Antipsychotics
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| Which neurotransmitters are imbalanced in Schizophrenia? | show 🗑
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| show | block D2 receptors
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| State the mechanism of action of the 2nd generation antipsychotics? | show 🗑
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| show | 2nd generation cause less EPSEs, less prolactin ADRs, less anticholinergic side effects
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| show | risperidone (Risperdal), quetiapine (Seroquel), olanzepine (Zyprexa), and others
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| show | Although not a drug of choice, haloperidol (Haldol) is still commonly used
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| show | bipolar disorder, treatment-resistant depression, agitation & irritability & aggression in Autism
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| List side effects of the antipsychotics: | show 🗑
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| Define akathisia: | show 🗑
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| show | severe spasms of muscles of tongue, face, neck, or back
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| Define tardive dyskinesia | show 🗑
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| Define Parkinsonism-like movement disorders: | show 🗑
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| Which type of EPSE is associated with long-term use & may be irreversible? | show 🗑
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| Which type of EPSE occurs within the first few days of therapy & is considered a medical emergency? | show 🗑
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| show | blocking D2 receptors
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| show | treat with anticholinergic drugs (diphenhydramine if IV is needed or benztropine if oral is needed)
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| show | anxiety or exacerbation of psychoses
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| show | Elderly patients with dementia-related psychosis treated with antipsychotics are at an increased risk of death
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| Acute dystonia is best treated with: | show 🗑
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| Which 2nd generation antipsychotic has the highest incidence of EPSEs? | show 🗑
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| Which antipsychotic can cause agranulocytosis? | show 🗑
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| show | aripiprazole
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| The most commonly used scale to monitor for tardive dyskinesia is: | show 🗑
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| Which cardiac dysrhythmia can the antipsychotics cause? | show 🗑
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| Endocrine-related ADRs of the antipsychotics include: | show 🗑
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| show | baseline; at 4 months; and annually thereafter
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