and vomiting   phenothiazines  
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act as antiemetics by diminishing motion sickness   dimenhydrate, scopolamine, meclizine  
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decreases nausea and vomiting by its effects on gastric emptying   metoclopramide  
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block the effects of serotonin at the 5HT3 receptor sites to reduce nausea and vomiting   dlasetron, granisetron, ondansetron  
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